Skip to main content
Top
Published in: Diabetologia 4/2010

Open Access 01-04-2010 | Commentary

Sense and nonsense in sensors

Authors: J. Hermanides, J. H. DeVries

Published in: Diabetologia | Issue 4/2010

Login to get access

Abstract

Continuous subcutaneous glucose monitoring (CGM) is a developing technology in the treatment of diabetes mellitus. The first randomised controlled trials on its efficacy have been performed. In several studies, CGM lowered HbA1c in adult patients with suboptimally controlled type 1 diabetes mellitus, when selecting compliant patients who tolerate the device. However, as a preventive tool for hypoglycaemia, CGM has not fulfilled the great expectations. Increasing reimbursement of CGM is expected in the near future, awaiting studies on cost-effectiveness.
Literature
2.
go back to reference Bolinder J, Ungerstedt U, Arner P (1993) Long-term continuous glucose monitoring with microdialysis in ambulatory insulin-dependent diabetic patients. Lancet 342:1080–1085CrossRefPubMed Bolinder J, Ungerstedt U, Arner P (1993) Long-term continuous glucose monitoring with microdialysis in ambulatory insulin-dependent diabetic patients. Lancet 342:1080–1085CrossRefPubMed
3.
go back to reference Bolinder J, Ungerstedt U, Arner P (1992) Microdialysis measurement of the absolute glucose concentration in subcutaneous adipose tissue allowing glucose monitoring in diabetic patients. Diabetologia 35:1177–1180CrossRefPubMed Bolinder J, Ungerstedt U, Arner P (1992) Microdialysis measurement of the absolute glucose concentration in subcutaneous adipose tissue allowing glucose monitoring in diabetic patients. Diabetologia 35:1177–1180CrossRefPubMed
4.
go back to reference American Diabetes Association (2008) Standards of medical care in diabetes—2008. Diabetes Care 31:S12–S54CrossRef American Diabetes Association (2008) Standards of medical care in diabetes—2008. Diabetes Care 31:S12–S54CrossRef
6.
go back to reference Wentholt IM, Maran A, Masurel N, Heine RJ, Hoekstra JB, DeVries JH (2007) Nocturnal hypoglycaemia in type 1 diabetic patients, assessed with continuous glucose monitoring: frequency, duration and associations. Diabet Med 24:527–532CrossRefPubMed Wentholt IM, Maran A, Masurel N, Heine RJ, Hoekstra JB, DeVries JH (2007) Nocturnal hypoglycaemia in type 1 diabetic patients, assessed with continuous glucose monitoring: frequency, duration and associations. Diabet Med 24:527–532CrossRefPubMed
7.
go back to reference Hanaire H (2006) Continuous glucose monitoring and external insulin pump: towards a subcutaneous closed loop. Diabetes Metab 32:534–538CrossRefPubMed Hanaire H (2006) Continuous glucose monitoring and external insulin pump: towards a subcutaneous closed loop. Diabetes Metab 32:534–538CrossRefPubMed
8.
go back to reference Gross TM, Bode BW, Einhorn D et al (2000) Performance evaluation of the MiniMed continuous glucose monitoring system during patient home use. Diabetes Technol Ther 2:49–56CrossRefPubMed Gross TM, Bode BW, Einhorn D et al (2000) Performance evaluation of the MiniMed continuous glucose monitoring system during patient home use. Diabetes Technol Ther 2:49–56CrossRefPubMed
9.
go back to reference Deiss D, Bolinder J, Riveline JP et al (2006) Improved glycemic control in poorly controlled patients with type 1 diabetes using real-time continuous glucose monitoring. Diabetes Care 29:2730–2732CrossRefPubMed Deiss D, Bolinder J, Riveline JP et al (2006) Improved glycemic control in poorly controlled patients with type 1 diabetes using real-time continuous glucose monitoring. Diabetes Care 29:2730–2732CrossRefPubMed
10.
go back to reference Hirsch IB, Abelseth J, Bode BW et al (2008) Sensor-augmented insulin pump therapy: results of the first randomized treat-to-target study. Diabetes Technol Ther 10:377–383CrossRefPubMed Hirsch IB, Abelseth J, Bode BW et al (2008) Sensor-augmented insulin pump therapy: results of the first randomized treat-to-target study. Diabetes Technol Ther 10:377–383CrossRefPubMed
11.
go back to reference The Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group (2008) Continuous glucose monitoring and intensive treatment of type 1 diabetes. N Engl J Med 359:1464–1476CrossRef The Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group (2008) Continuous glucose monitoring and intensive treatment of type 1 diabetes. N Engl J Med 359:1464–1476CrossRef
