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Published in: Neuroradiology 11/2020

01-11-2020 | Refracture | Review

Risk factors of cemented vertebral refracture after percutaneous vertebral augmentation: a systematic review and meta-analysis

Authors: Shiqi Zhu, Qingjun Su, Yaoshen Zhang, Zhencheng Sun, Peng Yin, Yong Hai

Published in: Neuroradiology | Issue 11/2020

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Abstract

To evaluate the risk factors of cemented vertebral refracture after percutaneous vertebral augmentation (PVA) for patients with osteoporotic vertebral compression fractures (OVCFs). We performed a literature search on cemented vertebral refracture after PVA using the PubMed, EMBASE, and Cochrane Library medical databases. The clinical data, including literature information, basic patient information, observational factors, and interventional factors, were extracted by two authors. The pooled results and related heterogeneity of each factor between the refracture group and the non-refracture group were evaluated using Review Manager software 5.35. A total of 3185 patients from 10 studies were included, with 195 patients in the refracture group and 2990 patients in the non-refracture group. The mean follow-up duration was 18.9 months. According to the meta-analysis, age, low bone marrow density (BMD), intravertebral cleft (IVC), high anterior vertebral height (AVH) restoration/high Cobb angle restoration, and low cement dose were the risk factors of cemented vertebral refracture after PVA. Our results showed that age, low BMD, IVC, high AVH restoration, high Cobb angle restoration, and low cement dose were the risk factors for cemented vertebral refracture after PVA.
Literature
1.
go back to reference Johnell O, Kanis JA (2006) An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int 17:1726–1733CrossRef Johnell O, Kanis JA (2006) An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int 17:1726–1733CrossRef
2.
go back to reference Ameis A, Randhawa K, Yu H, Côté P, Haldeman S, Chou R, Hurwitz EL, Nordin M, Wong JJ, Shearer HM, Taylor-Vaisey A (2018) The Global Spine Care Initiative: a review of reviews and recommendations for the non-invasive management of acute osteoporotic vertebral compression fracture pain in low- and middle-income communities. Eur Spine J 27:861–869CrossRef Ameis A, Randhawa K, Yu H, Côté P, Haldeman S, Chou R, Hurwitz EL, Nordin M, Wong JJ, Shearer HM, Taylor-Vaisey A (2018) The Global Spine Care Initiative: a review of reviews and recommendations for the non-invasive management of acute osteoporotic vertebral compression fracture pain in low- and middle-income communities. Eur Spine J 27:861–869CrossRef
3.
go back to reference Luthman S, Widén J, Borgström F (2018) Appropriateness criteria for treatment of osteoporotic vertebral compression fractures. Osteoporos Int 29:793–804CrossRef Luthman S, Widén J, Borgström F (2018) Appropriateness criteria for treatment of osteoporotic vertebral compression fractures. Osteoporos Int 29:793–804CrossRef
4.
go back to reference Heo DH, Chin DK, Yoon YS, Kuh SU (2009) Recollapse of previous vertebral compression fracture after percutaneous vertebroplasty. Osteoporos Int 20:473–480CrossRef Heo DH, Chin DK, Yoon YS, Kuh SU (2009) Recollapse of previous vertebral compression fracture after percutaneous vertebroplasty. Osteoporos Int 20:473–480CrossRef
5.
