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01-04-2018 | Conference Reports and Expert Panel

Fluid therapy in neurointensive care patients: ESICM consensus and clinical practice recommendations

Authors: Mauro Oddo, Daniele Poole, Raimund Helbok, Geert Meyfroidt, Nino Stocchetti, Pierre Bouzat, Maurizio Cecconi, Thomas Geeraerts, Ignacio Martin-Loeches, Hervé Quintard, Fabio Silvio Taccone, Romergryko G. Geocadin, Claude Hemphill, Carole Ichai, David Menon, Jean-François Payen, Anders Perner, Martin Smith, José Suarez, Walter Videtta, Elisa R. Zanier, Giuseppe Citerio

Published in: Intensive Care Medicine | Issue 4/2018

Abstract

Objective

To report the ESICM consensus and clinical practice recommendations on fluid therapy in neurointensive care patients.

Design

A consensus committee comprising 22 international experts met in October 2016 during ESICM LIVES2016. Teleconferences and electronic-based discussions between the members of the committee subsequently served to discuss and develop the consensus process.

Methods

Population, intervention, comparison, and outcomes (PICO) questions were reviewed and updated as needed, and evidence profiles generated. The consensus focused on three main topics: (1) general fluid resuscitation and maintenance in neurointensive care patients, (2) hyperosmolar fluids for intracranial pressure control, (3) fluid management in delayed cerebral ischemia after subarachnoid haemorrhage. After an extensive literature search, the principles of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system were applied to assess the quality of evidence (from high to very low), to formulate treatment recommendations as strong or weak, and to issue best practice statements when applicable. A modified Delphi process based on the integration of evidence provided by the literature and expert opinions—using a sequential approach to avoid biases and misinterpretations—was used to generate the final consensus statement.

Results

The final consensus comprises a total of 32 statements, including 13 strong recommendations and 17 weak recommendations. No recommendations were provided for two statements.

Conclusions

We present a consensus statement and clinical practice recommendations on fluid therapy for neurointensive care patients.

Available only for authorised users

Andrews JC, Schunemann HJ, Oxman AD, Pottie K, Meerpohl JJ, Coello PA, Rind D, Montori VM, Brito JP, Norris S et al (2013) GRADE guidelines: 15. Going from evidence to recommendation-determinants of a recommendation’s direction and strength. J Clin Epidemiol 66(7):726–735CrossRefPubMed

Rabinstein AA, Bruder N (2011) Management of hyponatremia and volume contraction. Neurocrit Care 15(2):354–360CrossRefPubMed

Tisdall M, Crocker M, Watkiss J, Smith M (2006) Disturbances of sodium in critically ill adult neurologic patients: a clinical review. J Neurosurg Anesthesiol 18(1):57–63CrossRefPubMedPubMedCentral

Ginsberg MD, Palesch YY, Hill MD, Martin RH, Moy CS, Barsan WG, Waldman BD, Tamariz D, Ryckborst KJ, Alias et al (2013) High-dose albumin treatment for acute ischaemic stroke (ALIAS) Part 2: a randomised, double-blind, phase 3, placebo-controlled trial. Lancet Neurol 12(11):1049–1058CrossRefPubMedPubMedCentral

Palesch YY, Hill MD, Ryckborst KJ, Tamariz D, Ginsberg MD (2006) The ALIAS Pilot Trial: a dose-escalation and safety study of albumin therapy for acute ischemic stroke–II: neurologic outcome and efficacy analysis. Stroke 37(8):2107–2114CrossRefPubMed

SAFE Study Investigators, Australian and New Zealand Intensive Care Society Clinical Trials Group, Australian Red Cross Blood Service, George Institute for International Health, Myburgh J, Cooper DJ, Finfer S, Bellomo R, Norton R et al (2007) Saline or albumin for fluid resuscitation in patients with traumatic brain injury. N Engl J Med 357(9):874–884CrossRef

Kuwabara K, Fushimi K, Matsuda S, Ishikawa KB, Horiguchi H, Fujimori K (2013) Association of early post-procedure hemodynamic management with the outcomes of subarachnoid hemorrhage patients. J Neurol 260(3):820–831CrossRefPubMed

Suarez JI, Shannon L, Zaidat OO, Suri MF, Singh G, Lynch G, Selman WR (2004) Effect of human albumin administration on clinical outcome and hospital cost in patients with subarachnoid hemorrhage. J Neurosurg 100(4):585–590CrossRefPubMed

Ibrahim GM, Macdonald RL (2013) The effects of fluid balance and colloid administration on outcomes in patients with aneurysmal subarachnoid hemorrhage: a propensity score-matched analysis. Neurocrit Care 19(2):140–149CrossRefPubMed

10.

