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Intensive Care Medicine
Published in: Intensive Care Medicine 10/2007

01-10-2007 | Editorial

Invasive aspergillosis in the ICU: an emerging disease

Authors: Wouter Meersseman, Eric Van Wijngaerden

Published in: Intensive Care Medicine | Issue 10/2007

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Excerpt

In Intensive Care Medicine Trof and colleagues [1] now present a very useful review of invasive pulmonary aspergillosis (IPA) in the ICU. This is a very timely topic and an increasingly important one given the emerging data in the area. Aspergillus spp. are ubiquitous fungi acquired by inhalation of airborne spores. Humans inhale hundreds of conidia per day without adverse consequences, except for a small minority of persons in whom conidia escape phagocytosis by alveolar macrophages and germinate into hyphae. These hyphael elements can be destroyed by circulating neutrophils. If, however, defense systems fail, a life-threatening angioinvasive form of aspergillosis can develop. The bulk of literature about IPA involves patients with classical risk factors such as prolonged neutropenia and transplant recipients [2, 3]. …
Literature
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Trof RJ, Beishuizen A, Debets-Ossenkopp YJ, Girbes ARJ, Groeneveld ABJ (2007) Management of invasive pulmonary aspergillosis in non-neutropenic critically ill patients. Intensive Care Med (DOI 10.​1007/​s00134-007-0791-z)
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Metadata
Title
Invasive aspergillosis in the ICU: an emerging disease
Authors
Wouter Meersseman
Eric Van Wijngaerden
Publication date
01-10-2007
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 10/2007
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-007-0792-y

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