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Published in: Knee Surgery, Sports Traumatology, Arthroscopy 10/2016

01-10-2016 | Knee

Articulated spacer provides long-term knee improvement after two-stage reimplantation

Authors: Michele Vasso, Chiara Del Regno, Katia Corona, Rocco D’Apolito, Alfredo Schiavone Panni

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 10/2016

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Abstract

Purpose

The purpose of this study was to determine the long-term outcome in patients who underwent two-stage reimplantation with an articulated spacer following a chronic periprosthetic knee infection. The hypothesis was that the use of an articulated spacer provides significant improvement of clinical results and knee functionality through a long follow-up period, and therefore a durable revision TKA.

Methods

Forty-six consecutive patients (46 knees) who underwent two-stage reimplantation with an articulated spacer for a chronic periprosthetic knee infection were retrospectively analysed. An articulated cement spacer, moulded in surgery room, was implanted in all cases. Patients were followed for a median period of 12 (range 6–16) years, and no patients were lost to follow-up. Patients were assessed preoperatively and postoperatively through the IKS knee and function scores and ROM.

Results

Two-stage reimplantation was successful in controlling the infection in 91.3 % of patients. In the 42 patients with a successful two-stage revision, the median IKS knee and function scores were 36 (range 16–56) points and 25 (range 15–35) points, respectively, before the operation, and 76 (range 52–94) points and 70 (range 55–90) points (p < 0.001) at the last follow-up. The median ROM increased from 80 (range 60–110) degrees preoperatively to 115 (range 100–128) degrees (p < 0.01) at the last follow-up.

Conclusions

Two-stage septic revision with an articulated cement spacer provided a significant long-term improvement of preoperative clinical and functional knee scores and therefore a durable revision TKA.