Tseng MY, Hutchinson PJ, Kirkpatrick PJ (2008) Effects of fluid therapy following aneurysmal subarachnoid haemorrhage: a prospective clinical study. Br J Neurosurg 22(2):257–268CrossRefPubMed

11.

Sekhon MS, Dhingra VK, Sekhon IS, Henderson WR, McLean N, Griesdale DE (2011) The safety of synthetic colloid in critically ill patients with severe traumatic brain injuries. J Crit Care 26(4):357–362CrossRefPubMed

12.

Lehmann L, Bendel S, Uehlinger DE, Takala J, Schafer M, Reinert M, Jakob SM (2013) Randomized, double-blind trial of the effect of fluid composition on electrolyte, acid-base, and fluid homeostasis in patients early after subarachnoid hemorrhage. Neurocrit Care 18(1):5–12CrossRefPubMed

13.

Roquilly A, Loutrel O, Cinotti R, Rosenczweig E, Flet L, Mahe PJ, Dumont R, Marie Chupin A, Peneau C, Lejus C et al (2013) Balanced versus chloride-rich solutions for fluid resuscitation in brain-injured patients: a randomised double-blind pilot study. Crit Care 17(2):R77CrossRefPubMedPubMedCentral

14.

Ioannidis JP (2008) Why most discovered true associations are inflated. Epidemiology 19(5):640–648CrossRefPubMed

15.

Shackford SR, Bourguignon PR, Wald SL, Rogers FB, Osler TM, Clark DE (1998) Hypertonic saline resuscitation of patients with head injury: a prospective, randomized clinical trial. J Trauma 44(1):50–58CrossRefPubMed

16.

Cooper DJ, Myles PS, McDermott FT, Murray LJ, Laidlaw J, Cooper G, Tremayne AB, Bernard SS, Ponsford J, HTS Study Investigators (2004) Prehospital hypertonic saline resuscitation of patients with hypotension and severe traumatic brain injury: a randomized controlled trial. JAMA 291(11):1350–1357CrossRefPubMed

17.

Baker AJ, Rhind SG, Morrison LJ, Black S, Crnko NT, Shek PN, Rizoli SB (2009) Resuscitation with hypertonic saline-dextran reduces serum biomarker levels and correlates with outcome in severe traumatic brain injury patients. J Neurotrauma 26(8):1227–1240CrossRefPubMed

18.

Ichai C, Payen JF, Orban JC, Quintard H, Roth H, Legrand R, Francony G, Leverve XM (2013) Half-molar sodium lactate infusion to prevent intracranial hypertensive episodes in severe traumatic brain injured patients: a randomized controlled trial. Intensive Care Med 39(8):1413–1422CrossRefPubMed

19.

Bentsen G, Breivik H, Lundar T, Stubhaug A (2006) Hypertonic saline (7.2%) in 6% hydroxyethyl starch reduces intracranial pressure and improves hemodynamics in a placebo-controlled study involving stable patients with subarachnoid hemorrhage. Crit Care Med 34(12):2912–2917CrossRefPubMed

20.

Cottenceau V, Masson F, Mahamid E, Petit L, Shik V, Sztark F, Zaaroor M, Soustiel JF (2011) Comparison of effects of equiosmolar doses of mannitol and hypertonic saline on cerebral blood flow and metabolism in traumatic brain injury. J Neurotrauma 28(10):2003–2012CrossRefPubMed

21.

Diringer MN, Scalfani MT, Zazulia AR, Videen TO, Dhar R, Powers WJ (2012) Effect of mannitol on cerebral blood volume in patients with head injury. Neurosurgery 70(5):1215–1218 (discussion 1219)CrossRefPubMedPubMedCentral

22.

