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Osteoporosis International
Published in: Osteoporosis International 4/2014

01-04-2014 | Original Article

Does lean tissue mass accrual during adolescence influence bone structural strength at the proximal femur in young adulthood?

Authors: S. A. Jackowski, J. L. Lanovaz, C. Van Oort, A. D. G. Baxter-Jones

Published in: Osteoporosis International | Issue 4/2014

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Abstract

Summary

The purpose of this study was to identify whether young adult bone structural strength at the hip is associated with adolescent lean tissue mass (LTM) accrual. It was observed that those individuals who accrued more LTM from adolescence to adulthood had significantly greater adult bone structural strength at the hip.

Introduction

The purpose of this study was to identify whether young adult bone cross-sectional area (CSA), section modulus (Z), and outer diameter (OD) at the hip were associated with adolescent LTM accrual.

Methods

One hundred three young adult participants (55 males, 48 females) were tertiled into adolescent LTM accrual groupings. LTM accrual was assessed by serial measures using dual energy X-ray absorptiometry (DXA) from adolescence to young adulthood (21.3 ± 1.3 years). CSA, Z, and OD at the narrow neck (NN) and femoral shaft (S) sites of the proximal femur were assessed in young adulthood (21.3 ± 4.5 years), using hip structural analysis. Group differences were assessed using an analysis of covariance, controlling for adult height, weight, sex, and physical activity levels.

Results

It was found that individuals with higher adjusted adolescent LTM accrual had significantly greater adult adjusted values of NNCSA (2.49 ± 0.06 vs 2.77 ± 0.07 cm2), NN Z (1.18 ± 0.04 vs 1.37 ± 0.04 cm3), NN OD (3.07 ± 0.04 vs 3.21 ± 0.04 cm), SCSA (3.45 ± 0.08 vs 3.88 ± 0.09 cm3), and SZ (1.77 ± 0.05 vs 2.00 ± 0.05 cm3) than individuals with lower LTM accrual (p < 0.05).

Conclusions

These findings suggest that the amount of LTM accrued from adolescence to young adulthood has a positive influence on adult bone structural strength at the proximal femur.
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Metadata
Title
Does lean tissue mass accrual during adolescence influence bone structural strength at the proximal femur in young adulthood?
Authors
S. A. Jackowski
J. L. Lanovaz
C. Van Oort
A. D. G. Baxter-Jones
Publication date
01-04-2014
Publisher
Springer London
Published in
Osteoporosis International / Issue 4/2014
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-013-2592-2

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