12.
go back to reference Raccah D, Sulmont V, Reznik Y et al (2009) Incremental value of continuous glucose monitoring when starting pump therapy in patients with poorly controlled type 1 diabetes: the RealTrend study. Diabetes Care 32:2245–2250CrossRefPubMed Raccah D, Sulmont V, Reznik Y et al (2009) Incremental value of continuous glucose monitoring when starting pump therapy in patients with poorly controlled type 1 diabetes: the RealTrend study. Diabetes Care 32:2245–2250CrossRefPubMed
13.
go back to reference Hermanides J, Nørgaard K, Bruttomesso D et al (2009) Sensor augmented pump therapy substantially lowers HbA1c. Diabetologia 52:S43 (Abstract) Hermanides J, Nørgaard K, Bruttomesso D et al (2009) Sensor augmented pump therapy substantially lowers HbA1c. Diabetologia 52:S43 (Abstract)
14.
go back to reference Cryer PE (2004) Diverse causes of hypoglycemia-associated autonomic failure in diabetes. N Engl J Med 350:2272–2279CrossRefPubMed Cryer PE (2004) Diverse causes of hypoglycemia-associated autonomic failure in diabetes. N Engl J Med 350:2272–2279CrossRefPubMed
15.
go back to reference Wentholt IM, Hoekstra JB, DeVries JH (2007) Continuous glucose monitors: the long-awaited watch dogs? Diabetes Technol Ther 9:399–409CrossRefPubMed Wentholt IM, Hoekstra JB, DeVries JH (2007) Continuous glucose monitors: the long-awaited watch dogs? Diabetes Technol Ther 9:399–409CrossRefPubMed
16.
go back to reference Wentholt IM, Hart AA, Hoekstra JB, DeVries JH (2007) Relationship between interstitial and blood glucose in type 1 diabetes patients: delay and the push-pull phenomenon revisited. Diabetes Technol Ther 9:169–175CrossRefPubMed Wentholt IM, Hart AA, Hoekstra JB, DeVries JH (2007) Relationship between interstitial and blood glucose in type 1 diabetes patients: delay and the push-pull phenomenon revisited. Diabetes Technol Ther 9:169–175CrossRefPubMed
18.
go back to reference Roze S, Valentine WJ, Zakrzewska KE, Palmer AJ (2005) Health-economic comparison of continuous subcutaneous insulin infusion with multiple daily injection for the treatment of type 1 diabetes in the UK. Diabet Med 22:1239–1245CrossRefPubMed Roze S, Valentine WJ, Zakrzewska KE, Palmer AJ (2005) Health-economic comparison of continuous subcutaneous insulin infusion with multiple daily injection for the treatment of type 1 diabetes in the UK. Diabet Med 22:1239–1245CrossRefPubMed
19.
go back to reference Yoo HJ, An HG, Park SY et al (2008) Use of a real time continuous glucose monitoring system as a motivational device for poorly controlled type 2 diabetes. Diabetes Res Clin Pract 82:73–79CrossRefPubMed Yoo HJ, An HG, Park SY et al (2008) Use of a real time continuous glucose monitoring system as a motivational device for poorly controlled type 2 diabetes. Diabetes Res Clin Pract 82:73–79CrossRefPubMed
20.
go back to reference Landon MB, Gabbe SG, Piana R, Mennuti MT, Main EK (1987) Neonatal morbidity in pregnancy complicated by diabetes mellitus: predictive value of maternal glycemic profiles. Am J Obstet Gynecol 156:1089–1095PubMed Landon MB, Gabbe SG, Piana R, Mennuti MT, Main EK (1987) Neonatal morbidity in pregnancy complicated by diabetes mellitus: predictive value of maternal glycemic profiles. Am J Obstet Gynecol 156:1089–1095PubMed
21.
go back to reference Murphy HR, Rayman G, Lewis K et al (2008) Effectiveness of continuous glucose monitoring in pregnant women with diabetes: randomised clinical trial. BMJ 337:a1680CrossRefPubMed Murphy HR, Rayman G, Lewis K et al (2008) Effectiveness of continuous glucose monitoring in pregnant women with diabetes: randomised clinical trial. BMJ 337:a1680CrossRefPubMed
22.
go back to reference Sair MPMF, Etherington PJB, Peter Winlove CD, Evans TWM (2001) Tissue oxygenation and perfusion in patients with systemic sepsis. Crit Care Med 29:1343–1349CrossRefPubMed Sair MPMF, Etherington PJB, Peter Winlove CD, Evans TWM (2001) Tissue oxygenation and perfusion in patients with systemic sepsis. Crit Care Med 29:1343–1349CrossRefPubMed
Metadata
Title
Sense and nonsense in sensors
Authors
J. Hermanides
J. H. DeVries
Publication date
01-04-2010
Publisher
Springer-Verlag
Published in
Diabetologia / Issue 4/2010
Print ISSN: 0012-186X
Electronic ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-009-1649-4

Other articles of this Issue 4/2010

Diabetologia 4/2010 Go to the issue