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Published in: Intensive Care Medicine 10/2007

01-10-2007 | Original

Continuous monitoring of ScvO2 by a new fibre-optic technology compared with blood gas oximetry in critically ill patients: a multicentre study

Authors: Zsolt Molnar, Andreas Umgelter, Ildiko Toth, David Livingstone, Andreas Weyland, Samir G. Sakka, Andreas Meier-Hellmann

Published in: Intensive Care Medicine | Issue 10/2007

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Abstract

Objective

The aim of this study was to compare the accuracy of the CeVOX monitor measuring continuous central venous saturation (ScvO2) with laboratory blood gas oximetry under clinical circumstances.

Design

Prospective, multicentre, observational study.

Setting

Five adult general intensive care units.

Patients and participants

Fifty-three critically ill patients.

Interventions

The fibre-optic probe was inserted into an ordinary central venous catheter's distal lumen. Blood samples were taken from this line via a Y-adapter every 8 h and ScvO2 was measured with a laboratory co-oximeter. Patients were observed for a maximum of 5 days. Results were compared using linear regression and the Bland and Altman plots.

Measurements and results

The 526 matched pairs of ScvO2 showed a significant correlation between the two methods (r = 0.79, p< 0.001). Bland–Altman plots showed an overall mean bias of –0.3% and moderate agreement (lower and upper levels of agreement: –13.2% and 12.5%). Correlation for the first time point, and for differences between the first two time points for each method revealed good correlation: (n = 53): r = 0.79, p< 0.001; (n = 50): r = 0.58, p< 0.001, respectively.

Conclusion

These results in a heterogeneous group of critically ill patients show that continuous ScvO2 monitoring by the CeVOX technology yielded results comparable with those obtained by laboratory co-oximetry and therefore can be relied on in everyday clinical practice.
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Metadata
Title
Continuous monitoring of ScvO2 by a new fibre-optic technology compared with blood gas oximetry in critically ill patients: a multicentre study
Authors
Zsolt Molnar
Andreas Umgelter
Ildiko Toth
David Livingstone
Andreas Weyland
Samir G. Sakka
Andreas Meier-Hellmann
Publication date
01-10-2007
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 10/2007
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-007-0743-7

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