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Published in: European Journal of Plastic Surgery 5/2018

Open Access 01-10-2018 | Review

Color Doppler ultrasonography targeted reconstruction using pedicled perforator flaps—a systematic review and meta-analysis

Authors: Rami Mossad Ibrahim, Gudjon Leifur Gunnarsson, Javed Akram, Jens Ahm Sørensen, Jørn Bo Thomsen

Published in: European Journal of Plastic Surgery | Issue 5/2018

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Abstract

Background

Flaps are increasingly popularized in reconstructive surgery and there is need to test and increase their reliability. Color Doppler ultrasound has been stated to be valuable in flap planning. The aim of this study was to conduct a systematic review and meta-analysis of the literature of Color Doppler ultrasound targeted pedicled perforator flaps and provide information on outcomes and complication rates.

Method

A systematic review and meta-analysis were conducted for articles published until April 2017 in PubMed and Embase. We aimed to include randomized clinical trials, meta-analysis, prospective studies, case-control studies, and cohort studies written in English. We included studies where CDU was used to identify the perforator(s) prior to surgery. We evaluated the quality of the included studies using checklists recommended by the Cochrane group.

Results

From the initial 219 studies, only 12 studies using Color Doppler targeted pedicled perforator flaps in 252 cases met the inclusion and exclusion criteria. Eleven of these were case series and one a prospective study. The incidence of major complications was 8% (21/252) and minor complications was 14%, comprising of mostly necrosis 8% (24/252) and venous congestion 8% (21/252).

