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Published in: Intensive Care Medicine 10/2014

01-10-2014 | Understanding the Disease

Understanding venous return

Authors: David A. Berlin, Jan Bakker

Published in: Intensive Care Medicine | Issue 10/2014

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Excerpt

Cardiac output can increase fivefold to adapt to changing metabolic needs. Since normal contraction empties the heart of nearly all its blood, simply increasing the force or rate of contraction cannot explain the dramatic increase in cardiac output. Instead, the circulation mobilizes a large volume of blood from the compliant veins. The venous system stores two-thirds of the blood volume and serve as an adjustable reservoir [1, 2]. The Starling law explains that cardiac output is intrinsically coupled to the rate of blood return to the heart [1]. To increase cardiac output, the circulation increases venous return—the rate of blood flowing from the systemic veins into the right atrium. This review will discuss the mechanisms that regulate venous return. …
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Metadata
Title
Understanding venous return
Authors
David A. Berlin
Jan Bakker
Publication date
01-10-2014
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 10/2014
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-014-3379-4

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