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Published in: Skeletal Radiology 8/2004

01-08-2004 | Case Report

Differentiated adamantinoma of the fibula: a rhabdoid variant

Authors: C. Povýšil, A. Kohout, K. Urban, M. Horák

Published in: Skeletal Radiology | Issue 8/2004

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Abstract

A benign- appearing osteolytic lesion surrounded by a sclerotic rim was found in the upper fibula of a 25-year-old man. Based on histological features the definitive diagnosis of osteofibrous dysplasia–differentiated adamantinoma was made. The correct histological diagnosis of differentiated adamantinoma depends on factors such as the uniform predominance of an osteofibrous dysplasia-like pattern, and scattered epithelial elements positive for cytokeratin and vimentin. In this case the scattered epithelial cells had abundant eosinophilic cytoplasm and resembled rhabdoid elements, but immunohistochemistry proved their epithelial origin.
Literature
1.
go back to reference Kempson RL. Ossifying fibroma of the long bones. Arch Pathol 1966; 64:730–737. Kempson RL. Ossifying fibroma of the long bones. Arch Pathol 1966; 64:730–737.
2.
go back to reference Johnson LC. Congenital pseudoarthrosis, adamantinoma of long bone and intracortical fibrous dysplasia of the tibia. J Bone Joint Surg Am 1972; 54:1355. Johnson LC. Congenital pseudoarthrosis, adamantinoma of long bone and intracortical fibrous dysplasia of the tibia. J Bone Joint Surg Am 1972; 54:1355.
3.
go back to reference Markel SF. Ossifying fibroma of long bone. Its distinction from fibrous dysplasia and its association with adamantinoma of long bone. Am J Clin Pathol 1978; 69:91–97.PubMed Markel SF. Ossifying fibroma of long bone. Its distinction from fibrous dysplasia and its association with adamantinoma of long bone. Am J Clin Pathol 1978; 69:91–97.PubMed
4.
go back to reference Campanacci M, Laus M. Osteofibrous dysplasia of the tibia and fibula. J. Bone Joint Surg Am 1981; 63:367–375. Campanacci M, Laus M. Osteofibrous dysplasia of the tibia and fibula. J. Bone Joint Surg Am 1981; 63:367–375.
5.
go back to reference Czerniak B, Rojas-Corona RR, Dorfman HD. Morphologic diversity of long bone adamantinoma. The concept of differentiated (regressing) adamantinoma and its relationship to osteofibrous dysplasia. Cancer 1989; 64:2319–2334.PubMed Czerniak B, Rojas-Corona RR, Dorfman HD. Morphologic diversity of long bone adamantinoma. The concept of differentiated (regressing) adamantinoma and its relationship to osteofibrous dysplasia. Cancer 1989; 64:2319–2334.PubMed
6.
go back to reference Sweet DE, Vinh TN, Devaney K. Cortical osteofibrous dysplasia of long bone and its relationship to adamantinoma. Am J Surg Pathol 1992; 16:282–290.PubMed Sweet DE, Vinh TN, Devaney K. Cortical osteofibrous dysplasia of long bone and its relationship to adamantinoma. Am J Surg Pathol 1992; 16:282–290.PubMed
7.
go back to reference Benassi MS, Campanacci L, Gamberi G, Ferrari C, Picci P, Sangiorgi L, Campanassi M. Cytokeratin expression and distribution in adamantinoma of the long bones and osteofibrous dysplasia of tibia and fibula. An immunohistochemical study correlated to histogenesis. Histopathology 1994; 25:71–76.PubMed Benassi MS, Campanacci L, Gamberi G, Ferrari C, Picci P, Sangiorgi L, Campanassi M. Cytokeratin expression and distribution in adamantinoma of the long bones and osteofibrous dysplasia of tibia and fibula. An immunohistochemical study correlated to histogenesis. Histopathology 1994; 25:71–76.PubMed
8.
go back to reference Park YK, Unni KK, McLeod RA, Pritchard DJ. Osteofibrous dysplasia: clinicopathologic study of 80 cases. Hum Pathol 1993; 24:1339–1347.PubMed Park YK, Unni KK, McLeod RA, Pritchard DJ. Osteofibrous dysplasia: clinicopathologic study of 80 cases. Hum Pathol 1993; 24:1339–1347.PubMed
9.
go back to reference Adler CP. Case 587. Adamantinoma of tibia mimicking osteofibrous dysplasia. Skeletal Radiol 1990; 19:55–58.PubMed Adler CP. Case 587. Adamantinoma of tibia mimicking osteofibrous dysplasia. Skeletal Radiol 1990; 19:55–58.PubMed
10.
go back to reference Weiss SW, Dorfman HD. Adamantinoma of long bone. An analysis of nine cases with emphasis on metastasising lesions and fibrous dysplasia-like changes. Hum Pathol 1977; 8:141–153.PubMed Weiss SW, Dorfman HD. Adamantinoma of long bone. An analysis of nine cases with emphasis on metastasising lesions and fibrous dysplasia-like changes. Hum Pathol 1977; 8:141–153.PubMed
