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Intensive Care Medicine
Published in: Intensive Care Medicine 3/2006

01-03-2006 | Seminal Study in Intensive Care

Organ dysfunction during sepsis

Authors: Suveer Singh, Timothy W. Evans

Published in: Intensive Care Medicine | Issue 3/2006

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Abstract

Background

Multiple organ dysfunction syndrome is the commonest reason for sepsis-associated mortality.

Discussion

In the 40 years since it was first described understanding of its pathophysiology has improved, and novel methodologies for monitoring and severity of illness scoring have emerged. These, together with the development of systematic strategies for managing organ dysfunction in sepsis, and potentially effective new therapeutic interventions, should assist in reducing sepsis-associated mortality.

Conclusion

These historical developments are discussed, and the reader is directed to these references for further guidance.
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Metadata
Title
Organ dysfunction during sepsis
Authors
Suveer Singh
Timothy W. Evans
Publication date
01-03-2006
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 3/2006
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-005-0038-9

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Informed consent for research in ICU obtained before ICU admission

Original

Effects of neuromuscular block on systemic and cerebral hemodynamics and bispectral index during moderate or deep sedation in critically ill patients