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Diabetologia
Published in: Diabetologia 10/2004

01-10-2004 | Commentary

From beast to bedside: a commentary

Author: A. A. Rossini

Published in: Diabetologia | Issue 10/2004

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Excerpt

Diabetes mellitus comprises a group of disorders, the common feature of which is hyperglycaemia. This may be due to near-absolute deficiency of insulin (Type 1 diabetes) or to relative deficiency of insulin (Type 2 diabetes). …
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Sutherland DE, Sibley R, Xu XZ et al. (1984) Twin-to-twin pancreas transplantation: reversal and reenactment of the pathogenesis of type I diabetes. Trans Assoc Am Physicians 97:80–87PubMed
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Banting FG, Best DH, Collip JB, Campbell WR, Fletcher AA (1922) Pancreatic extracts in the treatment of diabetes mellitus. Preliminary report. CMAJ 22:141–146
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Rossini AA, Mordes JP (1992) Insulin dependent diabetes mellitus, experimental models. In: Roitt IM (ed) Encyclopedia of immunology. Academic Press, San Diego, pp 872–877
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Mordes JP, Serreze DV, Greiner DL, Rossini AA (2004) Animal models of autoimmune diabetes mellitus. In: LeRoith D, Taylor SI, Olefsky JM (eds) Diabetes mellitus. A fundamental and clinical text, 3rd edn. Lippincott Williams & Wilkins, Philadelphia, pp 591–610
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Sorli CH, Greiner DL, Mordes JP, Rossini AA (1998) Stem cell transplantation for treatment of autoimmune diseases. Graft 1:71–81
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Waterland RA, Jirtle RL (2003) Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol 23:5293–5300CrossRefPubMed
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Rossini AA, Mordes JP, Handler ES (1988) Speculations on etiology of diabetes mellitus: tumbler hypothesis. Diabetes 37:257–261PubMed
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Renold AE, Porte D Jr, Shafrir E (1988) Definitions for diabetes types: use and abuse of the concept ‘animal models of diabetes mellitus’. In: Shafrir E, Renold AE (eds) Frontiers in diabetes research. Lessons from animal diabetes II. John Libbey & Co, London, pp 3–7
Metadata
Title
From beast to bedside: a commentary
Author
A. A. Rossini
Publication date
01-10-2004
Publisher
Springer-Verlag
Published in
Diabetologia / Issue 10/2004
Print ISSN: 0012-186X
Electronic ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-004-1519-z

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Keynote webinar | Spotlight on medication adherence

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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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