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Published in: Intensive Care Medicine 8/2007

01-08-2007 | Pediatric Original

Pediatric Index of Mortality 2 score in Italy: a multicenter, prospective, observational study

Authors: Andrea Wolfler, Paolo Silvani, Massimo Musicco, Ida Salvo, Italian Pediatric Sepsis Study (SISPe) Group

Published in: Intensive Care Medicine | Issue 8/2007

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Abstract

Objectives

To assess the performance of the Pediatric Index of Mortality (PIM) 2 score in Italian pediatric intensive care units (PICUs).

Design

Prospective, observational, multicenter, 1-year study.

Setting

Eighteen medical–surgical PICUs.

Patients

Consecutive patients (3266) aged 0–16 years admitted between 1 March 2004 and 28 February 2005.

Interventions

None.

Measurements and main results

To assess the performance of the PIM2 score, discrimination and calibration measures were applied to all children admitted to the 18 PICUs, in the entire population and in different groups divided for deciles of risk, age and admission diagnosis. There was good discrimination, with an area under the receiver operating characteristic (ROC) curve of 0.89 (95% CI 0.86–0.91) and good calibration of the scoring system [non-significant differences between observed and predicted deaths when the population was stratified according to deciles of risk (χ2 9.86; 8 df, p = 0.26) for the whole population].

