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Pediatric Cardiology
Published in: Pediatric Cardiology 4/2005

01-08-2005

A Case of Myocardial Infarction with Sumatriptan Use

Authors: E. Erbilen, H. Ozhan, R. Akdemir, M. Yazici

Published in: Pediatric Cardiology | Issue 4/2005

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Abstract

Sumatriptan is widely used in the treatment of acute attacks of cluster headache. It is a serotonin-1 (5HT-1) agonist. Several studies have reported an association between sumatriptan use and myocardial infarction, possibly due to the generalized vasoconstrictive nature of this agent. We report a 16-year-old male patient presenting with acute inferior myocardial infarction after sumatriptan use without any known risk factors of coronary artery disease.
Literature
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Connor, HE, Fenuik, W, Humphrey, PP 19895-Hydroxy-tryptamine contracts human coronary arteries predominantly via 5-HT2 receptor activationEur J Pharmacol1619194PubMedCrossRef
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Kelly, KM 1995Cardiac arrest following use of sumatriptanNeurology4512111213PubMed
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Maclntyre, PD, Bhargava, B, Hogg, KJ, Gemmill, JD, Hillis, WS 1993Effect of subcutaneous sumatriptan, a selective 5HT1 agonist, on the systemic, pulmonary, and coronary circulationCirculation87401405
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Mueller, L, Gallagher, RM, Ciervo, CA 1996Vasospasm-induced myocardial infarction with sumatriptanHeadache3632931PubMedCrossRef
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O'Conner, P, Gladstone, P 1995Oral sumatriptan-associated transmural myocardial infarctionNeurology4522742276
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Ottervanger, JP, Paalman, HJ, Boxma, GL, Stricker, BH 1993Transmural myocardial infarction with sumatriptanLancet341861862PubMedCrossRef
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Ottervanger, JP, Stricker, BH 1995Cardiovascular adverse reactions to sumatriptan: cause for concern?CNS Drugs39098CrossRef
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Ottervanger, JP, Valkenburg, HA, Grobbee, DE, Stricker, BH 1997Characteristics and determinants of sumatriptan-associated chest painArch Neurol5413871392PubMed
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Visser, WH, Jaspers, NM, Vriend, RH, Ferrari, MD 1996Chest symptoms after sumatriptan: a two-year clinical practice review in 735 consecutive migraine patientsCephalalgia16554559PubMed
Metadata
Title
A Case of Myocardial Infarction with Sumatriptan Use
Authors
E. Erbilen
H. Ozhan
R. Akdemir
M. Yazici
Publication date
01-08-2005
Publisher
Springer-Verlag
Published in
Pediatric Cardiology / Issue 4/2005
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-004-0768-4

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