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Published in: Intensive Care Medicine 1/2006

01-01-2006 | Editorial

Statins: the next step in adjuvant therapy for sepsis?

Authors: Armand Mekontso-Dessap, Christian Brun-Buisson

Published in: Intensive Care Medicine | Issue 1/2006

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Excerpt

Statins are powerful hypolipemic drugs with pleiotropic effects and have been shown to improve survival in the primary and secondary prevention of atherosclerosis in numerous large randomized clinical trials [16]. Interestingly, in many of these trials, their beneficial clinical impact included noncoronary events. For example, statin therapy was consistently associated with decreased C-reactive protein (CRP) levels in recent human clinical trials, although the magnitude of this effect varied between drugs [7]. …
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Metadata
Title
Statins: the next step in adjuvant therapy for sepsis?
Authors
Armand Mekontso-Dessap
Christian Brun-Buisson
Publication date
01-01-2006
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 1/2006
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-005-2860-5

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