Conclusions

The PIM2 score performed well in this sample of the Italian pediatric intensive care population. It may need to be reassessed in the injury and postoperative groups in larger studies.
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Literature
1.
go back to reference Tilford JM, Roberson PK, Lensing S, Fiser DH (1998) Differences in pediatric ICU mortality risk over time. Crit Care Med 26:1737–1743PubMedCrossRef Tilford JM, Roberson PK, Lensing S, Fiser DH (1998) Differences in pediatric ICU mortality risk over time. Crit Care Med 26:1737–1743PubMedCrossRef
2.
go back to reference Pollack MM, Cuerdon TC, Getson PR (1993) Pediatric intensive care units: results of a national survey. Crit Care Med 21:607–613PubMedCrossRef Pollack MM, Cuerdon TC, Getson PR (1993) Pediatric intensive care units: results of a national survey. Crit Care Med 21:607–613PubMedCrossRef
3.
go back to reference Gemke RJBJ, Bonsel GJ (1995) Comparative assessment of pediatric intensive care: A national multicenter study. Crit Care Med 23:238–245PubMedCrossRef Gemke RJBJ, Bonsel GJ (1995) Comparative assessment of pediatric intensive care: A national multicenter study. Crit Care Med 23:238–245PubMedCrossRef
4.
go back to reference Slater A, Shann F, for the Anzics Paediatric Study Group (2004) The suitability of the Pediatric Index of Mortality (PIM), PIM2, the Pediatric Risk of Mortality (PRISM), and PRISM III for monitoring the quality of pediatric intensive care in Australia and New Zealand. Pediatr Crit Care Med 5:447–454PubMedCrossRef Slater A, Shann F, for the Anzics Paediatric Study Group (2004) The suitability of the Pediatric Index of Mortality (PIM), PIM2, the Pediatric Risk of Mortality (PRISM), and PRISM III for monitoring the quality of pediatric intensive care in Australia and New Zealand. Pediatr Crit Care Med 5:447–454PubMedCrossRef
5.
go back to reference Bertolini G, Ripamonti D, Cattaneo A, Apolone G (1998) Pediatric Risk of Mortality: an assessment of its performance in a sample of 26 Italian intensive care units. Crit Care Med 26:1427–1432PubMedCrossRef Bertolini G, Ripamonti D, Cattaneo A, Apolone G (1998) Pediatric Risk of Mortality: an assessment of its performance in a sample of 26 Italian intensive care units. Crit Care Med 26:1427–1432PubMedCrossRef
6.
go back to reference Pollack MM, Ruttimann UE, Getson PR (1988) Pediatric risk of mortality (PRISM) score. Crit Care Med 16:1110–1116PubMedCrossRef Pollack MM, Ruttimann UE, Getson PR (1988) Pediatric risk of mortality (PRISM) score. Crit Care Med 16:1110–1116PubMedCrossRef
7.
go back to reference Pollack MM, Patel KM, Ruttimann UE (1996) PRISM III: an updated Pediatric Risk of Mortality score. Crit Care Med 24:743–752PubMedCrossRef Pollack MM, Patel KM, Ruttimann UE (1996) PRISM III: an updated Pediatric Risk of Mortality score. Crit Care Med 24:743–752PubMedCrossRef
8.
go back to reference Shann F, Pearson G, Slater A, Wilkinson K (1997) Paediatric index of mortality (PIM): a mortality prediction model for children in intensive care. Intensive Care Med 23:201–207PubMedCrossRef Shann F, Pearson G, Slater A, Wilkinson K (1997) Paediatric index of mortality (PIM): a mortality prediction model for children in intensive care. Intensive Care Med 23:201–207PubMedCrossRef
9.
go back to reference Slater A, Shann F, Pearson G for the PIM Study Group (2003) PIM2: a revised version of the Paediatric Index of Mortality. Intensive Care Med 29:278–285PubMed Slater A, Shann F, Pearson G for the PIM Study Group (2003) PIM2: a revised version of the Paediatric Index of Mortality. Intensive Care Med 29:278–285PubMed
10.
go back to reference Brady AR, Harrison D, Black S, Jones S, Rowan K, Pearson G, Ratcliffe J, Parry GJ, on behalf of the UK PICOS Study Group (2006) Assessment and optimization of a mortality prediction tool for admission to pediatric intensive care in the United Kingdom. Pediatrics 117:e733–742PubMedCrossRef Brady AR, Harrison D, Black S, Jones S, Rowan K, Pearson G, Ratcliffe J, Parry GJ, on behalf of the UK PICOS Study Group (2006) Assessment and optimization of a mortality prediction tool for admission to pediatric intensive care in the United Kingdom. Pediatrics 117:e733–742PubMedCrossRef
11.
go back to reference van Keulen JG, Gemke RJBJ, Polderman KH (2005) Effect of training and strict guidelines on the reliability of risk adjustment systems in paediatric intensive care. Intensive Care Med 31:1229–1234PubMedCrossRef van Keulen JG, Gemke RJBJ, Polderman KH (2005) Effect of training and strict guidelines on the reliability of risk adjustment systems in paediatric intensive care. Intensive Care Med 31:1229–1234PubMedCrossRef
12.
go back to reference Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310PubMed Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310PubMed
13.
