Top

Published in:

01-02-2019 | Pictorial Essay

Added value of arterial spin labeling magnetic resonance imaging in pediatric neuroradiology: pitfalls and applications

Authors: Vera C. Keil, Nolan S. Hartkamp, Daniel J. A. Connolly, Giovanni Morana, Marjolein H. G. Dremmen, Henk J. M. M. Mutsaerts, Maarten H. Lequin

Published in: Pediatric Radiology | Issue 2/2019

Abstract

Arterial spin labeling is a noninvasive, non-gadolinium-dependent magnetic resonance imaging (MRI) technique to assess cerebral blood flow. It provides insight into both tissue metabolic activity and vascular supply. Because of its non-sensitivity toward blood–brain barrier leakage, arterial spin labeling is also more accurate in cerebral blood flow quantification than gadolinium-dependent methods. The aim of this pictorial essay is to promote the application of arterial spin labeling in pediatric neuroradiology. The authors provide information on artifacts and pitfalls as well as numerous fields of application based on pediatric cases.

Goetti R, Warnock G, Kuhn FP et al (2014) Quantitative cerebral perfusion imaging in children and young adults with Moyamoya disease: comparison of arterial spin-labeling-MRI and H(2)[(15)O]-PET. AJNR Am J Neuroradiol 35:1022–1028CrossRefPubMed

Armitage PA, Skipper N, Connolly DJ et al (2017) A qualitative comparison of arterial spin labelling and dynamic susceptibility contrast MRI in 52 children with a range of neurological conditions. Br J Radiol 90:20160495CrossRefPubMed

Wang J, Licht DJ, Jahng GH et al (2003) Pediatric perfusion imaging using pulsed arterial spin labeling. J Magn Reson Imaging 18:404–413CrossRefPubMed

Petersen ET, Zimine I, Ho YC et al (2006) Non-invasive measurement of perfusion: a critical review of arterial spin labelling techniques. Br J Radiol 79:688–701CrossRefPubMed

Miranda MJ, Olofsson K, Sidaros K (2006) Noninvasive measurements of regional cerebral perfusion in preterm and term neonates by magnetic resonance arterial spin labeling. Pediatr Res 60:359–363CrossRefPubMed

Chen J, Licht DJ, Smith SE et al (2009) Arterial spin labeling perfusion MRI in pediatric arterial ischemic stroke: initial experiences. J Magn Reson Imaging 29:282–290CrossRefPubMedPubMedCentral

Mutsaerts HJ, Petr J, Vaclavu L et al (2017) The spatial coefficient of variation in arterial spin labeling cerebral blood flow images. J Cereb Blood Flow Metab 37:3184–3192CrossRefPubMedPubMedCentral

Oishi M, Ishida G, Morii K et al (2012) Ictal focal hyperperfusion demonstrated by arterial spin-labeling perfusion MRI in partial epilepsy status. Neuroradiology 54:653–656CrossRefPubMed

Qiu M, Ramani R, Swetye M et al (2008) Anesthetic effects on regional CBF, BOLD, and the coupling between task-induced changes in CBF and BOLD: an fMRI study in normal human subjects. Magn Reson Med 60:987–996CrossRefPubMedPubMedCentral

10.

Harreld JH, Helton KJ, Kaddoum RN et al (2013) The effects of propofol on cerebral perfusion MRI in children. Neuroradiology 55:1049–1056CrossRefPubMedPubMedCentral

11.

Strother MK, Buckingham C, Faraco CC et al (2016) Crossed cerebellar diaschisis after stroke identified noninvasively with cerebral blood flow-weighted arterial spin labeling MRI. Eur J Radiol 85:136–142CrossRefPubMed

12.

Dangouloff-Ros V, Deroulers C, Foissac F et al (2016) Arterial spin labeling to predict brain tumor grading in children: correlations between histopathologic vascular density and perfusion MR imaging. Radiology 281:553–566CrossRefPubMed

13.

Boulouis G, Dangouloff-Ros V, Boccara O et al (2017) Arterial spin-labeling to discriminate pediatric cervicofacial soft-tissue vascular anomalies. AJNR Am J Neuroradiol 38:633–638CrossRefPubMed

14.

Nabavizadeh SA, Edgar JC, Vossough A (2014) Utility of susceptibility-weighted imaging and arterial spin perfusion imaging in pediatric brain arteriovenous shunting. Neuroradiology 56:877–884CrossRefPubMed

15.

Ikawa M, Yoneda M, Muramatsu T et al (2013) Detection of preclinically latent hyperperfusion due to stroke-like episodes by arterial spin-labeling perfusion MRI in MELAS patients. Mitochondrion 13:676–680CrossRefPubMed

Title: Added value of arterial spin labeling magnetic resonance imaging in pediatric neuroradiology: pitfalls and applications
Authors: Vera C. Keil
Nolan S. Hartkamp
Daniel J. A. Connolly
Giovanni Morana
Marjolein H. G. Dremmen
Henk J. M. M. Mutsaerts
Maarten H. Lequin
Publication date: 01-02-2019
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Radiology / Issue 2/2019
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-018-4269-7

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Added value of arterial spin labeling magnetic resonance imaging in pediatric neuroradiology: pitfalls and applications

Abstract

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 2/2019

Magnetic resonance imaging of sacroiliitis in children: reply to Jalalvandi and Naderi

Fetal brain morphometry on prenatal magnetic resonance imaging in congenital diaphragmatic hernia

MR angiography and 2-D phase-contrast imaging for evaluation of meso-rex bypass function

Diagnostic yield of head CT in pediatric emergency department patients with acute psychosis or hallucinations

Cerebral oxygen metabolism during and after therapeutic hypothermia in neonatal hypoxic–ischemic encephalopathy: a feasibility study using magnetic resonance imaging

Parents’ received and expected information about their child’s radiation exposure during radiographic examinations