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Skeletal Radiology
Published in: Skeletal Radiology 5/2019

01-05-2019 | Doxycycline | Scientific Article

Aneurysmal bone cyst treated with percutaneous doxycycline: is a single treatment sufficient?

Authors: Jason T. K. Woon, Damien Hoon, Andrew Graydon, Mike Flint, Anthony J. Doyle

Published in: Skeletal Radiology | Issue 5/2019

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Abstract

Objective

The purpose of this case series is to report on the effectiveness of a single percutaneous injection of doxycycline as a primary treatment for aneurysmal bone cyst (ABC).

Materials and methods

A retrospective cohort study was conducted on seven patients diagnosed with ABC at various anatomical sites, with the intention to treat by a single percutaneous injection of doxycycline. Mean patient age was 14 years.

Results

Signs of treatment response were seen in six of seven patients after one injection. Three of the seven received a second treatment, despite signs of response. Another had expansion of the lesion after treatment, requiring excision. In total, three patients had a single injection of doxycycline as their sole treatment and another three showed signs of response after a single injection.

Conclusions

A single percutaneous injection of doxycycline should be considered a viable primary treatment option for ABC.
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Metadata
Title
Aneurysmal bone cyst treated with percutaneous doxycycline: is a single treatment sufficient?
Authors
Jason T. K. Woon
Damien Hoon
Andrew Graydon
Mike Flint
Anthony J. Doyle
Publication date
01-05-2019
Publisher
Springer Berlin Heidelberg
Published in
Skeletal Radiology / Issue 5/2019
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-019-03188-y

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