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01-06-2011 | Invited Feature Section

Hepatocarcinogenesis: imaging-pathologic correlation

Authors: Young Nyun Park, Myeong-Jin Kim

Published in: Abdominal Radiology | Issue 3/2011

Abstract

Rapid advances in liver surgery, including liver transplantation, radiology, and pathology, have created a need for clinically relevant nomenclature for premalignant and early lesions of hepatocellular carcinoma (HCC). Precancerous lesions include dysplastic foci and dysplastic nodules (DNs) characterized by cytologic or structural atypia. Although imaging diagnosis is playing a crucial role in the evaluation of hepatocarcinogenesis and early diagnosis of HCC, it is still challenging to accurately characterize borderline nodules such as small arterially enhancing lesions or hypovascular nodules. This article discusses pathological and radiological features of these small nodular lesions and offers insights into the multistep process of hepatocarcinogenesis by describing the progression of pathologic change linking DNs to HCC.

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Title: Hepatocarcinogenesis: imaging-pathologic correlation
Authors: Young Nyun Park
Myeong-Jin Kim
Publication date: 01-06-2011
Publisher: Springer-Verlag
Published in: Abdominal Radiology / Issue 3/2011
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI: https://doi.org/10.1007/s00261-011-9688-y

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