go back to reference Hosmer DW, Lemeshow S (2000) Applied logistic regression. Wiley, New York Hosmer DW, Lemeshow S (2000) Applied logistic regression. Wiley, New York
14.
go back to reference Goldstein B, Giroir B, Randolph A and the Members of the International Consensus Conference on Pediatric Sepsis (2005) International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med 6:2–8PubMedCrossRef Goldstein B, Giroir B, Randolph A and the Members of the International Consensus Conference on Pediatric Sepsis (2005) International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med 6:2–8PubMedCrossRef
15.
go back to reference Miettinen OS (1976) Estimability and estimation in case-referent studies. Am J Epidemiol 103:226–235PubMed Miettinen OS (1976) Estimability and estimation in case-referent studies. Am J Epidemiol 103:226–235PubMed
16.
go back to reference Frey B, Argent A (2004) Safe paediatric intensive care. 1. Does more medical care lead to improved outcome? Intensive Care Med 30:1041–1046PubMedCrossRef Frey B, Argent A (2004) Safe paediatric intensive care. 1. Does more medical care lead to improved outcome? Intensive Care Med 30:1041–1046PubMedCrossRef
17.
go back to reference Frey B, Argent A (2004) Safe paediatric intensive care. 2. Workplace organisation, critical incident monitoring and guidelines. Intensive Care Med 30:1292–1297PubMed Frey B, Argent A (2004) Safe paediatric intensive care. 2. Workplace organisation, critical incident monitoring and guidelines. Intensive Care Med 30:1292–1297PubMed
18.
go back to reference Rosenberg DJ, Moss MM (2004) American College of Critical Care Medicine of the Society of Critical Care Medicine. Guidelines and levels of care for pediatric intensive care units. Crit Care Med 32:2117–2127PubMedCrossRef Rosenberg DJ, Moss MM (2004) American College of Critical Care Medicine of the Society of Critical Care Medicine. Guidelines and levels of care for pediatric intensive care units. Crit Care Med 32:2117–2127PubMedCrossRef
19.
go back to reference Kanter RK (2002) Regional variation in child mortality at hospitals lacking a pediatric intensive care unit. Crit Care Med 30:94–99PubMedCrossRef Kanter RK (2002) Regional variation in child mortality at hospitals lacking a pediatric intensive care unit. Crit Care Med 30:94–99PubMedCrossRef
20.
go back to reference Pearson G, Shann F, Barry P, Vyas J, Thomas D, Powell C, Field D (1997) Should paediatric intensive care be centralised? Trent versus Victoria. Lancet 349:1213–1217PubMedCrossRef Pearson G, Shann F, Barry P, Vyas J, Thomas D, Powell C, Field D (1997) Should paediatric intensive care be centralised? Trent versus Victoria. Lancet 349:1213–1217PubMedCrossRef
21.
go back to reference Bonati M, Campi R (2005) What can we do to improve child health in southern Italy? PLoS Med 2:e250PubMedCrossRef Bonati M, Campi R (2005) What can we do to improve child health in southern Italy? PLoS Med 2:e250PubMedCrossRef
22.
go back to reference Tibby SM, Taylor D, Festa M, Hanna S, Hatherill M, Jones G, Habibi P, Durward A, Murdoch IA (2002) A comparison of three scoring systems for mortality risk among retrieved intensive care patients. Arch Dis Child 87:421–425PubMedCrossRef Tibby SM, Taylor D, Festa M, Hanna S, Hatherill M, Jones G, Habibi P, Durward A, Murdoch IA (2002) A comparison of three scoring systems for mortality risk among retrieved intensive care patients. Arch Dis Child 87:421–425PubMedCrossRef
23.
go back to reference Nipshagen MD, Polderman KH, De Victor D, Gemke RJ (2002) Pediatric intensive care: result of a European survey. Intensive Care Med 28:1797–803PubMedCrossRef Nipshagen MD, Polderman KH, De Victor D, Gemke RJ (2002) Pediatric intensive care: result of a European survey. Intensive Care Med 28:1797–803PubMedCrossRef
24.
go back to reference Mestrovic J, Kardum G, Polic B, Omazic A, Stricevic L, Sustic A (2005) Applicability of the Australian and New Zealand Paediatric Intensive Care Registry diagnostic codes and Paediatric Index of Mortality 2 scoring system in a Croatian paediatric intensive care unit. Eur J Pediatr 164:783–784PubMedCrossRef Mestrovic J, Kardum G, Polic B, Omazic A, Stricevic L, Sustic A (2005) Applicability of the Australian and New Zealand Paediatric Intensive Care Registry diagnostic codes and Paediatric Index of Mortality 2 scoring system in a Croatian paediatric intensive care unit. Eur J Pediatr 164:783–784PubMedCrossRef
Metadata
Title
Pediatric Index of Mortality 2 score in Italy: a multicenter, prospective, observational study
Authors
Andrea Wolfler
Paolo Silvani
Massimo Musicco
Ida Salvo
Italian Pediatric Sepsis Study (SISPe) Group
Publication date
01-08-2007
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 8/2007
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-007-0694-z

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