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European Journal of Nuclear Medicine and Molecular Imaging

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01-10-2011 | Editorial Commentary

Attenuation correction for myocardial perfusion SPECT imaging: still a controversial issue

Author: Alberto Cuocolo

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 10/2011

Excerpt

The use of attenuation correction for cardiac single photon emission computed tomography (SPECT) myocardial perfusion imaging has been discussed from the beginning. The value of attenuation correction is easy to accept, and it is generally recognized that it is important to discern if a tracer deficit is due to diminished myocardial perfusion or if it is an attenuation or motion artefact. An additional important problem is to establish whether the defect is really reversible or represents a result of scatter and interference from extracardiac tracer activity. It seems conceivable that attenuation correction should at least improve the problems related with an attenuation artefact. There are also additional potential advantages of attenuation correction, which have been outlined in many studies. However, the question of whether attenuation correction is needed is still unsolved and it has been debated for a long time. …

Garcia EV. SPECT attenuation correction: an essential tool to realize nuclear cardiology’s manifest destiny. J Nucl Cardiol 2007;14:16–24.PubMedCrossRef

Germano G, Slomka PJ, Berman DS. Attenuation correction in cardiac SPECT: the boy who cried wolf? J Nucl Cardiol 2007;14:25–35.PubMedCrossRef

Grossman GB, Garcia EV, Bateman TM, Heller GV, Johnson LL, Folks RD, et al. Quantitative Tc-99m sestamibi attenuation-corrected SPECT: development and multicenter trial validation of myocardial perfusion stress gender-independent normal database in an obese population. J Nucl Cardiol 2004;11:263–72.PubMedCrossRef

Thompson RC, Heller GV, Johnson LJ, Case JA, Cullom SJ, Garcia EV, et al. Value of attenuation correction on ECG-gated myocardial perfusion imaging related to body mass index. J Nucl Cardiol 2005;12:195–202.PubMedCrossRef

Ficaro EP, Fessler JA, Shreve PD, Kritzman JN, Rose PA, Corbett JR. Simultaneous transmission/emission myocardial perfusion tomography. Diagnostic accuracy of attenuation-corrected 99mTc-sestamibi single-photon emission computed tomography. Circulation 1996;93:463–73.PubMed

Gallowitsch HJ, Sykora J, Mikosch P, Kresnik E, Unterweger O, Molnar M, et al. Attenuation-corrected thallium-201 single-photon emission tomography using a gadolinium-153 moving line source: clinical value and the impact of attenuation correction on the extent and severity of perfusion abnormalities. Eur J Nucl Med 1998;25:220–8.PubMedCrossRef

Hendel RC, Berman DS, Cullom SJ, Follansbee W, Heller GV, Kiat H, et al. Multicenter clinical trial to evaluate the efficacy of correction for photon attenuation and scatter in SPECT myocardial perfusion imaging. Circulation 1999;99:2742–9.PubMed

Links JM, Becker LC, Rigo P, Taillefer R, Hanelin L, Anstett F, et al. Combined corrections for attenuation, depth-dependent blur, and motion in cardiac SPECT: a multicenter trial. J Nucl Cardiol 2000;7:414–25.PubMedCrossRef

Shotwell M, Singh BM, Fortman C, Bauman BD, Lukes J, Gerson MC. Improved coronary disease detection with quantitative attenuation-corrected Tl-201 images. J Nucl Cardiol 2002;9:52–62.PubMedCrossRef

10.

Slart RH, Que TH, van Veldhuisen DJ, Poot L, Blanksma PK, Piers DA, et al. Effect of attenuation correction on the interpretation of 99mTc-sestamibi myocardial perfusion scintigraphy: the impact of 1 year’s experience. Eur J Nucl Med Mol Imaging 2003;30:1505–9.PubMedCrossRef

11.

Banzo I, Pena FJ, Allende RH, Quirce R, Carrill JM. Prospective clinical comparison of non-corrected and attenuation- and scatter-corrected myocardial perfusion SPECT in patients with suspicion of coronary artery disease. Nucl Med Commun 2003;24:995–1002.PubMedCrossRef

12.

Masood Y, Liu YH, DePuey G, Taillefer R, Araujo LI, Allen S, et al. Clinical validation of SPECT attenuation correction using x-ray computed tomography-derived attenuation maps: multicenter clinical trial with angiographic correlation. J Nucl Cardiol 2005;12:676–86.PubMedCrossRef

13.

Utsunomiya D, Tomiguchi S, Shiraishi S, Yamada K, Honda T, Kawanaka K, et al. Initial experience with X-ray CT based attenuation correction in myocardial perfusion SPECT imaging using a combined SPECT/CT system. Ann Nucl Med 2005;19:485–9.PubMedCrossRef

14.

Hendel RC, Corbett JR, Cullom SJ, DePuey EG, Garcia EV, Bateman TM. The value and practice of attenuation correction for myocardial perfusion SPECT imaging: a joint position statement from the American Society of Nuclear Cardiology and the Society of Nuclear Medicine. J Nucl Cardiol 2002;9:135–43.PubMedCrossRef

15.

Patton JA, Townsend DW, Hutton BF. Hybrid imaging technology: from dreams and vision to clinical devices. Semin Nucl Med 2009;39:247–63.PubMedCrossRef

16.

Genovesi D, Giorgetti A, Gimelli A, Kusch A, D’Aragona Tagliavia I, Casagranda M, et al. Impact of attenuation correction and gated acquisition in SPECT myocardial perfusion imaging: results of the multicentre SPAG (SPECT Attenuation Correction vs Gated) study. Eur J Nucl Med Mol Imaging 2011. doi:10.1007/s00259-011-1855-4.

17.

Wolak A, Slomka PJ, Fish MB, Lorenzo S, Berman DS, Germano G. Quantitative diagnostic performance of myocardial perfusion SPECT with attenuation correction in women. J Nucl Med 2008;49:915–22.PubMedCrossRef

18.

Case J, Cullom S, Bateman TM. Myocardial perfusion single-photon emission computed tomography attenuation correction. 3rd ed. New York: Oxford University Press; 2003.

19.

Links JM, Becker LC, Anstett F. Clinical significance of apical thinning after attenuation correction. J Nucl Cardiol 2004;11:26–31.PubMedCrossRef

20.

Van Train KF, Garcia EV, Maddahi J, Areeda J, Cooke CD, Kiat H, et al. Multicenter trial validation for quantitative analysis of same-day rest-stress technetium-99m-sestamibi myocardial tomograms. J Nucl Med 1994;35:609–18.PubMed

21.

Slomka PJ, Fish MB, Lorenzo S, Nishina H, Gerlach J, Berman DS, et al. Simplified normal limits and automated quantitative assessment for attenuation-corrected myocardial perfusion SPECT. J Nucl Cardiol 2006;13:642–51.PubMedCrossRef

22.

Hendel RC. Attenuation correction: eternal dilemma or real improvement? Q J Nucl Med Mol Imaging 2005;49:30–42.PubMed

Title: Attenuation correction for myocardial perfusion SPECT imaging: still a controversial issue
Author: Alberto Cuocolo
Publication date: 01-10-2011
Publisher: Springer-Verlag
Published in: European Journal of Nuclear Medicine and Molecular Imaging / Issue 10/2011
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-011-1898-6

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