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Pediatric Radiology
Published in: Pediatric Radiology 6/2016

01-05-2016 | Pediatric Body MRI

Diffusion-weighted imaging in pediatric body magnetic resonance imaging

Authors: Govind B. Chavhan, Pablo Caro-Dominguez

Published in: Pediatric Radiology | Issue 6/2016

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Abstract

Diffusion-weighted MRI is being increasingly used in pediatric body imaging. Its role is still emerging. It is used for detection of tumors and abscesses, differentiation of benign and malignant tumors, and detection of inflamed bowel segments in inflammatory bowel disease in children. It holds great promise in the assessment of therapy response in body tumors, with apparent diffusion coefficient (ADC) value as a potential biomarker. Significant overlap of ADC values of benign and malignant processes and less reproducibility of ADC measurements are hampering its widespread use in clinical practice. With standardization of the technique, diffusion-weighted imaging (DWI) is likely to be used more frequently in clinical practice. We discuss the principles and technique of DWI, selection of b value, qualitative and quantitative assessment, and current status of DWI in evaluation of disease processes in the pediatric body.
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Metadata
Title
Diffusion-weighted imaging in pediatric body magnetic resonance imaging
Authors
Govind B. Chavhan
Pablo Caro-Dominguez
Publication date
01-05-2016
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Radiology / Issue 6/2016
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-016-3573-3

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