Eskandari R, Filtz MR, Davis GE, Hoesch RE (2013) Effective treatment of refractory intracranial hypertension after traumatic brain injury with repeated boluses of 14.6% hypertonic saline. J Neurosurg 119(2):338–346CrossRefPubMed

23.

Francony G, Fauvage B, Falcon D, Canet C, Dilou H, Lavagne P, Jacquot C, Payen JF (2008) Equimolar doses of mannitol and hypertonic saline in the treatment of increased intracranial pressure. Crit Care Med 36(3):795–800CrossRefPubMed

24.

Hartl R, Ghajar J, Hochleuthner H, Mauritz W (1997) Hypertonic/hyperoncotic saline reliably reduces ICP in severely head-injured patients with intracranial hypertension. Acta Neurochir Suppl 70:126–129PubMed

25.

Helbok R, Kurtz P, Schmidt JM, Stuart RM, Fernandez L, Malhotra R, Presciutti M, Ostapkovich ND, Connolly ES, Lee K et al (2011) Effect of mannitol on brain metabolism and tissue oxygenation in severe haemorrhagic stroke. J Neurol Neurosurg Psychiatry 82(4):378–383CrossRefPubMed

26.

Huang SJ, Chang L, Han YY, Lee YC, Tu YK (2006) Efficacy and safety of hypertonic saline solutions in the treatment of severe head injury. Surg Neurol 65(6):539–546 (discussion 546)CrossRefPubMed

27.

Kerwin AJ, Schinco MA, Tepas JJ 3rd, Renfro WH, Vitarbo EA, Muehlberger M (2009) The use of 23.4% hypertonic saline for the management of elevated intracranial pressure in patients with severe traumatic brain injury: a pilot study. J Trauma 67(2):277–282CrossRefPubMed

28.

Launey Y, Nesseler N, Le Maguet P, Malledant Y, Seguin P (2014) Effect of osmotherapy on optic nerve sheath diameter in patients with increased intracranial pressure. J Neurotrauma 31(10):984–988CrossRefPubMed

29.

Lescot T, Degos V, Zouaoui A, Preteux F, Coriat P, Puybasset L (2006) Opposed effects of hypertonic saline on contusions and noncontused brain tissue in patients with severe traumatic brain injury. Crit Care Med 34(12):3029–3033CrossRefPubMed

30.

Major EH, O’Connor P, Mullan B (2015) Single bolus 30% hypertonic saline for refractory intracranial hypertension. Ir J Med Sci 184(1):159–165CrossRefPubMed

31.

Marshall LF, Smith RW, Rauscher LA, Shapiro HM (1978) Mannitol dose requirements in brain-injured patients. J Neurosurg 48(2):169–172CrossRefPubMed

32.

Mendelow AD, Teasdale GM, Russell T, Flood J, Patterson J, Murray GD (1985) Effect of mannitol on cerebral blood flow and cerebral perfusion pressure in human head injury. J Neurosurg 63(1):43–48CrossRefPubMed

33.

Miller JD, Piper IR, Dearden NM (1993) Management of intracranial hypertension in head injury: matching treatment with cause. Acta Neurochir Suppl (Wien) 57:152–159

34.

Muizelaar JP, Lutz HA 3rd, Becker DP (1984) Effect of mannitol on ICP and CBF and correlation with pressure autoregulation in severely head-injured patients. J Neurosurg 61(4):700–706CrossRefPubMed

35.

Oddo M, Levine JM, Frangos S, Carrera E, Maloney-Wilensky E, Pascual JL, Kofke WA, Mayer SA, LeRoux PD (2009) Effect of mannitol and hypertonic saline on cerebral oxygenation in patients with severe traumatic brain injury and refractory intracranial hypertension. J Neurol Neurosurg Psychiatry 80(8):916–920CrossRefPubMed

36.

Rockswold GL, Solid CA, Paredes-Andrade E, Rockswold SB, Jancik JT, Quickel RR (2009) Hypertonic saline and its effect on intracranial pressure, cerebral perfusion pressure, and brain tissue oxygen. Neurosurgery 65(6):1035–1041 (discussion 1041–1032)CrossRefPubMed

37.