Level of evidence

Retrospective case series, Level IV.
Literature
1.
go back to reference Babis GC, Sakellariou VI, Pantos PG, Sasalos GG, Stavropoulos NA (2015) Two-stage revision protocol in multidrug resistant periprosthetic infection following total hip arthroplasty using a long interval between stages. J Arthroplasty 30:1602–1606CrossRefPubMed Babis GC, Sakellariou VI, Pantos PG, Sasalos GG, Stavropoulos NA (2015) Two-stage revision protocol in multidrug resistant periprosthetic infection following total hip arthroplasty using a long interval between stages. J Arthroplasty 30:1602–1606CrossRefPubMed
2.
go back to reference Castelli CC, Gotti V, Ferrari R (2014) Two-stage treatment of infected total knee arthroplasty: two to thirteen year experience using an articulating preformed spacer. Int Orthop 38:405–412CrossRefPubMedPubMedCentral Castelli CC, Gotti V, Ferrari R (2014) Two-stage treatment of infected total knee arthroplasty: two to thirteen year experience using an articulating preformed spacer. Int Orthop 38:405–412CrossRefPubMedPubMedCentral
3.
go back to reference De Martino I, De Santis V, Sculco PK, D’Apolito R, Assini JB, Gasparini G (2015) Tantalum cones provide durable mid-term fixation in revision tka. Clin Orthop Relat Res 473:3176–3182CrossRefPubMedPubMedCentral De Martino I, De Santis V, Sculco PK, D’Apolito R, Assini JB, Gasparini G (2015) Tantalum cones provide durable mid-term fixation in revision tka. Clin Orthop Relat Res 473:3176–3182CrossRefPubMedPubMedCentral
4.
go back to reference Drexler M, DwyerT Kuzyk PRT, Kosashvilli Y, Abolghasemian M, Regev GJ, Kadar A, Rutenberg TF, Backstein D (2015) The results of two-stage revision TKA using Ceftazidime-Vancomycin-impregnated cement articulating spacers in Tsukayama Type II periprosthetic joint infections. Knee Surg Sports Traumatol Arthrosc. doi:10.1007/s00167-015-3753-y Drexler M, DwyerT Kuzyk PRT, Kosashvilli Y, Abolghasemian M, Regev GJ, Kadar A, Rutenberg TF, Backstein D (2015) The results of two-stage revision TKA using Ceftazidime-Vancomycin-impregnated cement articulating spacers in Tsukayama Type II periprosthetic joint infections. Knee Surg Sports Traumatol Arthrosc. doi:10.​1007/​s00167-015-3753-y
5.
go back to reference Engh GA, Parks NL (1997) The management of bone defects in revision total knee arthroplasty. Instr Course Lect 46:227–236PubMed Engh GA, Parks NL (1997) The management of bone defects in revision total knee arthroplasty. Instr Course Lect 46:227–236PubMed
6.
go back to reference Gooding CR, Masri BA, Duncan CP, Greidanus NV, Garbuz DS (2011) Durable infection control and function with the PROSTALAC spacer in two-stage revision for infected knee arthroplasty. Clin Orthop Relat Res 469:985–993CrossRefPubMed Gooding CR, Masri BA, Duncan CP, Greidanus NV, Garbuz DS (2011) Durable infection control and function with the PROSTALAC spacer in two-stage revision for infected knee arthroplasty. Clin Orthop Relat Res 469:985–993CrossRefPubMed
7.
go back to reference Hofmann AA, Goldberg T, Tanner AM, Kurtin SM (2005) Treatment of infected total knee arthroplasty using an articulating spacer: 2- to 12-year experience. Clin Orthop Relat Res 430:125–131CrossRefPubMed Hofmann AA, Goldberg T, Tanner AM, Kurtin SM (2005) Treatment of infected total knee arthroplasty using an articulating spacer: 2- to 12-year experience. Clin Orthop Relat Res 430:125–131CrossRefPubMed
8.
go back to reference Insall JN, Dorr LD, Scott RD, Scott WN (1989) Rationale of the Knee Society clinical rating system. Clin Orthop Relat Res 248:13–14PubMed Insall JN, Dorr LD, Scott RD, Scott WN (1989) Rationale of the Knee Society clinical rating system. Clin Orthop Relat Res 248:13–14PubMed
9.
go back to reference Jaekel DJ, Day JS, Klein GR, Levine H, Parvizi J, Kurtz SM (2012) Do dynamic cement-on-cement knee spacers provide better function and activity during two-stage exchange? Clin Orthop Relat Res 470:2599–2604CrossRefPubMedPubMedCentral Jaekel DJ, Day JS, Klein GR, Levine H, Parvizi J, Kurtz SM (2012) Do dynamic cement-on-cement knee spacers provide better function and activity during two-stage exchange? Clin Orthop Relat Res 470:2599–2604CrossRefPubMedPubMedCentral
10.
go back to reference Johnson AJ, Sayeed SA, Naziri Q, Khanuja HS, Mont MA (2012) Minimizing dynamic knee spacer complications in infected revision arthroplasty. Clin Orthop Relat Res 470:220–227CrossRefPubMed Johnson AJ, Sayeed SA, Naziri Q, Khanuja HS, Mont MA (2012) Minimizing dynamic knee spacer complications in infected revision arthroplasty. Clin Orthop Relat Res 470:220–227CrossRefPubMed
11.
go back to reference Kalore NV, Maheshwari A, Sharma A, Cheng E, Gioe TJ (2012) Is there a preferred articulating spacer technique for infected knee arthroplasty? A preliminary study. Clin Orthop Relat Res 470:228–235CrossRefPubMed Kalore NV, Maheshwari A, Sharma A, Cheng E, Gioe TJ (2012) Is there a preferred articulating spacer technique for infected knee arthroplasty? A preliminary study. Clin Orthop Relat Res 470:228–235CrossRefPubMed
