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Neuroradiology
Published in: Neuroradiology 6/2013

01-06-2013 | CONTINUING EDUCATION

Cerebral microbleeds: a guide to detection and clinical relevance in different disease settings

Authors: Andreas Charidimou, Anant Krishnan, David J. Werring, H. Rolf Jäger

Published in: Neuroradiology | Issue 6/2013

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Abstract

Cerebral microbleeds have emerged as an important new imaging marker of cerebral small vessel disease. With the development of MRI techniques that are exquisitely sensitive to paramagnetic blood products, such as T2*-weighted gradient-recalled echo and susceptibility-weighted sequences, microbleeds have been detected in ever-increasing numbers of patients in stroke and cognitive clinics, as well as in healthy older people and in a variety of other rarer diseases and syndromes. Detection of cerebral microbleeds has clinical implications with respect to the diagnosis of the underlying small vessel disease, the safety of antithrombotic use, and the risk of symptomatic intracerebral haemorrhage, cognitive impairment and dementia. This article provides a guide to the detection and clinical relevance of cerebral microbleeds in different conditions based on a comprehensive review of the literature and own findings in research and clinical practice.
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Metadata
Title
Cerebral microbleeds: a guide to detection and clinical relevance in different disease settings
Authors
Andreas Charidimou
Anant Krishnan
David J. Werring
H. Rolf Jäger
Publication date
01-06-2013
Publisher
Springer-Verlag
Published in
Neuroradiology / Issue 6/2013
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI
https://doi.org/10.1007/s00234-013-1175-4

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