Roquilly A, Mahe PJ, Latte DD, Loutrel O, Champin P, Di Falco C, Courbe A, Buffenoir K, Hamel O, Lejus C et al (2011) Continuous controlled-infusion of hypertonic saline solution in traumatic brain-injured patients: a 9-year retrospective study. Crit Care 15(5):R260CrossRefPubMedPubMedCentral

38.

Rosner MJ, Coley I (1987) Cerebral perfusion pressure: a hemodynamic mechanism of mannitol and the postmannitol hemogram. Neurosurgery 21(2):147–156CrossRefPubMed

39.

Sakowitz OW, Stover JF, Sarrafzadeh AS, Unterberg AW, Kiening KL (2007) Effects of mannitol bolus administration on intracranial pressure, cerebral extracellular metabolites, and tissue oxygenation in severely head-injured patients. J Trauma 62(2):292–298CrossRefPubMed

40.

Scalfani MT, Dhar R, Zazulia AR, Videen TO, Diringer MN (2012) Effect of osmotic agents on regional cerebral blood flow in traumatic brain injury. J Crit Care 27(5):526 (e527–e512)CrossRefPubMed

41.

Schwarz S, Georgiadis D, Aschoff A, Schwab S (2002) Effects of hypertonic (10%) saline in patients with raised intracranial pressure after stroke. Stroke 33(1):136–140CrossRefPubMed

42.

Schwarz S, Schwab S, Bertram M, Aschoff A, Hacke W (1998) Effects of hypertonic saline hydroxyethyl starch solution and mannitol in patients with increased intracranial pressure after stroke. Stroke 29(8):1550–1555CrossRefPubMed

43.

Soustiel JF, Mahamid E, Chistyakov A, Shik V, Benenson R, Zaaroor M (2006) Comparison of moderate hyperventilation and mannitol for control of intracranial pressure control in patients with severe traumatic brain injury—a study of cerebral blood flow and metabolism. Acta Neurochir (Wien) 148(8):845–851 (discussion 851)CrossRef

44.

Tseng MY, Al-Rawi PG, Czosnyka M, Hutchinson PJ, Richards H, Pickard JD, Kirkpatrick PJ (2007) Enhancement of cerebral blood flow using systemic hypertonic saline therapy improves outcome in patients with poor-grade spontaneous subarachnoid hemorrhage. J Neurosurg 107(2):274–282CrossRefPubMed

45.

Ware ML, Nemani VM, Meeker M, Lee C, Morabito DJ, Manley GT (2005) Effects of 23.4% sodium chloride solution in reducing intracranial pressure in patients with traumatic brain injury: a preliminary study. Neurosurgery 57(4):727–736 (discussion 727–736)CrossRefPubMed

46.

Higgins JP, Thompson SG (2004) Controlling the risk of spurious findings from meta-regression. Stat Med 23(11):1663–1682CrossRefPubMed

47.

Ichai C, Armando G, Orban JC, Berthier F, Rami L, Samat-Long C, Grimaud D, Leverve X (2009) Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients. Intensive Care Med 35(3):471–479CrossRefPubMed

48.

Jagannatha AT, Sriganesh K, Devi BI, Rao GS (2016) An equiosmolar study on early intracranial physiology and long term outcome in severe traumatic brain injury comparing mannitol and hypertonic saline. J Clin Neurosci 27:68–73CrossRefPubMed

49.

Sakellaridis N, Pavlou E, Karatzas S, Chroni D, Vlachos K, Chatzopoulos K, Dimopoulou E, Kelesis C, Karaouli V (2011) Comparison of mannitol and hypertonic saline in the treatment of severe brain injuries. J Neurosurg 114(2):545–548CrossRefPubMed

50.

Vialet R, Albanese J, Thomachot L, Antonini F, Bourgouin A, Alliez B, Martin C (2003) Isovolume hypertonic solutes (sodium chloride or mannitol) in the treatment of refractory posttraumatic intracranial hypertension: 2 mL/kg 7.5% saline is more effective than 2 mL/kg 20% mannitol. Crit Care Med 31(6):1683–1687CrossRefPubMed

51.

Battison C, Andrews PJ, Graham C, Petty T (2005) Randomized, controlled trial on the effect of a 20% mannitol solution and a 7.5% saline/6% dextran solution on increased intracranial pressure after brain injury. Crit Care Med 33(1):196–202 (discussion 257–198)CrossRefPubMed

52.