12.
go back to reference Kurd MF, Ghanem E, Steinbrecher J, Parvizi J (2010) Two-stage exchange knee arthroplasty: does resistance of the infecting organism influence the outcome? Clin Orthop Relat Res 468:2060–2066CrossRefPubMedPubMedCentral Kurd MF, Ghanem E, Steinbrecher J, Parvizi J (2010) Two-stage exchange knee arthroplasty: does resistance of the infecting organism influence the outcome? Clin Orthop Relat Res 468:2060–2066CrossRefPubMedPubMedCentral
13.
go back to reference Logoluso N, Nardo A, Anasetti F, Scarponi S, Romanò CL (2016) Does knee revision after an articulated spacer implant provide normal gait restoration? Knee Surg Sports Traumatol Arthrosc 24:267–272CrossRefPubMed Logoluso N, Nardo A, Anasetti F, Scarponi S, Romanò CL (2016) Does knee revision after an articulated spacer implant provide normal gait restoration? Knee Surg Sports Traumatol Arthrosc 24:267–272CrossRefPubMed
14.
go back to reference McPherson EJ, Patzakis MJ, Gross JE, Holtom PD, Song M, Dorr LD (1997) Infected total knee arthroplasty. Two-stage reimplantation with a gastrocnemius rotational flap. Clin Orthop Relat Res 341:73–81CrossRefPubMed McPherson EJ, Patzakis MJ, Gross JE, Holtom PD, Song M, Dorr LD (1997) Infected total knee arthroplasty. Two-stage reimplantation with a gastrocnemius rotational flap. Clin Orthop Relat Res 341:73–81CrossRefPubMed
15.
go back to reference Panni AS, Vasso M, Cerciello S (2013) Modular augmentation in revision total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 21:2837–2843CrossRefPubMed Panni AS, Vasso M, Cerciello S (2013) Modular augmentation in revision total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 21:2837–2843CrossRefPubMed
16.
go back to reference Romanò CL, Gala L, Logoluso N, Romanò D, Drago L (2012) Two-stage revision of septic knee prosthesis with articulating knee spacers yields better infection eradication rate than one-stage or two-stage revision with static spacers. Knee Surg Sports Traumatol Arthrosc 20:2445–2453CrossRefPubMed Romanò CL, Gala L, Logoluso N, Romanò D, Drago L (2012) Two-stage revision of septic knee prosthesis with articulating knee spacers yields better infection eradication rate than one-stage or two-stage revision with static spacers. Knee Surg Sports Traumatol Arthrosc 20:2445–2453CrossRefPubMed
17.
go back to reference Siddiqui MM, Lo NN, Ab Rahman S, Chin PL, Chia SL, Yeo SJ (2013) Two-year outcome of early deep MRSA infections after primary total knee arthroplasty: a joint registry review. J Arthroplasty 28:44–48CrossRefPubMed Siddiqui MM, Lo NN, Ab Rahman S, Chin PL, Chia SL, Yeo SJ (2013) Two-year outcome of early deep MRSA infections after primary total knee arthroplasty: a joint registry review. J Arthroplasty 28:44–48CrossRefPubMed
18.
go back to reference Silvestre A, Almeida F, Renovell P, Morante E, López R (2013) Revision of infected total knee arthroplasty: two-stage reimplantation using an antibiotic-impregnated static spacer. Clin Orthop Surg 5:180–187CrossRefPubMedPubMedCentral Silvestre A, Almeida F, Renovell P, Morante E, López R (2013) Revision of infected total knee arthroplasty: two-stage reimplantation using an antibiotic-impregnated static spacer. Clin Orthop Surg 5:180–187CrossRefPubMedPubMedCentral
19.
go back to reference Struelens B, Claes S, Bellemans J (2013) Spacer-related problems in two-stage revision knee arthroplasty. Acta Orthop Belg 79:422–426PubMed Struelens B, Claes S, Bellemans J (2013) Spacer-related problems in two-stage revision knee arthroplasty. Acta Orthop Belg 79:422–426PubMed
21.
go back to reference Vasso M, Schiavone Panni A, De Martino I, Gasparini G (2016) Prosthetic knee infection by resistant bacteria: the worst-case scenario. Knee Surg Sports Traumatol Arthrosc. doi:10.1007/s00167-016-4010-8 Vasso M, Schiavone Panni A, De Martino I, Gasparini G (2016) Prosthetic knee infection by resistant bacteria: the worst-case scenario. Knee Surg Sports Traumatol Arthrosc. doi:10.​1007/​s00167-016-4010-8
22.
go back to reference Wan Z, Karim A, Momaya A, Incavo SJ, Mathis KB (2012) Preformed articulating knee spacers in 2-stage total knee revision arthroplasty: minimum 2-year follow-up. J Arthroplasty 27:1469–1473CrossRefPubMed Wan Z, Karim A, Momaya A, Incavo SJ, Mathis KB (2012) Preformed articulating knee spacers in 2-stage total knee revision arthroplasty: minimum 2-year follow-up. J Arthroplasty 27:1469–1473CrossRefPubMed
Metadata
Title
Articulated spacer provides long-term knee improvement after two-stage reimplantation
Authors
Michele Vasso
Chiara Del Regno
Katia Corona
Rocco D’Apolito
Alfredo Schiavone Panni
Publication date
01-10-2016
Publisher
Springer Berlin Heidelberg
Published in
Knee Surgery, Sports Traumatology, Arthroscopy / Issue 10/2016
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-016-4238-3

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