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Pediatric Cardiology
Published in: Pediatric Cardiology 4/2004

01-07-2004

Recombinant t-PA in Myocardial Ischemia After Switch Operation

Authors: A. Tzifa, U. Joashi, Z. Slavik

Published in: Pediatric Cardiology | Issue 4/2004

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Abstract

A well-recognized complication of the anatomic correction (arterial switch operation) of transposition of the great arteries is obstruction of the translocated coronary arteries. Myocardial reperfusion has previously been achieved by surgical revascularization or percutaneous balloon angioplasty. We report the case of a 3-month-old infant who suffered myocardial infarction 11 weeks after the arterial switch operation, in whom myocardial reperfusion was established following infusion of recombinant tissue-type plasminogen activator (Alteplase®).
Literature
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Allada, V, Jarmakani, JM, Yeatman, L 1991Percutaneous transluminal coronary angioplasty in an infant with coronary artery stenosis after arterial switch operation.Am Heart J12214641465CrossRefPubMed
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Day, R, Laks, H, Drinkwater, DC 1992The influence of coronary anatomy on the arterial switch operation in neonates.J Thorac Cardiovasc Surg104706712PubMed
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Farnoux, C, Camard, O, Pinquier, D,  et al. 1998Recombinant tissue-type plasminogen activator therapy of thrombosis in 16 neonates.J Pediatr133137140PubMed
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Hausdorf, G, Kampmann, C, Schneider, M 1995Coronary angioplasty for coronary stenosis after the arterial switch procedure.Am J Cardiol76621623CrossRefPubMed
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Heidbuchel, H, Tack, J, Vanneste, L, Ballet, A,  et al. 1994Significance of arrhythmias during the first 24 hours of acute myocardial infarction treated with alteplase and effect of early administration of a beta-blocker or a bradycardic agent on their incidence.Circulation8910511059PubMed
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Kennedy, LA, Drummond, WH, Knight, ME,  et al. 1990Successful treatment of neonatal aortic thrombosis with tissue plasminogen activator.J Pediatr116798801PubMed
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Manco-Johnson, MJ, Grabowski, EF, Hellgreen, M,  et al. 2002Recommendations for tPA thrombolysis in children. On behalf of the Scientific Subcommittee on Perinatal and Pediatric Thrombosis of the Scientific and Standardization Committee of the International Society of Thombosis and Haemostasis.Thromb Haemost88157158PubMed
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Pretre, R, Tamisier, D, Bonhoeffer, P,  et al. 2001Results of the arterial switch operation in neonates with transposed great arteries.Lancet35718261830CrossRefPubMed
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Metadata
Title
Recombinant t-PA in Myocardial Ischemia After Switch Operation
Authors
A. Tzifa
U. Joashi
Z. Slavik
Publication date
01-07-2004
Publisher
Springer-Verlag
Published in
Pediatric Cardiology / Issue 4/2004
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-003-0473-8

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