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01-02-2004 | Diagnostic Neuroradiology

MR perfusion imaging in proliferative angiopathy

Authors: D. Ducreux, J. F. Meder, D. Fredy, J. Bittoun, P. Lasjaunias

Published in: Neuroradiology | Issue 2/2004

Abstract

Seizures, which may be the main expression of cerebral arteriovenous malformations (CAVM) can be difficult to control medically. Our goal was to use perfusion-weighted imaging (PWI) in correlation with clinical data to detect abnormal areas of the cerebrum related to a particular type of CAVM (proliferative angiopathy) and to study the pathophysiology. We use PWI, with a bolus injection of contrast medium, to investigate seven patients with proliferative angiopathy and fits producing language disturbance. Perfusion parameters were calculated using the first-pass moment theory. Five patients had perimalformative and/or contralateral abnormal areas with relative hyperperfusion (cerebral blood volume +20.7±16.2%, blood flow 92.5±68.8 ml/min/100 g). Areas of hypoperfusion and venous congestion were detected in two patients. One patient who underwent MRI after a severe focal deficit had no significant haemodynamic abnormality.

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Title: MR perfusion imaging in proliferative angiopathy
Authors: D. Ducreux
J. F. Meder
D. Fredy
J. Bittoun
P. Lasjaunias
Publication date: 01-02-2004
Publisher: Springer-Verlag
Published in: Neuroradiology / Issue 2/2004
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI: https://doi.org/10.1007/s00234-003-1045-6

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