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European Journal of Nuclear Medicine and Molecular Imaging
Published in: European Journal of Nuclear Medicine and Molecular Imaging 7/2016

Open Access 01-07-2016 | Original Article

Analysis of pairwise correlations in multi-parametric PET/MR data for biological tumor characterization and treatment individualization strategies

Authors: Sara Leibfarth, Urban Simoncic, David Mönnich, Stefan Welz, Holger Schmidt, Nina Schwenzer, Daniel Zips, Daniela Thorwarth

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 7/2016

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Excerpt

Biological tumor characterization based on functional and molecular imaging might be highly valuable for radiotherapy (RT). On the one hand, it could allow for an improved target volume definition and an individualized dose prescription within the tumor according to local biological characteristics. Such dose painting strategies can be readily applied with the technical availability of intensity modulated RT (IMRT). Moreover, functional imaging might be of high value for early response assessment and potential treatment adaptation in the course of fractionated RT [1, 2]. Other fields of application are the assessment of chemotherapy and the application of targeted agents, such as hypoxia-sensitizing or antiangiogenic drugs [3, 4]. …
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Metadata
Title
Analysis of pairwise correlations in multi-parametric PET/MR data for biological tumor characterization and treatment individualization strategies
Authors
Sara Leibfarth
Urban Simoncic
David Mönnich
Stefan Welz
Holger Schmidt
Nina Schwenzer
Daniel Zips
Daniela Thorwarth
Publication date
01-07-2016
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Nuclear Medicine and Molecular Imaging / Issue 7/2016
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI
https://doi.org/10.1007/s00259-016-3307-7

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