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International Urogynecology Journal

Published in:

01-05-2010 | Original Article

Porcine skin collagen implants for anterior vaginal wall prolapse: a randomised prospective controlled study

Authors: Ulla Hviid, Thomas Vauvert F. Hviid, Martin Rudnicki

Published in: International Urogynecology Journal | Issue 5/2010

Abstract

Introduction and hypothesis

The effect of a Pelvicol® graft compared with a conventional anterior vaginal repair was evaluated in this randomised controlled study.

Methods

Only patients with a stage II or higher (Ba ≥ −1) defect were included.

Results

Thirty-one patients were allocated to a conventional anterior repair; 30 to Pelvicol® graft. At 12 months follow-up, four patients among controls (15%) and two in the graft group (7%) had objective recurrence. Among controls, the difference at 3 months follow-up in Ba was 6.0 cm when compared with the position of Ba prior to surgery. In the graft group, the difference was 7.0 cm (P < 0.05). This difference was still present at 12 months follow-up (6.0 vs. 7.0 cm; P < 0.05).

Conclusions

The implantation of a Pelvicol® graft does not improve the POP-Q stage.

Olsen AL, Smith VJ, Bergstrom JO, Colling JC, Clark AL (2001) Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence. Obstet Gynecol 89:501–506CrossRef

Nguyen JK (2001) Current concepts in the diagnosis and surgical repair of anterior vaginal prolapse due to paravaginal defects. Obstet Gynecol Surv 56:239–246CrossRefPubMed

Richardson AC, Edmonds PB, Williams NL (1981) Treatment of stress urinary incontinence due to paravaginal fascial defect. Obstet Gynecol 57:357–362PubMed

Delancey JO (2002) Fascial and muscular abnormalities in women with urethral hypermobility and anterior vaginal wall prolapse. Am J Obstet Gynecol 187:93–99CrossRefPubMed

Tunn R, Rieprich M, Kaufmann O, Gauruder-Burmester A, Beyersdorff D (2005) Morphology of the suburethral pubocervical fascia in women with stress urinary incontinence: a comparison of histologic and MRI findings. Int Urogynecol J Pelvic Floor Dysfunct 16:480–486CrossRefPubMed

Morse AN, O’Dell KK, Hovard AE, Baker SP, Aronson MP, Young SB (2007) Midline anterior repair alone vs anterior repair plus vaginal paravaginal repair: a comparison of anatomic and quality of life outcome. Int Urogynecol J 18:245–249CrossRef

Weber AM, Walters MD, Piedmonte MR, Ballard LA (2001) Anterior colporrhaphy: a randomized trial of three surgical techniques. Am J Obstet Gynecol 185:1299–1304CrossRefPubMed

Sand PK, Koduri S, Lobel RW, Winkler HA, Tomezsko J, Culligan PJ, Goldberg R (2001) Prospective randomized trial of polyglactin 910 mesh to prevent recurrence of cystoceles and rectoceles. Am J Obstet Gynecol 184:1357–1362CrossRefPubMed

Raz S, Little NA, Juma S, Sussman EM (1991) Repair of severe anterior vaginal wall prolapse (grade IV cystourethrocele). J Urol 146:988–992PubMed

10.

Handel LN, Frenkl TL, Kim YH (2007) Results of cystocele repair: a comparison of traditional anterior colporrhaphy, polypropylene mesh and porcine dermis. J Urol 178:153–156CrossRefPubMed

11.

Nguyen JN, Burchette RJ (2008) Outcome after anterior vaginal prolapse repair. Obstet Gynecol 111:981–988

12.

Altman D, Väyrynen T, Engh ME, Axelsen S, Falconer C (2008) Short-term outcome after transvaginal mesh repair of pelvic organ prolapse. Int Urogynecol J 19:787–793CrossRef

13.

Meschia M, Pifarotti P, Bernasconi F, Magatti F, Riva D, Kocjancic E (2007) Porcine skin collagen implants to prevent anterior vaginal wall prolapse recurrence: a multicenter, randomized study. J Urol 177:192–195CrossRefPubMed

14.

David-Montefiore E, Barranger E, Dubernard G, Detchev R, Nizard V, Daraï E (2005) Treatment of genital prolapse by hammock using porcine skin collagen implant (Pelvicol). Urology 66(6):1314–1318CrossRefPubMed

15.

de Tayrac R, Devoldere G, Renaudie J, Villard P, Guilbaud O, Eglin G, French Ugytex Study Group (2007) Prolapse repair by vaginal route using a new protected low-weight polypropylene mesh: 1-year functional and anatomical outcome in a prospective multicentre study. Int Urogynecol J Pelvic Floor Dysfunct 18:251–256CrossRefPubMed

16.

Maher C, Baessler K, Glazener CM, Adams EJ, Hagen S (2008) Surgical management of pelvic organ prolapse in women: a short version Cochrane review. Neurourol Urodyn 27:3–12CrossRefPubMed

17.

Rudnicki M (2007) Biomesh (Pelvicol) erosion following repair of anterior vaginal wall prolapse. Int Urogynecol J Pelvic Floor Dysfunct 18:693–695CrossRefPubMed

Title: Porcine skin collagen implants for anterior vaginal wall prolapse: a randomised prospective controlled study
Authors: Ulla Hviid
Thomas Vauvert F. Hviid
Martin Rudnicki
Publication date: 01-05-2010
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue 5/2010
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-009-1018-3

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Porcine skin collagen implants for anterior vaginal wall prolapse: a randomised prospective controlled study

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

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