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Diabetologia
Published in: Diabetologia 6/2015

01-06-2015 | Letter

Impact of cancer on use of glucose-lowering drug treatment in individuals with diabetes: potential mechanisms

Author: Frans Pouwer

Published in: Diabetologia | Issue 6/2015

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Excerpt

To the Editor: In a very interesting and relevant study, based on the very large dataset from the Eindhoven Cancer Registry, Zanders et al investigated the potential impact of cancer on adherence to glucose-lowering drugs (GLDs; oral medication and/or insulin) in people with diabetes [1]. Their results showed a significant drop in the medication possession ratio, which was used as an indicator for medication adherence. The authors conclude that they found ‘a clear decline in adherence to GLD treatment regimens following a cancer diagnosis’. They state that the reason for this decline needs to be further elucidated. …
Literature
1.
Zanders MM, Haak HR, van Herk-Sukel MPP, van de Poll-Franse LV, Johnson JA (2015) Impact of cancer on adherence to glucose-lowering drug treatment in individuals with diabetes. Diabetologia. doi:10.​1007/​s00125-015-3497-8
2.
3.
Lim EL, Hollingsworth KG, Aribisala BS, Chen MJ, Mathers JC, Taylor R (2011) Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol. Diabetologia 54:2506–2514CrossRefPubMedCentralPubMed
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Nicolini A, Ferrari P, Masoni MC et al (2013) Malnutrition, anorexia and cachexia in cancer patients: a mini-review on pathogenesis and treatment. Biomed Pharmacother 67:807–817CrossRefPubMed
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Ng CG, Boks MP, Zainal NZ, de Wit NJ (2011) The prevalence and pharmacotherapy of depression in cancer patients. J Affect Disord 131:1–7CrossRefPubMed
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Pouwer F, Nefs G, Nouwen A (2013) Adverse effects of depression on glycemic control and health outcomes in people with diabetes: a review. Endocrinol Metab Clin North Am 42:529–544CrossRefPubMed
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Van Dooren FE, Nefs G, Schram MT, Verhey FR, Denollet J, Pouwer F (2013) Depression and risk of mortality in people with diabetes mellitus: a systematic review and meta-analysis. PLoS One 8:e57058CrossRefPubMedCentralPubMed
Metadata
Title
Impact of cancer on use of glucose-lowering drug treatment in individuals with diabetes: potential mechanisms
Author
Frans Pouwer
Publication date
01-06-2015
Publisher
Springer Berlin Heidelberg
Published in
Diabetologia / Issue 6/2015
Print ISSN: 0012-186X
Electronic ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-015-3560-5

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