Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Pediatric Radiology
Published in: Pediatric Radiology 7/2007

01-07-2007 | Commentary

PET-CT in pediatric Langerhans cell histiocytosis

Authors: Sue C. Kaste, Carlos Rodriguez-Galindo, Mary E. McCarville, Barry L. Shulkin

Published in: Pediatric Radiology | Issue 7/2007

Login to get access

Abstract

Our objective was to assess the utility of PET-CT in five pediatric patients with Langerhans cell histiocytosis (LCH) who underwent PET-CT imaging for clinical staging and determination of lesion activity at various stages of treatment and follow-up. PET-CT combines the anatomic detail of CT and the physiologic activity of 18F-FDG imaging. We conclude that PET-CT information is clinically useful to evaluate disease activity and response to therapy and provides information that cannot be obtained from technetium 99m methylene diphosphonate bone scans or radiographs.
Literature
1.
Azouz EM, Saigal G, Rodriguez MM et al (2005) Langerhans cell histiocytosis: pathology, imaging and treatment of skeletal involvement. Pediatr Radiol 35:103–115PubMedCrossRef
2.
Jubran RF, Marachelian A, Dorey F et al (2005) Predictors of outcome in children with Langerhans cell histiocytosis. Pediatr Blood Cancer 45:37–42PubMedCrossRef
3.
Binkovitz LA, Olshefski RS, Adler BH (2003) Coincidence FDG-PET in the evaluation of Langerhans’ cell histiocytosis: preliminary findings. Pediatr Radiol 33:598–602PubMedCrossRef
4.
Kellenberger CJ, Epelman M, Miller SF et al (2004) Fast STIR whole-body MR imaging in children. Radiographics 24:1317–1330PubMedCrossRef
5.
Minkov M, Grois N, Heitger A et al (2002) Response to initial treatment of multisystem Langerhans cell histiocytosis: an important prognostic indicator. Med Pediatr Oncol 39:581–585PubMedCrossRef
Metadata
Title
PET-CT in pediatric Langerhans cell histiocytosis
Authors
Sue C. Kaste
Carlos Rodriguez-Galindo
Mary E. McCarville
Barry L. Shulkin
Publication date
01-07-2007
Publisher
Springer-Verlag
Published in
Pediatric Radiology / Issue 7/2007
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-007-0467-4

Other articles of this Issue 7/2007

Pediatric Radiology 7/2007 Go to the issue

Original Article

Coronary magnetic resonance angiography and vessel wall imaging in children with Kawasaki disease

Case Report

MR imaging of isolated left ventricular apical hypoplasia

Clinical Image

Choroid plexus papilloma of the third ventricle

Pictorial Essay

Imaging features of gastrointestinal tract duplications in infants and children: from oesophagus to rectum

Letter to the Editor

Another case of transplacental passage of the non-ionic contrast agent ioversol

Original Article

Childhood acute pyelonephritis: comparison of power Doppler sonography and Tc-DMSA scintigraphy