Duration of diabetes, glucose control and cardiovascular risk

Excerpt

To the Editor: We read with great interest the meta-analysis by the Collaborators on Trials of Lowering Glucose (CONTROL) Group of recent trials examining the impact of intensive glycaemic control on cardiovascular risk in people with type 2 diabetes mellitus [1]. This well executed study analysed data on 27,049 patients in four important recently published prospective trials, the Action to Control Cardiovascular Risk in Diabetes (ACCORD) study [2], the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) study [3], the Veterans Affairs Diabetes Trial (VADT) [4] and the United Kingdom Prospective Diabetes Study (UKPDS) [5]. …