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European Journal of Nuclear Medicine and Molecular Imaging

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01-05-2017 | Editorial Commentary

Radionuclide imaging of subendocardial ischaemia: an insight into coronary pathophysiology or a technical artefact?

Authors: Gianmario Sambuceti, Silvia Morbelli, Alessandro Bellini, Cecilia Marini

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 5/2017

Excerpt

In the present issue of the European Journal of Nuclear Medicine and Molecular Imaging, Sciagrà and coworkers report an investigation of the mechanisms underlying a decrease in left ventricular (LV) ejection fraction during dipyridamole-induced coronary vasodilation in a group of patients with hypertrophic cardiomyopathy (HCM) [1]. As a major finding, transient LV dysfunction did not identify patients with more severe impairment in coronary flow reserve and maximal blood flow. Rather, it was associated with stress-induced development of a transmural gradient in myocardial perfusion characterized by a relative reduction in maximal flow capacity in the subendocardial layers. …

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Title: Radionuclide imaging of subendocardial ischaemia: an insight into coronary pathophysiology or a technical artefact?
Authors: Gianmario Sambuceti
Silvia Morbelli
Alessandro Bellini
Cecilia Marini
Publication date: 01-05-2017
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Nuclear Medicine and Molecular Imaging / Issue 5/2017
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-017-3642-3

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