Harutjunyan L, Holz C, Rieger A, Menzel M, Grond S, Soukup J (2005) Efficiency of 7.2% hypertonic saline hydroxyethyl starch 200/0.5 versus mannitol 15% in the treatment of increased intracranial pressure in neurosurgical patients—a randomized clinical trial [ISRCTN62699180]. Crit Care 9(5):R530–R540CrossRefPubMedPubMedCentral

53.

Mangat HS, Chiu YL, Gerber LM, Alimi M, Ghajar J, Hartl R (2015) Hypertonic saline reduces cumulative and daily intracranial pressure burdens after severe traumatic brain injury. J Neurosurg 122(1):202–210CrossRefPubMed

54.

Misra UK, Kalita J, Vajpayee A, Phadke RV, Hadique A, Savlani V (2007) Effect of single mannitol bolus in intracerebral hemorrhage. Eur J Neurol 14(10):1118–1123CrossRefPubMed

55.

Diringer MN, Scalfani MT, Zazulia AR, Videen TO, Dhar R (2011) Cerebral hemodynamic and metabolic effects of equi-osmolar doses mannitol and 23.4% saline in patients with edema following large ischemic stroke. Neurocrit Care 14(1):11–17CrossRefPubMedPubMedCentral

56.

Ye H, Su Y (2013) Hemodynamic effects of mannitol infusion in patients with acute intracerebral hemorrhage. Acta Cir Bras 28(2):106–111CrossRefPubMed

57.

Al-Rawi PG, Tseng MY, Richards HK, Nortje J, Timofeev I, Matta BF, Hutchinson PJ, Kirkpatrick PJ (2010) Hypertonic saline in patients with poor-grade subarachnoid hemorrhage improves cerebral blood flow, brain tissue oxygen, and pH. Stroke 41(1):122–128CrossRefPubMed

58.

Jafar JJ, Johns LM, Mullan SF (1986) The effect of mannitol on cerebral blood flow. J Neurosurg 64(5):754–759CrossRefPubMed

59.

Manno EM, Adams RE, Derdeyn CP, Powers WJ, Diringer MN (1999) The effects of mannitol on cerebral edema after large hemispheric cerebral infarct. Neurology 52(3):583–587CrossRefPubMed

60.

Nath F, Galbraith S (1986) The effect of mannitol on cerebral white matter water content. J Neurosurg 65(1):41–43CrossRefPubMed

61.

Qureshi AI, Suarez JI, Bhardwaj A, Mirski M, Schnitzer MS, Hanley DF, Ulatowski JA (1998) Use of hypertonic (3%) saline/acetate infusion in the treatment of cerebral edema: effect on intracranial pressure and lateral displacement of the brain. Crit Care Med 26(3):440–446CrossRefPubMed

62.

Videen TO, Zazulia AR, Manno EM, Derdeyn CP, Adams RE, Diringer MN, Powers WJ (2001) Mannitol bolus preferentially shrinks non-infarcted brain in patients with ischemic stroke. Neurology 57(11):2120–2122CrossRefPubMed

63.

Huang Z, Dong W, Yan Y, Xiao Q, Man Y (2002) Effects of intravenous mannitol on EEG recordings in stroke patients. Clin Neurophysiol 113(3):446–453CrossRefPubMed

64.

Wang X, Arima H, Yang J, Zhang S, Wu G, Woodward M, Munoz-Venturelli P, Lavados PM, Stapf C, Robinson T et al (2015) Mannitol and outcome in intracerebral hemorrhage: propensity score and multivariable intensive blood pressure reduction in acute cerebral hemorrhage trial 2 results. Stroke 46(10):2762–2767CrossRefPubMed

65.

Bereczki D, Mihalka L, Szatmari S, Fekete K, Di Cesar D, Fulesdi B, Csiba L, Fekete I (2003) Mannitol use in acute stroke: case fatality at 30 days and 1 year. Stroke 34(7):1730–1735CrossRefPubMed

66.

Wade CE, Grady JJ, Kramer GC, Younes RN, Gehlsen K, Holcroft JW (1997) Individual patient cohort analysis of the efficacy of hypertonic saline/dextran in patients with traumatic brain injury and hypotension. J Trauma 42(5 Suppl):S61–S65CrossRefPubMed

67.

