Published in:
01-02-2007 | Correspondence
Management of autonomic dysfunction in severe tetanus: the importance of deep analgosedation
Authors:
Thomas Duning, Joerg Kraus, Darius Guenter Nabavi, Wolf-Ruediger Schaebitz
Published in:
Intensive Care Medicine
|
Issue 2/2007
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Excerpt
Although the number of cases of tetanus in the developed world is low, the mortality ranges between 20% and 50% [
1]. Even today, treatment of tetanus in developed countries is essentially symptomatic, and management regimes have not markedly reduced mortality. As modern intensive care prevents death from acute respiratory failure, autonomic instability becomes the most life-threatening complication [
1,
2]. Because of the rarity of the disease in countries with available intensive care treatment, management regimes for the effective control of critical autonomic instability are not standardised and rely mainly on instructive case reports and personal communications. …
