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01-08-2018 | Understanding the Disease

Understanding the role of host immune responses in invasive candidiasis

Authors: Jigar V. Desai, Frank L. van de Veerdonk, Michail S. Lionakis

Published in: Intensive Care Medicine | Issue 8/2018

Excerpt

Invasive candidiasis is the most common nosocomial bloodstream mycosis in the ICU affecting > 250,000 individuals annually worldwide [1]. It is most often caused by Candida albicans, a commensal yeast of mucosal surfaces, although infections by non-albicans species, including C. glabrata, C. tropicalis and C. parapsilosis are increasing [1]. The recent global emergence of C. auris raises public health concerns because of the species’ multidrug-resistance and resilience to antiseptics, its misidentification by routine microbiological techniques, and its persistence on human skin and hospital environment that causes hospital-associated horizontal transmission and outbreaks [2]. …

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Title: Understanding the role of host immune responses in invasive candidiasis
Authors: Jigar V. Desai
Frank L. van de Veerdonk
Michail S. Lionakis
Publication date: 01-08-2018
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 8/2018
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-017-4988-5

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