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01-09-2017 | Research Agenda

The intensive care medicine research agenda on septic shock

Authors: Anders Perner, Anthony C. Gordon, Derek C. Angus, Francois Lamontagne, Flavia Machado, James A. Russell, Jean-Francois Timsit, John C. Marshall, John Myburgh, Manu Shankar-Hari, Mervyn Singer

Published in: Intensive Care Medicine | Issue 9/2017

Abstract

Septic shock remains a global health challenge with millions of cases every year, high rates of mortality and morbidity, impaired quality of life among survivors and relatives, and high resource use both in developed and developing nations. Care and outcomes are improving through organisational initiatives and updated clinical practice guidelines based on clinical research mainly carried out by large collaborative networks. This progress is likely to continue through the collaborative work of the established and merging trials groups in many parts of the world and through refined trial methodology and translational work. In this review, international experts summarize the current position of clinical research in septic shock and propose a research agenda to advance this field.

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Title: The intensive care medicine research agenda on septic shock
Authors: Anders Perner
Anthony C. Gordon
Derek C. Angus
Francois Lamontagne
Flavia Machado
James A. Russell
Jean-Francois Timsit
John C. Marshall
John Myburgh
Manu Shankar-Hari
Mervyn Singer
Publication date: 01-09-2017
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 9/2017
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-017-4821-1

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