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Published in: Intensive Care Medicine 5/2016

01-05-2016 | Review

Venovenous extracorporeal membrane oxygenation for acute respiratory failure

A clinical review from an international group of experts

Authors: Eddy Fan, Luciano Gattinoni, Alain Combes, Matthieu Schmidt, Giles Peek, Dan Brodie, Thomas Muller, Andrea Morelli, V. Marco Ranieri, Antonio Pesenti, Laurent Brochard, Carol Hodgson, Cecile Van Kiersbilck, Antoine Roch, Michael Quintel, Laurent Papazian

Published in: Intensive Care Medicine | Issue 5/2016

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Abstract

Despite expensive life-sustaining interventions delivered in the ICU, mortality and morbidity in patients with acute respiratory failure (ARF) remain unacceptably high. Extracorporeal membrane oxygenation (ECMO) has emerged as a promising intervention that may provide more efficacious supportive care to these patients. Improvements in technology have made ECMO safer and easier to use, allowing for the potential of more widespread application in patients with ARF. A greater appreciation of the complications associated with the placement of an artificial airway and mechanical ventilation has led clinicians and researchers to seek viable alternatives to providing supportive care in these patients. Thus, this review will summarize the current knowledge regarding the use of venovenous (VV)-ECMO for ARF and describe some of the recent controversies in the field, such as mechanical ventilation, anticoagulation and transfusion therapy, and ethical concerns in patients supported with VV-ECMO.
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Metadata
Title
Venovenous extracorporeal membrane oxygenation for acute respiratory failure
A clinical review from an international group of experts
Authors
Eddy Fan
Luciano Gattinoni
Alain Combes
Matthieu Schmidt
Giles Peek
Dan Brodie
Thomas Muller
Andrea Morelli
V. Marco Ranieri
Antonio Pesenti
Laurent Brochard
Carol Hodgson
Cecile Van Kiersbilck
Antoine Roch
Michael Quintel
Laurent Papazian
Publication date
01-05-2016
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 5/2016
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-016-4314-7

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