11.
go back to reference Jundt FG, Remberger K, Roessner A, Schulz A, Bohndorf K. Adamantinoma of long bones. A histopathological and immunohistochemical study of 23 cases. Pathol Res Pract 1995; 191:112–120.PubMed Jundt FG, Remberger K, Roessner A, Schulz A, Bohndorf K. Adamantinoma of long bones. A histopathological and immunohistochemical study of 23 cases. Pathol Res Pract 1995; 191:112–120.PubMed
12.
go back to reference Kumar D, Mulligan ME, Levine AM, Dorfman HD. Classic adamantinoma in 3-year-old. Skeletal Radiol 1998; 27:406–409.CrossRefPubMed Kumar D, Mulligan ME, Levine AM, Dorfman HD. Classic adamantinoma in 3-year-old. Skeletal Radiol 1998; 27:406–409.CrossRefPubMed
13.
go back to reference Resnik CS, Young JWR, Levine AM, Aisner SC. Case report 604. Osteofibrous dysplasia of the tibia. Skeletal Radiol 1990; 19:217–219.PubMed Resnik CS, Young JWR, Levine AM, Aisner SC. Case report 604. Osteofibrous dysplasia of the tibia. Skeletal Radiol 1990; 19:217–219.PubMed
14.
go back to reference Mirra JM. Adamantinoma and osteofibrous dysplasia. In: Bone tumors: clinical, radiologic, and pathologic correlations. Philadelphia: Lea and Febiger, 1989:1204–1231. Mirra JM. Adamantinoma and osteofibrous dysplasia. In: Bone tumors: clinical, radiologic, and pathologic correlations. Philadelphia: Lea and Febiger, 1989:1204–1231.
15.
go back to reference Fischer B. Ueber ein primares Adamantinom der Tibia. Frankfurt Z Pathol 1913; 12:422–441. Fischer B. Ueber ein primares Adamantinom der Tibia. Frankfurt Z Pathol 1913; 12:422–441.
16.
go back to reference Povýšil C, Matìjovský Z. Ultrastructure of adamantinoma of long bones. Virchows Arch A Pathol Anat Histopathol 1981; 393:233–244. Povýšil C, Matìjovský Z. Ultrastructure of adamantinoma of long bones. Virchows Arch A Pathol Anat Histopathol 1981; 393:233–244.
17.
go back to reference Lederer H, Sinclair AJ. Malignant synovioma simulating “adamantinoma of the tibia”. J Pathol 1954; 67:163–168. Lederer H, Sinclair AJ. Malignant synovioma simulating “adamantinoma of the tibia”. J Pathol 1954; 67:163–168.
18.
go back to reference Hazelbag HM, Fleuren GJ, Van den Broek LJCM, Taminiau AHM, Hogendoorn PCW. Adamantinoma of the long bones: keratin subclass immunoreactivity pattern with reference to its histogenesis. Am J Surg Pathol 1993, 17:1225–1233. Hazelbag HM, Fleuren GJ, Van den Broek LJCM, Taminiau AHM, Hogendoorn PCW. Adamantinoma of the long bones: keratin subclass immunoreactivity pattern with reference to its histogenesis. Am J Surg Pathol 1993, 17:1225–1233.
19.
go back to reference Unni KK. Adamantinoma of long bones: the mystery endures. Adv Anat Pathol 1996; 1:16–21. Unni KK. Adamantinoma of long bones: the mystery endures. Adv Anat Pathol 1996; 1:16–21.
20.
go back to reference Hazelbag MH, Van den Broek LJCM, Fleuren GJ, Taminiau AHM, Hogendoorn PCW. Distribution of extracellular matrix components in adamantinoma of long bones suggests fibrous to epithelial transformation. Hum Pathol 1997; 28:183–188.PubMed Hazelbag MH, Van den Broek LJCM, Fleuren GJ, Taminiau AHM, Hogendoorn PCW. Distribution of extracellular matrix components in adamantinoma of long bones suggests fibrous to epithelial transformation. Hum Pathol 1997; 28:183–188.PubMed
21.
go back to reference Bridge JA, Dembinski A, De Boer J, Travis J, Neff JR. Clonal chromosomal abnormalities in osteofibrous dysplasia: implications for histopathogenesis and its relationship with adamantinoma. Cancer 1994; 73:1746–1752. Bridge JA, Dembinski A, De Boer J, Travis J, Neff JR. Clonal chromosomal abnormalities in osteofibrous dysplasia: implications for histopathogenesis and its relationship with adamantinoma. Cancer 1994; 73:1746–1752.
22.
go back to reference Kahn LB. Review article. Adamantinoma, osteofibrous dysplasia and differentiated adamantinoma. Skeletal Radiol 2003; 32:245–258.PubMed Kahn LB. Review article. Adamantinoma, osteofibrous dysplasia and differentiated adamantinoma. Skeletal Radiol 2003; 32:245–258.PubMed
Metadata
Title
Differentiated adamantinoma of the fibula: a rhabdoid variant
Authors
C. Povýšil
A. Kohout
K. Urban
M. Horák
Publication date
01-08-2004
Publisher
Springer-Verlag
Published in
Skeletal Radiology / Issue 8/2004
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-004-0755-0

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