Conclusions

The reconstructive success rate following pedicled perforator flap reconstruction targeted by CDU appears to be high and the procedure provides a wide scope of applications and margin of safety. It is evident that the risk of venous congestion is 11 times greater in the lower extremities than the truncus, a finding that needs further attention in future studies.
Level of Evidence: Level IV, risk/prognostic study
Literature
1.
go back to reference Gunnarsson GL, Jackson IT (2014) Freestyle facial perforator flaps—a safe reconstructive option for moderate-sized facial defects. Eur J Plast Surg 37:315–318CrossRef Gunnarsson GL, Jackson IT (2014) Freestyle facial perforator flaps—a safe reconstructive option for moderate-sized facial defects. Eur J Plast Surg 37:315–318CrossRef
2.
go back to reference Gunnarsson GL, Tei T, Thomsen JB (2016) Color Doppler ultrasonography–targeted perforator mapping and angiosome-based flap reconstruction. Ann Plast Surg 77:464–468CrossRef Gunnarsson GL, Tei T, Thomsen JB (2016) Color Doppler ultrasonography–targeted perforator mapping and angiosome-based flap reconstruction. Ann Plast Surg 77:464–468CrossRef
3.
go back to reference Gunnarsson GL, Jackson IT (2015) The freestyle pedicle perforator flap: a new favorite for the reconstruction of moderate-sized defects of the torso and extremities. Eur J Plast Surg 38:31–36CrossRef Gunnarsson GL, Jackson IT (2015) The freestyle pedicle perforator flap: a new favorite for the reconstruction of moderate-sized defects of the torso and extremities. Eur J Plast Surg 38:31–36CrossRef
4.
go back to reference Higgins JP, Green S (2011) Cochrane handbook for systematic reviews of interventions. The Cochrane Collaboration, London Higgins JP, Green S (2011) Cochrane handbook for systematic reviews of interventions. The Cochrane Collaboration, London
5.
go back to reference Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JPA, Clarke M, Devereaux PJ, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol 62:e1–e34CrossRef Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JPA, Clarke M, Devereaux PJ, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol 62:e1–e34CrossRef
6.
go back to reference Zeng X, Zhang Y, Kwong JSW, Zhang C, Li S, Sun F, Niu Y, du L (2015) The methodological quality assessment tools for preclinical and clinical studies, systematic review and meta-analysis, and clinical practice guideline: a systematic review. J Evid Based Med 8:2–10CrossRef Zeng X, Zhang Y, Kwong JSW, Zhang C, Li S, Sun F, Niu Y, du L (2015) The methodological quality assessment tools for preclinical and clinical studies, systematic review and meta-analysis, and clinical practice guideline: a systematic review. J Evid Based Med 8:2–10CrossRef
7.
go back to reference Moga C, Guo B, Schopflocher D, Harstall C (2012) Development of a quality appraisal tool for case series studies using a modified Delphi technique. Edmont AB Instute Health Economics, Alberta Moga C, Guo B, Schopflocher D, Harstall C (2012) Development of a quality appraisal tool for case series studies using a modified Delphi technique. Edmont AB Instute Health Economics, Alberta
8.
go back to reference Schmidt FL, Oh I-S, Hayes TL (2009) Fixed- versus random-effects models in meta-analysis: model properties and an empirical comparison of differences in results. Br J Math Stat Psychol 62:97–128CrossRef Schmidt FL, Oh I-S, Hayes TL (2009) Fixed- versus random-effects models in meta-analysis: model properties and an empirical comparison of differences in results. Br J Math Stat Psychol 62:97–128CrossRef
9.
go back to reference Zang M, Yu S, Xu L et al (2015) Freestyle perforator-based propeller flap of medial arm for medial elbow reconstruction. Microsurgery 35:1–4CrossRef Zang M, Yu S, Xu L et al (2015) Freestyle perforator-based propeller flap of medial arm for medial elbow reconstruction. Microsurgery 35:1–4CrossRef
10.
go back to reference Hamdi M, Van Landuyt K, Monstrey S, Blondeel P (2004) Pedicled perforator flaps in breast reconstruction: a new concept. Br J Plast Surg 57:531–539CrossRef Hamdi M, Van Landuyt K, Monstrey S, Blondeel P (2004) Pedicled perforator flaps in breast reconstruction: a new concept. Br J Plast Surg 57:531–539CrossRef
11.
go back to reference Jacobs J, Børsen-koch M, Gunnarsson GL et al (2015) The versatile extended thoracodorsal artery perforator flap for breast reconstruction. Ann Plast Surg 77:1–5 Jacobs J, Børsen-koch M, Gunnarsson GL et al (2015) The versatile extended thoracodorsal artery perforator flap for breast reconstruction. Ann Plast Surg 77:1–5
12.
go back to reference Zang M, Yu S, Xu L, Zhao Z, Zhu S, Ding Q, Liu Y (2015) Intercostal artery perforator propeller flap for reconstruction of trunk defects following sarcoma resection. J Plast Reconstr Aesthet Surg 68:822–829CrossRef Zang M, Yu S, Xu L, Zhao Z, Zhu S, Ding Q, Liu Y (2015) Intercostal artery perforator propeller flap for reconstruction of trunk defects following sarcoma resection. J Plast Reconstr Aesthet Surg 68:822–829CrossRef
13.
go back to reference Dong K, Xu Y, Fan X, Xu LJ, Su XX, Long H, Xu LQ, He XQ (2014) Perforator pedicled propeller flaps for soft tissue coverage of lower leg and foot defects. Orthop Surg 6:42–46CrossRef Dong K, Xu Y, Fan X, Xu LJ, Su XX, Long H, Xu LQ, He XQ (2014) Perforator pedicled propeller flaps for soft tissue coverage of lower leg and foot defects. Orthop Surg 6:42–46CrossRef
14.
go back to reference Tos P, Innocenti M, Artiaco S, Battiston B (2011) Perforator-based propeller flaps treating loss of substance in the lower limb. J Orthopaed Traumatol 12:93–99CrossRef Tos P, Innocenti M, Artiaco S, Battiston B (2011) Perforator-based propeller flaps treating loss of substance in the lower limb. J Orthopaed Traumatol 12:93–99CrossRef