Asehnoune K, Lasocki S, Seguin P, Geeraerts T, Perrigault PF, Dahyot-Fizelier C, Paugam Burtz C, Cook F, Demeure Dit Latte D, Cinotti R et al (2017) Association between continuous hyperosmolar therapy and survival in patients with traumatic brain injury—a multicentre prospective cohort study and systematic review. Crit Care 21(1):328CrossRefPubMedPubMedCentral

68.

Egge A, Waterloo K, Sjoholm H, Solberg T, Ingebrigtsen T, Romner B (2001) Prophylactic hyperdynamic postoperative fluid therapy after aneurysmal subarachnoid hemorrhage: a clinical, prospective, randomized, controlled study. Neurosurgery 49(3):593–605 (discussion 605–596)PubMed

69.

Lennihan L, Mayer SA, Fink ME, Beckford A, Paik MC, Zhang H, Wu YC, Klebanoff LM, Raps EC, Solomon RA (2000) Effect of hypervolemic therapy on cerebral blood flow after subarachnoid hemorrhage: a randomized controlled trial. Stroke 31(2):383–391CrossRefPubMed

70.

Martini RP, Deem S, Brown M, Souter MJ, Yanez ND, Daniel S, Treggiari MM (2012) The association between fluid balance and outcomes after subarachnoid hemorrhage. Neurocrit Care 17(2):191–198CrossRefPubMed

71.

Tagami T, Kuwamoto K, Watanabe A, Unemoto K, Yokobori S, Matsumoto G, Igarashi Y, Yokota H (2014) Group SAHPS: effect of triple-h prophylaxis on global end-diastolic volume and clinical outcomes in patients with aneurysmal subarachnoid hemorrhage. Neurocrit Care 21(3):462–469CrossRefPubMed

72.

Kissoon NR, Mandrekar JN, Fugate JE, Lanzino G, Wijdicks EF, Rabinstein AA (2015) Positive fluid balance is associated with poor outcomes in subarachnoid hemorrhage. J Stroke Cerebrovasc Dis 24(10):2245–2251CrossRefPubMed

73.

Muench E, Horn P, Bauhuf C, Roth H, Philipps M, Hermann P, Quintel M, Schmiedek P, Vajkoczy P (2007) Effects of hypervolemia and hypertension on regional cerebral blood flow, intracranial pressure, and brain tissue oxygenation after subarachnoid hemorrhage. Crit Care Med 35(8):1844–1851 (quiz 1852)CrossRefPubMed

74.

Al-Rawi PG, Zygun D, Tseng MY, Hutchinson PJ, Matta BF, Kirkpatrick PJ (2005) Cerebral blood flow augmentation in patients with severe subarachnoid haemorrhage. Acta Neurochir Suppl 95:123–127CrossRefPubMed

75.

Tseng MY, Al-Rawi PG, Pickard JD, Rasulo FA, Kirkpatrick PJ (2003) Effect of hypertonic saline on cerebral blood flow in poor-grade patients with subarachnoid hemorrhage. Stroke 34(6):1389–1396CrossRefPubMed

76.

Yamakami I, Isobe K, Yamaura A (1987) Effects of intravascular volume expansion on cerebral blood flow in patients with ruptured cerebral aneurysms. Neurosurgery 21(3):303–309CrossRefPubMed

77.

Dhar R, Scalfani MT, Zazulia AR, Videen TO, Derdeyn CP, Diringer MN (2012) Comparison of induced hypertension, fluid bolus, and blood transfusion to augment cerebral oxygen delivery after subarachnoid hemorrhage. J Neurosurg 116(3):648–656CrossRefPubMed

78.

Italian Acute Stroke Study Group (1988) Haemodilution in acute stroke: results of the Italian haemodilution trial. Lancet 1(8581):318–321

79.

Dharmasaroja PA (2016) Fluid intake related to brain edema in acute middle cerebral artery infarction. Transl Stroke Res 7(1):49–53CrossRefPubMed

80.

Jost SC, Diringer MN, Zazulia AR, Videen TO, Aiyagari V, Grubb RL, Powers WJ (2005) Effect of normal saline bolus on cerebral blood flow in regions with low baseline flow in patients with vasospasm following subarachnoid hemorrhage. J Neurosurg 103(1):25–30CrossRefPubMed

81.