go back to reference Bae JS, Park JH, Kim KJ, Kim HS, Jang IT (2017) Analysis of risk factors for secondary new vertebral compression fracture following percutaneous vertebroplasty in patients with osteoporosis. World Neurosurg 99:387–394CrossRef Bae JS, Park JH, Kim KJ, Kim HS, Jang IT (2017) Analysis of risk factors for secondary new vertebral compression fracture following percutaneous vertebroplasty in patients with osteoporosis. World Neurosurg 99:387–394CrossRef
6.
go back to reference Villarraga ML, Bellezza AJ, Harrigan TP, Cripton PA, Kurtz SM, Edidin AA (2005) The biomechanical effects of kyphoplasty on treated and adjacent nontreated vertebral bodies. J Spinal Disord Tech 18:84–91CrossRef Villarraga ML, Bellezza AJ, Harrigan TP, Cripton PA, Kurtz SM, Edidin AA (2005) The biomechanical effects of kyphoplasty on treated and adjacent nontreated vertebral bodies. J Spinal Disord Tech 18:84–91CrossRef
7.
go back to reference Li Y, Guo D, Zhang S, Liang D, Yuan K, Mo G, Li D, Guo H, Tang Y, Luo P (2018) Risk factor analysis for re-collapse of cemented vertebrae after percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP). Int Orthop 42:2131–2139CrossRef Li Y, Guo D, Zhang S, Liang D, Yuan K, Mo G, Li D, Guo H, Tang Y, Luo P (2018) Risk factor analysis for re-collapse of cemented vertebrae after percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP). Int Orthop 42:2131–2139CrossRef
8.
go back to reference Oh HS, Kim TW, Kim HG, Park KH (2016) Gradual height decrease of augmented vertebrae after vertebroplasty at the thoracolumbar junction. Korean J Neurotrauma 12:18–21CrossRef Oh HS, Kim TW, Kim HG, Park KH (2016) Gradual height decrease of augmented vertebrae after vertebroplasty at the thoracolumbar junction. Korean J Neurotrauma 12:18–21CrossRef
9.
go back to reference Niu J, Zhou H, Meng Q, Shi J, Meng B, Yang H (2014) Factors affecting recompression of augmented vertebrae after successful percutaneous balloon kyphoplasty: a retrospective analysis. Acta Radiol 56:1380–1387CrossRef Niu J, Zhou H, Meng Q, Shi J, Meng B, Yang H (2014) Factors affecting recompression of augmented vertebrae after successful percutaneous balloon kyphoplasty: a retrospective analysis. Acta Radiol 56:1380–1387CrossRef
10.
go back to reference Kang S, Lee CW, Park NK, Kang T, Lim J, Cha KY, Kim JH (2011) Predictive risk factors for refracture after percutaneous vertebroplasty. Ann Rehabil Med 35:844–851CrossRef Kang S, Lee CW, Park NK, Kang T, Lim J, Cha KY, Kim JH (2011) Predictive risk factors for refracture after percutaneous vertebroplasty. Ann Rehabil Med 35:844–851CrossRef
11.
go back to reference Chen L, Hsieh M, Liao J, Lai P, Niu C, Fu T, Tsai T, Chen W (2011) Repeated percutaneous vertebroplasty for refracture of cemented vertebrae. Arch Orthop Trauma Surg 131:927–933CrossRef Chen L, Hsieh M, Liao J, Lai P, Niu C, Fu T, Tsai T, Chen W (2011) Repeated percutaneous vertebroplasty for refracture of cemented vertebrae. Arch Orthop Trauma Surg 131:927–933CrossRef
12.
go back to reference Kim Y, Rhyu K (2010) Recompression of vertebral body after balloon kyphoplasty for osteoporotic vertebral compression fracture. Eur Spine J 19:1907–1912CrossRef Kim Y, Rhyu K (2010) Recompression of vertebral body after balloon kyphoplasty for osteoporotic vertebral compression fracture. Eur Spine J 19:1907–1912CrossRef
13.
go back to reference Summa A, Crisi G, Cerasti D, Ventura E, Menozzi R, Ormitti F (2009) Refractures in cemented vertebrae after percutaneous vertebroplasty and pain relief after a second procedure: a retrospective analysis. Neuroradiol J 22:239–243CrossRef Summa A, Crisi G, Cerasti D, Ventura E, Menozzi R, Ormitti F (2009) Refractures in cemented vertebrae after percutaneous vertebroplasty and pain relief after a second procedure: a retrospective analysis. Neuroradiol J 22:239–243CrossRef
