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European Journal of Nuclear Medicine and Molecular Imaging

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Open Access 01-04-2022 | Breast Cancer | Image of the Month

First-time imaging of [⁸⁹Zr]trastuzumab in breast cancer using a long axial field-of-view PET/CT scanner

Authors: Adrienne H. Brouwers, Joyce van Sluis, Johannes H. van Snick, Carolina P. Schröder, Inge O. Baas, Ronald Boellaard, Andor W. J. M. Glaudemans, Ronald J. H. Borra, Adriaan A. Lammertsma, Rudi A. J. O. Dierckx, Charalampos Tsoumpas

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 10/2022

Excerpt

Long axial field-of-view (LAFOV) PET/CT scanners have been introduced recently [1, 2], which offer numerous advantages [3]. One important advantage of using LAFOV PET/CT for imaging ⁸⁹Zr-labelled monoclonal antibodies (mAbs), i.e., immunoPET, is the substantial increase in sensitivity compared with standard axial field-of-view (SAFOV) PET/CT systems, which may lead to a remarkable image quality improvement. This first study showcases such improvement for immunoPET with Biograph Vision Quadra™ (VQ) LAFOV PET/CT (Siemens Healthineers, Knoxville, TN, USA). …

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Slart RHJA, Tsoumpas C, Glaudemans AWJM, Noordzij W, Willemsen ATM, Borra RJH, et al. Long axial field of view PET scanners: a road map to implementation and new possibilities. Eur J Nucl Med Mol Imaging. 2021;48:4236–45.CrossRef

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Title: First-time imaging of [89Zr]trastuzumab in breast cancer using a long axial field-of-view PET/CT scanner
Authors: Adrienne H. Brouwers
Joyce van Sluis
Johannes H. van Snick
Carolina P. Schröder
Inge O. Baas
Ronald Boellaard
Andor W. J. M. Glaudemans
Ronald J. H. Borra
Adriaan A. Lammertsma
Rudi A. J. O. Dierckx
Charalampos Tsoumpas
Publication date: 01-04-2022
Publisher: Springer Berlin Heidelberg
Keywords: Breast Cancer
Breast Cancer
Trastuzumab
Published in: European Journal of Nuclear Medicine and Molecular Imaging / Issue 10/2022
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-022-05777-x

ACC 2024 Congress

Springer Medicine

First-time imaging of [⁸⁹Zr]trastuzumab in breast cancer using a long axial field-of-view PET/CT scanner

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ACC 2024 Congress

Springer Medicine

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