15.
go back to reference Pignatti M, Pasqualini M, Governa M, Bruti M, Rigotti G (2008) Propeller flaps for leg reconstruction. J Plast Reconstr Aesthet Surg 61:777–783CrossRef Pignatti M, Pasqualini M, Governa M, Bruti M, Rigotti G (2008) Propeller flaps for leg reconstruction. J Plast Reconstr Aesthet Surg 61:777–783CrossRef
16.
go back to reference Jakubietz R, Meffert RH, Jakubietz MG (2010) Reconstruction of soft tissue defects of the achilles tendon with rotation flaps, pedicled propeller flaps and free perforator flaps. Microsurgery 1:1–6 Jakubietz R, Meffert RH, Jakubietz MG (2010) Reconstruction of soft tissue defects of the achilles tendon with rotation flaps, pedicled propeller flaps and free perforator flaps. Microsurgery 1:1–6
17.
go back to reference Moscatiello F, Carrera A, Moscatiello F et al (2007) The “propeller” distal anteromedial thigh perforator flap. Anatomic study and clinical applications. J Plast Reconstr Aesthet Surg 60:1323–1330CrossRef Moscatiello F, Carrera A, Moscatiello F et al (2007) The “propeller” distal anteromedial thigh perforator flap. Anatomic study and clinical applications. J Plast Reconstr Aesthet Surg 60:1323–1330CrossRef
18.
go back to reference Innocenti M, Baldrighi C, Delcroix L, Adani R (2009) Local perforator flaps in soft tissue reconstruction of the upper limb. Handchir Mikrochir Plast Chir 41:315–321CrossRef Innocenti M, Baldrighi C, Delcroix L, Adani R (2009) Local perforator flaps in soft tissue reconstruction of the upper limb. Handchir Mikrochir Plast Chir 41:315–321CrossRef
19.
go back to reference Umemoto Y, Adachi Y, Ebisawa K (2005) The sural artery perforator flap for coverage of defects of the knee and tibia. Scand J Plast Reconstr Surg Hand Surg 39:209–213CrossRef Umemoto Y, Adachi Y, Ebisawa K (2005) The sural artery perforator flap for coverage of defects of the knee and tibia. Scand J Plast Reconstr Surg Hand Surg 39:209–213CrossRef
20.
go back to reference Sisti A, D’Aniello C, Fortezza L, Tassinari J, Cuomo R et al (2016) Propeller flaps: a literature review. In Vivo (Brooklyn) 30:351–373PubMed Sisti A, D’Aniello C, Fortezza L, Tassinari J, Cuomo R et al (2016) Propeller flaps: a literature review. In Vivo (Brooklyn) 30:351–373PubMed
21.
go back to reference Paik J, Pyon J-K (2016) Risk factor analysis of freestyle propeller flaps. J Reconstr Microsurg 33:026–031CrossRef Paik J, Pyon J-K (2016) Risk factor analysis of freestyle propeller flaps. J Reconstr Microsurg 33:026–031CrossRef
22.
go back to reference Jiga LP, Barac S, Taranu G, Blidisel A, Dornean V, Nistor A, Stoichitoiu T, Geishauser M, Ionac M (2010) The versatility of propeller flaps for lower limb reconstruction in patients with peripheral arterial obstructive disease: initial experience. Ann Plast Surg 64:193–197CrossRef Jiga LP, Barac S, Taranu G, Blidisel A, Dornean V, Nistor A, Stoichitoiu T, Geishauser M, Ionac M (2010) The versatility of propeller flaps for lower limb reconstruction in patients with peripheral arterial obstructive disease: initial experience. Ann Plast Surg 64:193–197CrossRef
23.
go back to reference Panse N, Sahasrabudhe P (2014) Free style perforator based propeller flaps: simple solutions for upper extremity reconstruction! Indian J Plast Surg 47:77–84CrossRef Panse N, Sahasrabudhe P (2014) Free style perforator based propeller flaps: simple solutions for upper extremity reconstruction! Indian J Plast Surg 47:77–84CrossRef
24.
go back to reference Matei I, Georgescu A, Chiroiu B et al (2008) Harvesting of forearm perforator flaps based on intraoperative vascular exploration: clinical experiences and literature review. Microsurgery 28:321–330CrossRef Matei I, Georgescu A, Chiroiu B et al (2008) Harvesting of forearm perforator flaps based on intraoperative vascular exploration: clinical experiences and literature review. Microsurgery 28:321–330CrossRef
25.
go back to reference Lethaus B, Loberg C, Kloss-Brandstätter A, Bartella AK, Steiner T, Modabber A, Hölzle F, Teichmann J (2017) Color duplex ultrasonography versus handheld Doppler to plan anterior lateral thigh flaps. Microsurgery 37:388–393CrossRef Lethaus B, Loberg C, Kloss-Brandstätter A, Bartella AK, Steiner T, Modabber A, Hölzle F, Teichmann J (2017) Color duplex ultrasonography versus handheld Doppler to plan anterior lateral thigh flaps. Microsurgery 37:388–393CrossRef
26.
go back to reference Cheng H-T, Lin F-Y, Chang SC-N (2013) Diagnostic efficacy of color Doppler ultrasonography in preoperative assessment of anterolateral thigh flap cutaneous perforators: an evidence-based review. Plast Reconstr Surg 131:471e–473eCrossRef Cheng H-T, Lin F-Y, Chang SC-N (2013) Diagnostic efficacy of color Doppler ultrasonography in preoperative assessment of anterolateral thigh flap cutaneous perforators: an evidence-based review. Plast Reconstr Surg 131:471e–473eCrossRef
27.
go back to reference Nanno M, Kodera N, Tomori Y, Hagiwara Y, Takai S (2017) Color Doppler ultrasound assessment for identifying perforator arteries of the second dorsal metacarpal flap. J Orthop Surg 25:230949901668474CrossRef Nanno M, Kodera N, Tomori Y, Hagiwara Y, Takai S (2017) Color Doppler ultrasound assessment for identifying perforator arteries of the second dorsal metacarpal flap. J Orthop Surg 25:230949901668474CrossRef
Metadata
Title
Color Doppler ultrasonography targeted reconstruction using pedicled perforator flaps—a systematic review and meta-analysis
Authors
Rami Mossad Ibrahim
Gudjon Leifur Gunnarsson
Javed Akram
Jens Ahm Sørensen
Jørn Bo Thomsen
Publication date
01-10-2018
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Plastic Surgery / Issue 5/2018
Print ISSN: 0930-343X
Electronic ISSN: 1435-0130
DOI
https://doi.org/10.1007/s00238-018-1435-y

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