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01-06-2021 | Echocardiography | Original Article

Evaluating Left Ventricular Systolic Synchronicity with Real-Time 3D Echocardiography in Newborns

Authors: Min Xu, Weidong Ren, Feng Xiong, Shuzhen Wang, Lijuan Zhang, Chunxia Liu, Xiaofeng Huang, Yali Lei

Published in: Pediatric Cardiology | Issue 5/2021

Abstract

Knowing the normal values of left ventricular (LV) systolic synchronicity in the early neonatal period is very important for understanding myocardial function. This retrospective study analyzed data of 105 newborns who were examined using real-time 3-dimensional echocardiography (RT3DE). The time to the point of minimal regional systolic volume (Tmsv) was measured from volume–time curves in each segment. Standard deviation (SD) and maximal difference (Dif) of Tmsv were calculated from 16 (6 basal/6 mid/4 apical), 12 (6 basal/6 mid), and 6 (basal) LV segments with the corresponding parameters adjusted for the R–R interval. Influences of age, sex, gestational age, birth weight, and heart rate on parameters were explored. Data showed no significant difference among Tmsv-16-SD, Tmsv-12-SD, and Tmsv-6-SD. A strong correlation was found between Tmsv-6-SD and Tmsv-6-Dif (r = 0.83, P < 0.001), Tmsv-12-SD and Tmsv-6-SD (r = 0.77, P < 0.001), and Tmsv-12-Dif and Tmsv-6-Dif (r = 0.76, P < 0.001) and a moderate correlation was found between Tmsv-16-SD and Tmsv-16-Dif (r = 0.66, P < 0.001), Tmsv-6-SD and Tmsv-12-Dif (r = 0.62, P < 0.001), and Tmsv-12-SD and Tmsv-6-Dif (r = 0.61, P < 0.001). Heart rate correlated negatively with Tmsv (r = − 0.03 to − 0.11, P < 0.004–0.000), but had no effect on parameters adjusted for %R–R. Age, sex, gestational age, and birth weight did not affect any of these parameters. Tmsv-Dif and Tmsv-SD measured from 16 segments using RT3DE are useful as possible parameters for evaluating LV systolic synchronicity in normal newborns.

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Title: Evaluating Left Ventricular Systolic Synchronicity with Real-Time 3D Echocardiography in Newborns
Authors: Min Xu
Weidong Ren
Feng Xiong
Shuzhen Wang
Lijuan Zhang
Chunxia Liu
Xiaofeng Huang
Yali Lei
Publication date: 01-06-2021
Publisher: Springer US
Keywords: Echocardiography
Echocardiography
Published in: Pediatric Cardiology / Issue 5/2021
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI: https://doi.org/10.1007/s00246-021-02601-5

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