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01-11-2017 | Editorial

Fixed minimum fluid volume for resuscitation: Con

Authors: Anders Perner, Mervyn Singer

Published in: Intensive Care Medicine | Issue 11/2017

Excerpt

The Surviving Sepsis Campaign guideline recommends a minimum IV fluid volume of 30 ml/kg body weight during initial fluid resuscitation for patients with septic shock [1]. This document acknowledges the limited evidence supporting this recommendation. No randomised trial has specifically assessed different fluid volumes for initial resuscitation in adults with septic shock. We believe that this recommendation may be challenged for the reasons given below. …

Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb S, Beale RJ, Vincent JL, Moreno R (2013) Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med 39:165–228CrossRefPubMed

Bloch A, Berger D, Takala J (2016) Understanding circulatory failure in sepsis. Intensive Care Med. doi:10.1007/s00134-016-4514-1

Berlin DA, Bakker J (2014) Understanding venous return. Intensive Care Med 40:1564–1566CrossRefPubMed

Angus DC, Barnato AE, Bell D, Bellomo R, Chong CR, Coats TJ, Davies A, Delaney A, Harrison DA, Holdgate A, Howe B, Huang DT, Iwashyna T, Kellum JA, Peake SL, Pike F, Reade MC, Rowan KM, Singer M, Webb SA, Weissfeld LA, Yealy DM, Young JD (2015) A systematic review and meta-analysis of early goal-directed therapy for septic shock: the ARISE, ProCESS and ProMISe Investigators. Intensive Care Med 41:1549–1560CrossRefPubMed

Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent JL, Angus DC (2016) The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA 315:801–810CrossRefPubMedPubMedCentral

Maitland K, Kiguli S, Opoka RO, Engoru C, Olupot-Olupot P, Akech SO, Nyeko R, Mtove G, Reyburn H, Lang T, Brent B, Evans JA, Tibenderana JK, Crawley J, Russell EC, Levin M, Babiker AG, Gibb DM (2011) Mortality after fluid bolus in African children with severe infection. New Engl J Med 364:2483–2495CrossRefPubMed

Maitland K, George EC, Evans JA, Kiguli S, Olupot-Olupot P, Akech SO, Opoka RO, Engoru C, Nyeko R, Mtove G, Reyburn H, Brent B, Nteziyaremye J, Mpoya A, Prevatt N, Dambisya CM, Semakula D, Ddungu A, Okuuny V, Wokulira R, Timbwa M, Otii B, Levin M, Crawley J, Babiker AG, Gibb DM (2013) Exploring mechanisms of excess mortality with early fluid resuscitation: insights from the FEAST trial. BMC Med 11:68CrossRefPubMedPubMedCentral

Boyd JH, Forbes J, Nakada TA, Walley KR, Russell JA (2011) Fluid resuscitation in septic shock: a positive fluid balance and elevated central venous pressure are associated with increased mortality. Crit Care Med 39:259–265CrossRefPubMed

Acheampong A, Vincent JL (2015) A positive fluid balance is an independent prognostic factor in patients with sepsis. Crit Care 19:251CrossRefPubMedPubMedCentral

10.

Hjortrup PB, Haase N, Bundgaard H, Thomsen SL, Winding R, Pettila V, Aaen A, Lodahl D, Berthelsen RE, Christensen H, Madsen MB, Winkel P, Wetterslev J, Perner A, The CLASSIC Trial Group, The Scandinavian Critical Care Trials Group (2016) Restricting volumes of resuscitation fluid in adults with septic shock after initial management: the CLASSIC randomised, parallel-group, multicentre feasibility trial. Intensive Care Med. doi:10.1007/s00134-016-4500-7

11.

Silversides JA, Major E, Ferguson JF, Mann EM, McAuley DF, Marshall JC, Blackwood B, Fan E (2016) Conservative fluid management or deresuscitation for patients with sepsis or acute respiratory distress syndrome following the resuscitation phase of critical illness: a systematic review and meta-analysis. Intensive Care Med. doi:10.1007/s00134-016-4573-3

12.

Dunser MW, Ruokonen E, Pettila V, Ulmer H, Torgersen C, Schmittinger CA, Jakob S, Takala J (2009) Association of arterial blood pressure and vasopressor load with septic shock mortality: a post hoc analysis of a multicenter trial. Crit Care 13:R181CrossRefPubMedPubMedCentral

13.

Andreis DT, Singer M (2016) Catecholamines for inflammatory shock: a Jekyll-and-Hyde conundrum. Intensive Care Med 42:1387–1397CrossRefPubMed

Title: Fixed minimum fluid volume for resuscitation: Con
Authors: Anders Perner
Mervyn Singer
Publication date: 01-11-2017
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 11/2017
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-016-4581-3

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