Top

Published in:

01-10-2020 | Hypoxemia | Editorial

Integrating the evidence: confronting the COVID-19 elephant

Authors: John J. Marini, R. Phillip Dellinger, Daniel Brodie

Published in: Intensive Care Medicine | Issue 10/2020

Excerpt

Coronavirus disease 2019 (COVID-19) is an unfamiliar illness with potentially devastating consequences. The pandemic is unfolding at different rates with wide geographic separation and seemingly erratic expression. There is well-justified urgency to describe the inconsistently expressed features of this new viral disease and implement strategies to avoid and treat it [1‐4]. …

Waterer GW, Rello J, Wunderink RG (2020) SARS-CoV-2: first do no harm. Am J Respir Crit Care Med. https://doi.org/10.1164/rccm.202004-1153EDCrossRefPubMedPubMedCentral

Morse JS, Lalonde T, Xu S et al (2020) Learning from the past: possible urgent prevention and treatment options for severe acute respiratory infections caused by 2019-nCoV. ChemBioChem 21(5):730–738. https://doi.org/10.1002/cbic.202000047CrossRefPubMedPubMedCentral

Wang Y, Zhang D, Du G et al (2020) Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial. Lancet 395:1569–1578CrossRefPubMedPubMedCentral

Chen L, Xiong J, Bao L et al (2020) Convalescent plasma as a potential therapy for COVID-19. Lancet Infect Dis 20(4):398–400CrossRefPubMedPubMedCentral

Johnson JT, Cain LM, Falk TL, Hayman J, Perillo E (1985) The, “Barnum effect” revisited: cognitive and motivational factors in the acceptance of personality descriptions. J Pers Soc Psychol 49:1378–1391CrossRef

Gattinoni L, Coppola S, Cressoni M, Busana M, Chiumello D (2020) Covid-19 does not lead to a “typical” acute respiratory distress syndrome. Am J Respir Crit Care Med 201(10):1299–1300. https://doi.org/10.1164/rccm.202003-0817LECrossRefPubMedPubMedCentral

Ashbaugh DG, Bigelow DB, Petty TL, Levine BE (1967) Acute respiratory distress in adults. Lancet 2(7511):319–323. https://doi.org/10.1016/s0140-6736(67)90168-7CrossRefPubMed

Farrell PM, Avery ME (1975) Hyaline membrane disease. Am Rev Respir Dis 111(5):657–688. https://doi.org/10.1164/arrd.1975.111.5.657CrossRefPubMed

Force ADT, Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E et al (2012) Acute respiratory distress syndrome: the Berlin Definition. JAMA 307(23):2526–2533

10.

Maiolo G, Collino F, Vasques F et al (2018) Reclassifying acute respiratory distress syndrome. Am J Respir Crit Care Med 197(12):1586–1595. https://doi.org/10.1164/rccm.201709-1804OCCrossRefPubMed

11.

Kallet RH, Branson RD (2007) Do the NIH ARDS Clinical Trials network PEEP/FiO₂ tables provide the best evidence-based guide to balancing PEEP and FiO₂ settings in adults? Respir Care 52(4):461–475PubMed

12.

Marini JJ, Rocco PRM, Gattinoni L (2020) Static and dynamic contributors to ventilator-induced lung injury in clinical practice. Pressure, energy, and power. Am J Respir Crit Care Med 201(7):767–774. https://doi.org/10.1164/rccm.201908-1545ciCrossRefPubMedPubMedCentral

13.

Marini JJ, Gattinoni L (2020) Management of Covid-19 respiratory distress. JAMA. https://doi.org/10.1001/jama.2020.6825CrossRefPubMed

14.

Mauri T, Spinelli E, Scotti E, Colussi G, Basile MC, Crotti S et al (2020) Potential for lung recruitment and ventilation-perfusion mismatch in patients with the acute respiratory distress syndrome from coronavirus disease 2019. Crit Care Med. https://doi.org/10.1097/CCM.0000000000004386CrossRefPubMedPubMedCentral

15.

Leisman DE, Deutschman CS, Legrand M (2020) Facing COVID-19 in the ICU: vascular dysfunction, thrombosis, and dysregulated inflammation. Intensive Care Med 46:1105–1108. https://doi.org/10.1007/s00134-020-06059-6CrossRefPubMedPubMedCentral

16.

London AJ, Kimmelman J (2020) Against pandemic research exceptionalism. Science 368(6490):476–477. https://doi.org/10.1126/science.abc1731CrossRefPubMed

17.

Bos LDJ, Sinha P, Dickson RP (2020) The perils of premature phenotyping in COVID: a call for caution. Eur Respir J 56:2001768. https://doi.org/10.1183/13993003.01768-2020CrossRefPubMedPubMedCentral

18.

Gattinoni L, Chiumello D, Caironi P, Busana M, Romitti F, Brazzi L, Camporota L (2020) COVID-19 pneumonia: different respiratory treatments for different phenotypes? Intensive Care Med. https://doi.org/10.1007/s00134-020-06033-2CrossRefPubMedPubMedCentral

Title: Integrating the evidence: confronting the COVID-19 elephant
Authors: John J. Marini
R. Phillip Dellinger
Daniel Brodie
Publication date: 01-10-2020
Publisher: Springer Berlin Heidelberg
Keywords: Hypoxemia
Acute Respiratory Distress-Syndrome
COVID-19
Published in: Intensive Care Medicine / Issue 10/2020
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-020-06195-z

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Integrating the evidence: confronting the COVID-19 elephant

Excerpt

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 10/2020

Severe malaria: a micro vessel disease

Phantom of the cannula …

Red cell alloimmunisation in patients receiving veno-venous extracorporeal membrane oxygenation (VV-ECMO)

Severity of endothelial dysfunction is associated with the occurrence of hemorrhagic complications in COPD patients treated by extracorporeal CO2 removal

Lung ultrasonography as an alternative to chest computed tomography in COVID-19 pneumonia?

Pulmonary immune responses against SARS-CoV-2 infection: harmful or not?