14.
go back to reference Lin WC, Lee YC, Lee CH, Kuo YL, Cheng YF, Lui CC, Cheng TT (2008) Refractures in cemented vertebrae after percutaneous vertebroplasty: a retrospective analysis. Eur Spine J 17:592–599CrossRef Lin WC, Lee YC, Lee CH, Kuo YL, Cheng YF, Lui CC, Cheng TT (2008) Refractures in cemented vertebrae after percutaneous vertebroplasty: a retrospective analysis. Eur Spine J 17:592–599CrossRef
15.
go back to reference Lin W, Lu C, Chen H, Wang H, Yu C, Wu R, Cheng Y, Lui C (2010) The impact of preoperative magnetic resonance images on outcome of cemented vertebrae. Eur Spine J 19:1899–1906CrossRef Lin W, Lu C, Chen H, Wang H, Yu C, Wu R, Cheng Y, Lui C (2010) The impact of preoperative magnetic resonance images on outcome of cemented vertebrae. Eur Spine J 19:1899–1906CrossRef
16.
go back to reference Diel P, Freiburghaus L, Roder C, Benneker LM, Popp A, Perler G, Heini PF (2012) Safety, effectiveness and predictors for early reoperation in therapeutic and prophylactic vertebroplasty: short-term results of a prospective case series of patients with osteoporotic vertebral fractures. Eur Spine J 21(Suppl 6):S792–S799CrossRef Diel P, Freiburghaus L, Roder C, Benneker LM, Popp A, Perler G, Heini PF (2012) Safety, effectiveness and predictors for early reoperation in therapeutic and prophylactic vertebroplasty: short-term results of a prospective case series of patients with osteoporotic vertebral fractures. Eur Spine J 21(Suppl 6):S792–S799CrossRef
17.
go back to reference Guarnieri G, Ambrosanio G, Pezzullo MG, Zeccolini F, Vassallo P, Galasso R, Lavanga A, Muto M (2009) Management of vertebral re-fractures after vertebroplasty in osteoporotic patients. Interv Neuroradiol 15:153–157CrossRef Guarnieri G, Ambrosanio G, Pezzullo MG, Zeccolini F, Vassallo P, Galasso R, Lavanga A, Muto M (2009) Management of vertebral re-fractures after vertebroplasty in osteoporotic patients. Interv Neuroradiol 15:153–157CrossRef
18.
go back to reference Yu W, Xu W, Jiang X, Liang JW (2018) Risk factors for recollapse of the augmented vertebrae after percutaneous vertebral augmentation: a systematic review and meta-analysis. World Neurosurg 111:119–129CrossRef Yu W, Xu W, Jiang X, Liang JW (2018) Risk factors for recollapse of the augmented vertebrae after percutaneous vertebral augmentation: a systematic review and meta-analysis. World Neurosurg 111:119–129CrossRef
19.
go back to reference Kanazawa I, Sugimoto T (2015) Analysis of musculoskeletal systems and their diseases. Integrated treatments for osteoporosis toward harmony of bone and muscle. Clin Calcium 25:1109–1115PubMed Kanazawa I, Sugimoto T (2015) Analysis of musculoskeletal systems and their diseases. Integrated treatments for osteoporosis toward harmony of bone and muscle. Clin Calcium 25:1109–1115PubMed
20.
go back to reference Center JR, Bliuc D, Nguyen ND, Nguyen TV, Eisman JA (2011) Osteoporosis medication and reduced mortality risk in elderly women and men. J Clin Endocrinol Metab 96:1006–1014CrossRef Center JR, Bliuc D, Nguyen ND, Nguyen TV, Eisman JA (2011) Osteoporosis medication and reduced mortality risk in elderly women and men. J Clin Endocrinol Metab 96:1006–1014CrossRef
21.
