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Pediatric Cardiology
Published in: Pediatric Cardiology 2/2012

01-02-2012 | Case Report

Improvement and Defervescence of Persistent Fever After One Course of Intravenous Immunoglobulin in a Patient With Bacterial Infective Endocarditis

Authors: Musaab Ramsi, Rashed Durgham, Michael de Moor

Published in: Pediatric Cardiology | Issue 2/2012

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Excerpt

Infective endocarditis (IE) is a microbial infection of the endocardial surface of the heart. Because of the increased survival rate of children with congenital heart disease and other risk factors for IE, such as indwelling vascular lines, IV drug use, invasive procedures, and immunosuppressive disorders, there has been an increase in the population at risk for IE [1]. Conventional management of IE involves prolonged treatment with antimicrobial agents to eliminate the invading organisms that are harbored within heart vegetations. When positive blood cultures persist despite proper medical regimens, surgical intervention is indicated to remove the infected vegetations [1]. …
Literature
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Baddour LM, Wilson WR, Bayer AS et al (2005) Infective endocarditis: Diagnosis, antimicrobial therapy, management of complications: A statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, Kawasaki Disease, Council on Cardiovascular Disease in the Young, the Councils on Clinical Cardiology, Stroke, Cardiovascular Surgery, Anesthesia, American Heart Association: Endorsed by the Infectious Diseases Society of America. Circulation 111(23):394–434CrossRef
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Bayer AS, Theofilopoulos AN (1989) Immune complexes in infective endocarditis. Semin Immunopathol 11:457–469
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Blumberg EA, Robbins N, Adimora A, Lowy FD (1992) Persistent fever in association with infective endocarditis. Clin Infect 15:983–990CrossRef
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Carson DA, Bayer AS, Eisenberg R, Lawrance S, Theofilopoulos A (1978) IgM rheumatoid factor in subacute bacterial endocarditis: Relationship to IgG rheumatoid factor and circulating immune complexes. Clin Exp Immunol 31:100PubMed
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Heffner JE (1997) Extra cardiac manifestations of bacterial endocarditis. West J Med 131:85–91
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Kerr Ma, Wilton E, Naama JK, Whaley K (1986) Circulating immune complexes associated with decreased complement-mediated inhibition of immune precipitation in sera from patient with bacterial endocarditis. Clin Exp Immunol 63:359PubMed
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Nast CC, Colodro IH, Cohen AH (1986) Splenic immune deposits in bacterial endocarditis. Clin Immunol Immunopathol 40:209–213PubMedCrossRef
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Schwenk HU, Baenkler HW (1979) Effect of gammaglobulin injection on circulating immune complexes in various diseases. Eur J Pediatr 131(1):43–48PubMedCrossRef
Metadata
Title
Improvement and Defervescence of Persistent Fever After One Course of Intravenous Immunoglobulin in a Patient With Bacterial Infective Endocarditis
Authors
Musaab Ramsi
Rashed Durgham
Michael de Moor
Publication date
01-02-2012
Publisher
Springer-Verlag
Published in
Pediatric Cardiology / Issue 2/2012
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-011-0138-y

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