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Published in: Abdominal Radiology 6/2008

01-11-2008

The various manifestations of ruptured hepatocellular carcinoma: CT imaging findings

Authors: Hyun Cheol Kim, Dal Mo Yang, Wook Jin, Seong Jin Park

Published in: Abdominal Radiology | Issue 6/2008

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Abstract

Hepatocellular carcinoma (HCC) has a tendency to rupture spontaneously which leads to a life-threatening condition. Disruption of the tumor surface or a tear in a parasitic feeding artery can cause HCC rupture leading to hemoperitoneum. When evaluating patients with a ruptured HCC, CT can detect tumors, determine tumor extent, define the presence of tumor bleeding, and show serial hematoma density changes. Thus, familiarity with the various CT findings of ruptured HCCs is essential to ensure proper diagnosis and treatment. In this pictorial essay, the authors illustrate the usual and unusual manifestations of ruptured HCCs, as visualized by CT, and include some angiographic correlations. CT findings predictive of HCC rupture are also discussed.
Literature
1.
go back to reference Lai EC, Lau WY (2006) Spontaneous rupture of hepatocellular carcinoma: a systematic review Arch Surg 141:191–198PubMedCrossRef Lai EC, Lau WY (2006) Spontaneous rupture of hepatocellular carcinoma: a systematic review Arch Surg 141:191–198PubMedCrossRef
2.
go back to reference Casillas VJ, Amendola MA, Gascue A, et al. (2000) Imaging of nontraumatic hemorrhagic hepatic lesions Radiographics 20:367–378PubMed Casillas VJ, Amendola MA, Gascue A, et al. (2000) Imaging of nontraumatic hemorrhagic hepatic lesions Radiographics 20:367–378PubMed
3.
go back to reference Yeh CN, Lee WC, Jeng LB, et al. (2002) Spontaneous tumour rupture and prognosis in patients with hepatocellular carcinoma Br J Surg 89:1125–1129PubMedCrossRef Yeh CN, Lee WC, Jeng LB, et al. (2002) Spontaneous tumour rupture and prognosis in patients with hepatocellular carcinoma Br J Surg 89:1125–1129PubMedCrossRef
4.
go back to reference Kim PN, Kim IY, Bae WK, et al. (1991) Computed tomographic findings of ruptured hepatic malignancy Gastrointest Radiol 16:334–336PubMedCrossRef Kim PN, Kim IY, Bae WK, et al. (1991) Computed tomographic findings of ruptured hepatic malignancy Gastrointest Radiol 16:334–336PubMedCrossRef
5.
go back to reference Ngan H, Tso WK, Lai CL, et al. (1998) The role of hepatic arterial embolization in the treatment of spontaneous rupture of hepatocellular carcinoma. Clin Radiol 53:338–341PubMedCrossRef Ngan H, Tso WK, Lai CL, et al. (1998) The role of hepatic arterial embolization in the treatment of spontaneous rupture of hepatocellular carcinoma. Clin Radiol 53:338–341PubMedCrossRef
6.
go back to reference Kanematsu M, Imaeda T, Yamawaki Y, et al. (1992) Rupture of hepatocellular carcinoma: predictive value of CT findings AJR Am J Roentgenol 158:1247–1250PubMed Kanematsu M, Imaeda T, Yamawaki Y, et al. (1992) Rupture of hepatocellular carcinoma: predictive value of CT findings AJR Am J Roentgenol 158:1247–1250PubMed
7.
go back to reference Chearanai O, Plengvanit U, Asavanich C, et al. (1983) Spontaneous rupture of primary hepatoma: report of 63 cases with particular reference to the pathogenesis and rationale treatment by hepatic artery ligation Cancer 51:1532–1536PubMedCrossRef Chearanai O, Plengvanit U, Asavanich C, et al. (1983) Spontaneous rupture of primary hepatoma: report of 63 cases with particular reference to the pathogenesis and rationale treatment by hepatic artery ligation Cancer 51:1532–1536PubMedCrossRef
8.
go back to reference Ong GB, Chu EP, Yu FY, et al. (1965) Spontaneous rupture of hepatocellular carcinoma Br J Surg 52:123–129PubMedCrossRef Ong GB, Chu EP, Yu FY, et al. (1965) Spontaneous rupture of hepatocellular carcinoma Br J Surg 52:123–129PubMedCrossRef
9.
go back to reference Nagasue N, Inokuchi K, Kobayashi M, et al. (1977) Hepatoportal arteriovenous fistula in primary carcinoma of the liver Surg Gynecol Obstet 145:504–508PubMed Nagasue N, Inokuchi K, Kobayashi M, et al. (1977) Hepatoportal arteriovenous fistula in primary carcinoma of the liver Surg Gynecol Obstet 145:504–508PubMed
10.
go back to reference Zhu LX, Geng XP, Fan ST (2001) Spontaneous rupture of hepatocellular carcinoma and vascular injury Arch Surg 136:682–687PubMedCrossRef Zhu LX, Geng XP, Fan ST (2001) Spontaneous rupture of hepatocellular carcinoma and vascular injury Arch Surg 136:682–687PubMedCrossRef
11.
go back to reference Lubner M, Menias C, Rucker C, et al. (2007) Blood in the belly: CT findings of hemoperitoneum Radiographics 27:109–125PubMedCrossRef Lubner M, Menias C, Rucker C, et al. (2007) Blood in the belly: CT findings of hemoperitoneum Radiographics 27:109–125PubMedCrossRef
12.
go back to reference Orwig D, Federle MP (1989) Localized clotted blood as evidence of visceral trauma on CT: the sentinel clot sign AJR Am J Roentgenol 153:747–749PubMed Orwig D, Federle MP (1989) Localized clotted blood as evidence of visceral trauma on CT: the sentinel clot sign AJR Am J Roentgenol 153:747–749PubMed
13.
go back to reference Shanmuganathan K, Mirvis SE, Reaney SM (1995) Pictorial review: CT appearances of contrast medium extravasations associated with injury sustained from blunt abdominal trauma Clin Radiol 50:182–187PubMedCrossRef Shanmuganathan K, Mirvis SE, Reaney SM (1995) Pictorial review: CT appearances of contrast medium extravasations associated with injury sustained from blunt abdominal trauma Clin Radiol 50:182–187PubMedCrossRef
14.
go back to reference Chen CY, Lin XZ, Shin JS, et al. (1995) Spontaneous rupture of hepatocellular carcinoma. A review of 141 Taiwanese cases and comparison with nonrupture cases J Clin Gastroenterol 21:238–242PubMedCrossRef Chen CY, Lin XZ, Shin JS, et al. (1995) Spontaneous rupture of hepatocellular carcinoma. A review of 141 Taiwanese cases and comparison with nonrupture cases J Clin Gastroenterol 21:238–242PubMedCrossRef
15.
go back to reference Choi BG, Park SH, Byun JY, et al. (2001) The findings of ruptured hepatocellular carcinoma on helical CT Br J Radiol 74:142–146PubMed Choi BG, Park SH, Byun JY, et al. (2001) The findings of ruptured hepatocellular carcinoma on helical CT Br J Radiol 74:142–146PubMed
16.
go back to reference Kim PT, Su JC, Buczkowski AK, et al. (2006) Computed tomography and angiographic interventional features of ruptured hepatocellular carcinoma: pictorial essay Can Assoc Radiol J 57:159–168PubMed Kim PT, Su JC, Buczkowski AK, et al. (2006) Computed tomography and angiographic interventional features of ruptured hepatocellular carcinoma: pictorial essay Can Assoc Radiol J 57:159–168PubMed
17.
go back to reference Kim TK, Han JK, Chung JW, et al. (1996) Intraperitoneal drop metastases from hepatocellular carcinoma: CT and angiographic findings J Comput Assist Tomogr 20:638–642PubMedCrossRef Kim TK, Han JK, Chung JW, et al. (1996) Intraperitoneal drop metastases from hepatocellular carcinoma: CT and angiographic findings J Comput Assist Tomogr 20:638–642PubMedCrossRef
18.
go back to reference Kim PN, Kim IY, Lee KS (1994) Intraperitoneal seeding from hepatoma Abdom Imaging 19:309–312PubMed Kim PN, Kim IY, Lee KS (1994) Intraperitoneal seeding from hepatoma Abdom Imaging 19:309–312PubMed
Metadata
Title
The various manifestations of ruptured hepatocellular carcinoma: CT imaging findings
Authors
Hyun Cheol Kim
Dal Mo Yang
Wook Jin
Seong Jin Park
Publication date
01-11-2008
Publisher
Springer-Verlag
Published in
Abdominal Radiology / Issue 6/2008
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-007-9353-7

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