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Intensive Care Medicine
Published in: Intensive Care Medicine 6/2004

01-06-2004 | Correspondence

Relapse of SARS upon tapering corticosteroid

Authors: Jung-Yien Chien, Po-Ren Hsueh, Shan-Chwen Chang, Juey-Jen Hwang, Chong-Jen Yu, Pan-Chyr Yang

Published in: Intensive Care Medicine | Issue 6/2004

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Excerpt

Sir: Corticosteroid has been generally considered beneficial for patients with severe acute respiratory syndrome (SARS), but the standard treatment protocol is still uncertain [1]. We describe a SARS patient who twice experienced relapse of SARS which was complicated with shock and acute disseminated intravascular coagulopathy (DIC) during stepping down the corticosteroid dose. …
Literature
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Peiris JS, Yuen KY, Osterhaus AD, Stohr K (2003) The severe acute respiratory syndrome. N Engl J Med 349:2431–2441CrossRefPubMed
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Nicholls JM, Poon LL, Lee KC, Ng WF, Lai ST, Leung CY, Chu CM, Hui PK, Mak KL, Lim W, Yan KW, Chan KH, Tsang NC, Guan Y, Yuen KY, Peiris JS (2003) Lung pathology of fatal severe acute respiratory syndrome. Lancet 361:1773–1778CrossRefPubMed
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So LK, Lau AC, Yam LY, Cheung TM, Poon E, Yung RW, Yuen KY (2003) Development of a standard treatment protocol for severe acute respiratory syndrome. Lancet 361:1615–1617CrossRefPubMed
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Ho JC, Ooi GC, Mok TY, Chan JW, Hung I, Lam B, Wong PC, Li PC, Ho PL, Lam WK, Ng CK, Ip MS, Lai KN, Chan-Yeung M, Tsang KW (2003) High-dose pulse versus nonpulse corticosteroid regimens in severe acute respiratory syndrome. Am J Respir Crit Care Med 168:1449–1456CrossRefPubMed
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Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ Jr (2001) Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 344:699–709PubMed
Metadata
Title
Relapse of SARS upon tapering corticosteroid
Authors
Jung-Yien Chien
Po-Ren Hsueh
Shan-Chwen Chang
Juey-Jen Hwang
Chong-Jen Yu
Pan-Chyr Yang
Publication date
01-06-2004
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 6/2004
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-004-2287-4

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