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Published in: Diabetologia 7/2004

01-07-2004 | Author’s Reply

Reply to Comment on: Hales CN, Ozanne SE (2003) For Debate: Fetal and early postnatal growth restriction lead to diabetes, the metabolic syndrome and renal failure

Authors: C. N. Hales, S. E. Ozanne

Published in: Diabetologia | Issue 7/2004

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Excerpt

To the Editor: We are grateful to Plagemann et al. for their constructive comments on wider aspects of the field we discussed in our article. The title and main substance of our article was a factual summary of the results of our experiments on rats, involving feeding rat dams a low-protein diet during pregnancy and lactation. This manipulation results in fetal and early postnatal growth restriction. It was not our intention to review all of the literature in this field, but rather, in an invited lecture, to review the progress of our own research. We apologise if we caused unrest by the focus of our article. We did not state that low birthweight is a cause of adult obesity, although there are data to suggest that this is true in some circumstances. …
Literature
1.
go back to reference McCance DR, Pettitt DJ, Hanson RL et al. (1994) Birth weight and non-insulin dependent diabetes: ‘thrifty genotype’, ‘thrifty phenotype’, or ‘surviving small baby genotype’. BMJ 308:942–945CrossRefPubMedPubMedCentral McCance DR, Pettitt DJ, Hanson RL et al. (1994) Birth weight and non-insulin dependent diabetes: ‘thrifty genotype’, ‘thrifty phenotype’, or ‘surviving small baby genotype’. BMJ 308:942–945CrossRefPubMedPubMedCentral
3.
go back to reference Ozanne SE, Wang CL, Coleman N et al. (1996) Altered muscle insulin sensitivity in the male offspring of protein malnourished rats. Am J Physiol 271:E1128–E1134PubMed Ozanne SE, Wang CL, Coleman N et al. (1996) Altered muscle insulin sensitivity in the male offspring of protein malnourished rats. Am J Physiol 271:E1128–E1134PubMed
4.
go back to reference Oscai LP, McGarr JA (1978) Evidence that the amount of food consumed in early life fixes appetite in the rat. Am J Physiol 235:R141–R144PubMed Oscai LP, McGarr JA (1978) Evidence that the amount of food consumed in early life fixes appetite in the rat. Am J Physiol 235:R141–R144PubMed
5.
go back to reference Ozanne SE, Lewis R, Jennings BJ, Hales CN (2004) Early programming of weight gain in mice prevents the induction of obesity by a highly palatable diet. Clin Sci 106:141–145CrossRefPubMed Ozanne SE, Lewis R, Jennings BJ, Hales CN (2004) Early programming of weight gain in mice prevents the induction of obesity by a highly palatable diet. Clin Sci 106:141–145CrossRefPubMed
7.
go back to reference Barker DJP, Hales CN, Fall CHD et al. (1993) Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyper-lipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia 36:62–67CrossRefPubMed Barker DJP, Hales CN, Fall CHD et al. (1993) Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyper-lipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia 36:62–67CrossRefPubMed
Metadata
Title
Reply to Comment on: Hales CN, Ozanne SE (2003) For Debate: Fetal and early postnatal growth restriction lead to diabetes, the metabolic syndrome and renal failure
Authors
C. N. Hales
S. E. Ozanne
Publication date
01-07-2004
Publisher
Springer Berlin Heidelberg
Published in
Diabetologia / Issue 7/2004
Print ISSN: 0012-186X
Electronic ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-004-1445-0

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