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Published in: Social Psychiatry and Psychiatric Epidemiology 11/2018

01-11-2018 | Original Paper

Which mental disorders are associated with the greatest impairment in functioning?

Authors: Mark J. Edlund, Jiantong Wang, Kristen Gulledge Brown, Valerie L. Forman-Hoffman, Sara L. Calvin, Sarra L. Hedden, Jonaki Bose

Published in: Social Psychiatry and Psychiatric Epidemiology | Issue 11/2018

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Abstract

Objective

The objective of this study is to estimate the comparative associations of mental disorders with three measures of functional impairment: the Global Assessment of Functioning (GAF); the number of days in the past 12 months of total inability to work or carry out normal activities because of emotions, nerves, or mental health (i.e., days out of role); and a modified version of the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0).

Methods

Secondary data analysis of the linked Mental Health Surveillance Study and the National Survey on Drug Use and Health (n = 5653), nationally representative population surveys conducted in the United States. Generalized linear models assessed the independent effects of mental disorders on each measure of functional impairment, controlling for mental disorder comorbidity, physical health disorders, and sociodemographic factors.

Results

The results varied across measures of functional impairment. However, mood disorders generally tended to be associated with the greatest functional impairment, anxiety disorders with intermediate impairment, and substance use disorders with the least impairment. All 15 disorders were significantly associated with the GAF score in multiple regression models, eight disorders were significantly associated with the WHODAS score, and three disorders were significantly associated with days out of role.

Conclusions

Our results highlight the value of complementary measures of functional impairment.
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Metadata
Title
Which mental disorders are associated with the greatest impairment in functioning?
Authors
Mark J. Edlund
Jiantong Wang
Kristen Gulledge Brown
Valerie L. Forman-Hoffman
Sara L. Calvin
Sarra L. Hedden
Jonaki Bose
Publication date
01-11-2018
Publisher
Springer Berlin Heidelberg
Published in
Social Psychiatry and Psychiatric Epidemiology / Issue 11/2018
Print ISSN: 0933-7954
Electronic ISSN: 1433-9285
DOI
https://doi.org/10.1007/s00127-018-1554-6

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