Mori K, Arai H, Nakajima K, Tajima A, Maeda M (1995) Hemorheological and hemodynamic analysis of hypervolemic hemodilution therapy for cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Stroke 26(9):1620–1626CrossRefPubMed

82.

Kim CY, Paek SH, Seo BG, Kim JH, Han DH (2003) Changes in vascular responses of the basilar artery to acetylcholine and endothelin-1 in an experimental rabbit vasospasm model. Acta Neurochir (Wien) 145(7):571–577CrossRef

83.

Ekelund A, Reinstrup P, Ryding E, Andersson AM, Molund T, Kristiansson KA, Romner B, Brandt L, Saveland H (2002) Effects of iso- and hypervolemic hemodilution on regional cerebral blood flow and oxygen delivery for patients with vasospasm after aneurysmal subarachnoid hemorrhage. Acta Neurochir (Wien) 144(7):703–712 (discussion 712–703)CrossRef

84.

Shimoda M, Oda S, Tsugane R, Sato O (1993) Intracranial complications of hypervolemic therapy in patients with a delayed ischemic deficit attributed to vasospasm. J Neurosurg 78(3):423–429CrossRefPubMed

85.

Tanabe T, Saitoh T, Tachibana S, Takagi H, Yada K (1982) Effect of hyperdynamic therapy on cerebral ischaemia caused by vasospasm associated with subarachnoid haemorrhage. Acta Neurochir (Wien) 63(1–4):291–296CrossRef

86.

Kurtz P, Helbok R, Ko SB, Claassen J, Schmidt JM, Fernandez L, Stuart RM, Connolly ES, Badjatia N, Mayer SA et al (2014) Fluid responsiveness and brain tissue oxygen augmentation after subarachnoid hemorrhage. Neurocrit Care 20(2):247–254CrossRefPubMed

87.

Mutoh T, Kazumata K, Terasaka S, Taki Y, Suzuki A, Ishikawa T (2014) Early intensive versus minimally invasive approach to postoperative hemodynamic management after subarachnoid hemorrhage. Stroke 45(5):1280–1284CrossRefPubMed

88.

Mutoh T, Kazumata K, Terasaka S, Taki Y, Suzuki A, Ishikawa T (2014) Impact of transpulmonary thermodilution-based cardiac contractility and extravascular lung water measurements on clinical outcome of patients with Takotsubo cardiomyopathy after subarachnoid hemorrhage: a retrospective observational study. Crit Care 18(4):482CrossRefPubMedPubMedCentral

89.

Tagami T, Kuwamoto K, Watanabe A, Unemoto K, Yokobori S, Matsumoto G, Yokota H (2014) Group SAHPS: optimal range of global end-diastolic volume for fluid management after aneurysmal subarachnoid hemorrhage: a multicenter prospective cohort study. Crit Care Med 42(6):1348–1356CrossRefPubMed

90.

Yoneda H, Nakamura T, Shirao S, Tanaka N, Ishihara H, Suehiro E, Koizumi H, Isotani E, Suzuki M (2013) Group SAHPS: multicenter prospective cohort study on volume management after subarachnoid hemorrhage: hemodynamic changes according to severity of subarachnoid hemorrhage and cerebral vasospasm. Stroke 44(8):2155–2161CrossRefPubMed

Title: Fluid therapy in neurointensive care patients: ESICM consensus and clinical practice recommendations
Authors: Mauro Oddo
Daniele Poole
Raimund Helbok
Geert Meyfroidt
Nino Stocchetti
Pierre Bouzat
Maurizio Cecconi
Thomas Geeraerts
Ignacio Martin-Loeches
Hervé Quintard
Fabio Silvio Taccone
Romergryko G. Geocadin
Claude Hemphill
Carole Ichai
David Menon
Jean-François Payen
Anders Perner
Martin Smith
José Suarez
Walter Videtta
Elisa R. Zanier
Giuseppe Citerio
Publication date: 01-04-2018
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 4/2018
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-018-5086-z

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Fluid therapy in neurointensive care patients: ESICM consensus and clinical practice recommendations

Abstract

Objective

Design

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Objective

Design

Methods

Results

Conclusions

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