Open Access 01-12-2009 | Pediatric Brief Report
Effect of closed endotracheal suction in high-frequency ventilated premature infants measured with electrical impedance tomography
Published in: Intensive Care Medicine | Issue 12/2009
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Objective
To determine the global and regional changes in lung volume during and after closed endotracheal tube (ETT) suction in high-frequency ventilated preterm infants with respiratory distress syndrome (RDS).
Design
Prospective observational clinical study.
Setting
Neonatal intensive care unit.
Patients
Eleven non-muscle relaxed preterm infants with RDS ventilated with open lung high-frequency ventilation (HFV).
Interventions
Closed ETT suction.
Measurements and results
Changes in global and regional lung volume were measured with electrical impedance tomography. ETT suction resulted in an acute loss of lung volume followed by spontaneous recovery with a median residual loss of 3.3% of the maximum volume loss. The median stabilization time was 8 s. At the regional level, the lung volume changes during and after ETT suction were heterogeneous in nature.
Conclusions
Closed ETT suction causes an acute, transient and heterogeneous loss of lung volume in premature infants with RDS treated with open lung HFV.