Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Pediatric Cardiology
Published in: Pediatric Cardiology 5/2017

01-06-2017 | Review Article

Complete Repair of Tetralogy of Fallot in the Neonatal Versus Non-neonatal Period: A Meta-analysis

Authors: Rohit S. Loomba, Matthew W. Buelow, Ronald K. Woods

Published in: Pediatric Cardiology | Issue 5/2017

Login to get access

Abstract

It is unclear if neonatal tetralogy of Fallot repair offers better outcomes compared to repair later in infancy. We therefore conducted a meta-analysis comparing outcomes of neonatal and non-neonatal repair. Manuscripts were identified and reviewed for quality and bias with favorably scored manuscripts being included in the final meta-analysis. Several perioperative and postoperative variables were compared. A total of 8 studies with 3858 patients were included in the analysis. Of these patients, 19% underwent neonatal repair. Neonatal repair was associated with increased mortality, longer intensive care unit stays, and longer total hospital length of stay.
Literature
1.
Woldu KL, Arya B, Bacha EA, Williams IA (2014) Impact of neonatal versus nonneonatal total repair of tetralogy of fallot on growth in the first year of life. Ann Thorac Surg 98:1399–1404CrossRefPubMed
2.
Kanter KR, Kogon BE, Kirshbom PM, Carlock PR (2010) Symptomatic neonatal tetralogy of Fallot: repair or shunt? Ann Thorac Surg 89:858–863CrossRefPubMed
3.
Kolcz J, Pizarro C (2005) Neonatal repair of tetralogy of Fallot results in improved pulmonary artery development without increased need for reintervention. Eur J Cardiothorac Surg 28:394–399CrossRefPubMed
4.
Reddy VM, Liddicoat JR, McElhinney DB, Brook MM, Stanger P, Hanley FL (1995) Routine primary repair of tetralogy of Fallot in neonates and infants less than three months of age. Ann Thorac Surg 60:S592–S596CrossRefPubMed
5.
Steiner MB, Tang X, Gossett JM, Beam BW, Malik S, Prodhan P, Angtuaco MJ (2015) Alternative repair strategies for ductal-dependent tetralogy of fallot and short-term postoperative outcomes, a multicenter analysis. Pediatr Cardiol 36:177–189CrossRefPubMed
6.
Tamesberger MI, Lechner E, Mair R, Hofer A, Sames-Dolzer E, Tulzer G (2008) Early primary repair of tetralogy of fallot in neonates and infants less than four months of age. Ann Thorac Surg 86:1928–1935CrossRefPubMed
7.
Pigula FA, Khalil PN, Mayer JE, del Nido PJ, Jonas RA (1999) Repair of tetralogy of Fallot in neonates and young infants. Circulation 100: II157–161
8.
Al Habib HF, Jacobs JP, Mavroudis C, Tchervenkov CI, O’Brien SM, Mohammadi S, Jacobs ML (2010) Contemporary patterns of management of tetralogy of Fallot: data from the Society of Thoracic Surgeons Database. Ann Thorac Surg 90:813–819 (discussion 819–820)CrossRefPubMed
9.
Ylitalo P, Nieminen H, Pitkanen OM, Jokinen E, Sairanen H (2015) Need of transannular patch in tetralogy of Fallot surgery carries a higher risk of reoperation but has no impact on late survival: results of Fallot repair in Finland. Eur J Cardiothorac Surg 48:91–97CrossRefPubMed
10.
Kim H, Sung SC, Kim SH, Chang YH, Lee HD, Park JA, Lee YS (2013) Early and late outcomes of total repair of tetralogy of Fallot: risk factors for late right ventricular dilatation. Interact Cardiovasc Thorac Surg 17:956–962CrossRefPubMedPubMedCentral
11.
Kirklin JW, Blackstone EH, Kirklin JK, Pacifico AD, Aramendi J, Bargeron LM Jr (1983) Surgical results and protocols in the spectrum of tetralogy of Fallot. Ann Surg 198:251–265CrossRefPubMedPubMedCentral
12.
Vobecky SJ, Williams WG, Trusler GA, Coles JG, Rebeyka IM, Smallhorn J, Burrows P, Gow R, Freedom RM (1993) Survival analysis of infants under age 18 months presenting with tetralogy of Fallot. Ann Thorac Surg 56:944–949 (discussion 949–950)CrossRefPubMed
13.
Selmonosky CA, Farhangian D, Folger GM, Ellison RG (1972) Palliative shunting operations in tetralogy of Fallot. Effects upon the results of total correction. Ann Thorac Surg 14:16–23CrossRefPubMed
14.
Bove EL, Kohman L, Sereika S, Byrum CJ, Kavey RE, Blackman MS, Sondheimer HM, Rosenthal A (1987) The modified Blalock-Taussig shunt: analysis of adequacy and duration of palliation. Circulation 76: III19–23PubMed
15.
Chopra PS, Levy JM, Dacumos GC Jr, Berkoff HA, Loring LL, Kahn DR (1976) The Blalock-Taussig operation: the procedure of choice in the hypoxic infant with tetralogy of Fallot. Ann Thorac Surg 22:235–238CrossRefPubMed
16.
Gladman G, McCrindle BW, Williams WG, Freedom RM, Benson LN (1997) The modified Blalock-Taussig shunt: clinical impact and morbidity in Fallot’s tetralogy in the current era. J Thorac Cardiovasc Surg 114:25–30CrossRefPubMed
17.
Blalock A, Taussig HB (1984) Landmark article May 19, 1945: the surgical treatment of malformations of the heart in which there is pulmonary stenosis or pulmonary atresia. By Alfred Blalock and Helen B. Taussig. JAMA 251:2123–2138CrossRefPubMed
18.
19.
Lillehei CW, Cohen M, Warden HE, Read RC, Aust JB, Dewall RA, Varco RL (1955) Direct vision intracardiac surgical correction of the tetralogy of Fallot, pentalogy of Fallot, and pulmonary atresia defects; report of first ten cases. Ann Surg 142:418–442CrossRefPubMedPubMedCentral
20.
Kirklin J, DuShane J, Patrick R, Donald D, Hetzel P, Harshbarger H, Wood E (1955) Intracardiac surgery with the help of a mechanical pump-oxygenator system (Gibbon type): report of eight cases. Mayo Clin Proc 30:201
Metadata
Title
Complete Repair of Tetralogy of Fallot in the Neonatal Versus Non-neonatal Period: A Meta-analysis
Authors
Rohit S. Loomba
Matthew W. Buelow
Ronald K. Woods
Publication date
01-06-2017
Publisher
Springer US
Published in
Pediatric Cardiology / Issue 5/2017
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-017-1579-8

Other articles of this Issue 5/2017

Pediatric Cardiology 5/2017 Go to the issue

Original Article

The Evolution of a Pediatric Ventricular Assist Device Program: The Boston Children’s Hospital Experience

Original Article

Hyperoxia Reduces Oxygen Consumption in Children with Pulmonary Hypertension

Original Article

MicroRNAs Association in the Cardiac Hypertrophy Secondary to Complex Congenital Heart Disease in Children

Erratum

Erratum to: Decreased Diastolic Ventricular Kinetic Energy in Young Patients with Fontan Circulation Demonstrated by Four-Dimensional Cardiac Magnetic Resonance Imaging

Original Article

Delayed Myocardial Enhancement in Pediatric Hypertrophic Cardiomyopathy: Correlation with LV Function, Echocardiography, and Demographic Parameters

Upcoming Events

Upcoming Events in Pediatric Cardiology

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits