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European Journal of Nuclear Medicine and Molecular Imaging
Published in: European Journal of Nuclear Medicine and Molecular Imaging 2/2018

01-02-2018 | Editorial Commentary

Could 68Ga-somatostatin analogues be an important alternative to 18F-DOPA PET/CT in pediatrics?

Authors: Arnoldo Piccardo, Giorgio Treglia

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 2/2018

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Excerpt

A growing body of evidence supports the role of fluorine-18 dihydroxyphenylalanine (18F–DOPA) PET/CT in different types of pediatric diseases [1‐4]. Although, this radiotracer remains not largely available, its routine use is increasing in clinical practice, and it should be considered as an important diagnostic option in those Nuclear Medicine Departments highly specialized in pediatrics. The principal limitation of 18F–DOPA is its high cost due to its not efficient production. Indeed, synthesis of 18F–DOPA has generally been realized using an electrophilic approach. However, this electrophilic strategy produces only low amounts (0.6–2.6 GBq) of 18F–DOPA even when using expensive production methods [5, 6]. …
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Metadata
Title
Could 68Ga-somatostatin analogues be an important alternative to 18F-DOPA PET/CT in pediatrics?
Authors
Arnoldo Piccardo
Giorgio Treglia
Publication date
01-02-2018
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Nuclear Medicine and Molecular Imaging / Issue 2/2018
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI
https://doi.org/10.1007/s00259-017-3894-y

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