go back to reference Li Z, Liu T, Yin P, Wang Y, Liao S, Zhang S, Su Q, Hai Y (2019) The therapeutic effects of percutaneous kyphoplasty on osteoporotic vertebral compression fractures with or without intravertebral cleft. Int Orthop 43:359–365CrossRef Li Z, Liu T, Yin P, Wang Y, Liao S, Zhang S, Su Q, Hai Y (2019) The therapeutic effects of percutaneous kyphoplasty on osteoporotic vertebral compression fractures with or without intravertebral cleft. Int Orthop 43:359–365CrossRef
22.
go back to reference Nieuwenhuijse MJ, van Rijswijk CSP, van Erkel AR, Dijkstra SPD (2012) The Intravertebral cleft in painful long-standing osteoporotic vertebral compression fractures treated with percutaneous vertebroplasty. Spine 37:974–981CrossRef Nieuwenhuijse MJ, van Rijswijk CSP, van Erkel AR, Dijkstra SPD (2012) The Intravertebral cleft in painful long-standing osteoporotic vertebral compression fractures treated with percutaneous vertebroplasty. Spine 37:974–981CrossRef
23.
go back to reference Chongyan W, Zhang X, Li S, Liu J, Shan Z, Wang J, Chen J, Fan S, Zhao F (2018) Mechanism of formation of intravertebral clefts in osteoporotic vertebral compression fractures: an in vitro biomechanical study. Spine J 18:2297–2301CrossRef Chongyan W, Zhang X, Li S, Liu J, Shan Z, Wang J, Chen J, Fan S, Zhao F (2018) Mechanism of formation of intravertebral clefts in osteoporotic vertebral compression fractures: an in vitro biomechanical study. Spine J 18:2297–2301CrossRef
24.
go back to reference Jammy GR, Boudreau RM, Singh T, Sharma PK, Ensrud K, Zmuda JM, Reddy PS, Newman AB, Cauley JA (2018) Volumetric bone mineral density (vBMD), bone structure, and structural geometry among rural South Indian, US Caucasian, and afro-Caribbean older men. Arch Osteoporos 13:1–9CrossRef Jammy GR, Boudreau RM, Singh T, Sharma PK, Ensrud K, Zmuda JM, Reddy PS, Newman AB, Cauley JA (2018) Volumetric bone mineral density (vBMD), bone structure, and structural geometry among rural South Indian, US Caucasian, and afro-Caribbean older men. Arch Osteoporos 13:1–9CrossRef
25.
go back to reference Syed MI, Patel NA, Jan S, Shaikh A, Grunden B, Morar K (2006) Symptomatic refractures after vertebroplasty in patients with steroid-induced osteoporosis. AJNR Am J Neuroradiol 27:1938–1943PubMed Syed MI, Patel NA, Jan S, Shaikh A, Grunden B, Morar K (2006) Symptomatic refractures after vertebroplasty in patients with steroid-induced osteoporosis. AJNR Am J Neuroradiol 27:1938–1943PubMed
26.
go back to reference Huntoon EA, Schmidt CK, Sinaki M (2008) Significantly fewer refractures after vertebroplasty in patients who engage in back-extensor-strengthening exercises. Mayo Clin Proc 83:54–57CrossRef Huntoon EA, Schmidt CK, Sinaki M (2008) Significantly fewer refractures after vertebroplasty in patients who engage in back-extensor-strengthening exercises. Mayo Clin Proc 83:54–57CrossRef
27.
go back to reference Zhang J, Fan Y, He X, Du J, Hao D (2019) Bracing after percutaneous vertebroplasty for thoracolumbar osteoporotic vertebral compression fractures was not effective. Clin Interv Aging 14:265–270CrossRef Zhang J, Fan Y, He X, Du J, Hao D (2019) Bracing after percutaneous vertebroplasty for thoracolumbar osteoporotic vertebral compression fractures was not effective. Clin Interv Aging 14:265–270CrossRef
Metadata
Title
Risk factors of cemented vertebral refracture after percutaneous vertebral augmentation: a systematic review and meta-analysis
Authors
Shiqi Zhu
Qingjun Su
Yaoshen Zhang
Zhencheng Sun
Peng Yin
Yong Hai
Publication date
01-11-2020
Publisher
Springer Berlin Heidelberg
Keyword
Refracture
Published in
Neuroradiology / Issue 11/2020
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI
https://doi.org/10.1007/s00234-020-02495-9

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