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At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
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Intensive Care Medicine
Published in: Intensive Care Medicine 1/2006

01-01-2006 | Correspondence

Mechanical ventilation for patients with ARDS: a UK survey on calculation of tidal volume

Authors: Rosel Tallach, Paul Jefferson, David R. Ball

Published in: Intensive Care Medicine | Issue 1/2006

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Excerpt

The ARDSnet study [1] demonstrated a 22% relative reduction in mortality using tidal volumes of 6 ml/kg (ARDSnet strategy). Tidal volumes were estimated using predicted body weight, which was calculated using an equation based on the patient’s gender and height. It has been suggested that clinicians are using actual body weight rather than predicted body weight to calculate tidal volume. Actual body weight can be up to 30% higher than predicted body weight, and this may lead to tidal volumes being used that are in excess of those recommended [2, 3]. …
Literature
1.
The Acute Respiratory Distress Syndrome Network (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. New Engl J Med 342:1301–1308CrossRefPubMed
2.
Young MP, Manning HL, Wilson DL, Mette SA, Riker RR, Leiter JC, Liu SK, Bates JT, Parsons PE (2004) Ventilation of patients with acute lung injury and acute respiratory distress syndrome: has new evidence changed clinical practice? Crit Care Med 32:1260–1265CrossRefPubMed
3.
Kam EPY, Eslick GD, James A, Benson JP (2004) Acute respiratory distress syndrome and low tidal volume ventilation: the debate about weight. Intensive Care Med 30:1502CrossRefPubMed
4.
Hughes M, MacKirdy F, Ross J, Norrie J, Grant IS (2003) Acute respiratory distress syndrome: an audit of incidence and outcome in Scottish intensive care units. Anaesthesia 58:838–845CrossRefPubMed
Metadata
Title
Mechanical ventilation for patients with ARDS: a UK survey on calculation of tidal volume
Authors
Rosel Tallach
Paul Jefferson
David R. Ball
Publication date
01-01-2006
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 1/2006
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-005-2851-6

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