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Published in: European Journal of Trauma and Emergency Surgery 6/2022

Open Access 03-12-2021 | Central Nervous System Trauma | Original Article

Comparison of the predictive value of two international guidelines for safe discharge of patients with mild traumatic brain injuries and associated intracranial pathology

Authors: Sebastian Vestlund, Sebastian Tryggmo, Tomas Vedin, Per-Anders Larsson, Marcus Edelhamre

Published in: European Journal of Trauma and Emergency Surgery | Issue 6/2022

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Abstract

Purpose

To determine and compare the sensitivity, specificity, and proportion of patients eligible for discharge by the Brain Injury Guidelines and the Mild TBI Risk Score in patients with mild traumatic brain injury and concomitant intracranial injury.

Methods

Retrospective review of the medical records of adult patients with traumatic intracranial injuries and an initial Glasgow Coma Scale score of 14–15, who sought care at Helsingborg Hospital between 2014/01/01 and 2019/12/31. Both guidelines were theoretically applied. The sensitivity, specificity, and percentage of the cohort that theoretically could have been discharged by either guideline were calculated. The outcome was defined as death, in-hospital intervention, admission to the intensive care unit, requiring emergency intubation due to intracranial injury, decreased consciousness, or seizure within 30 days of presentation.

Results

Of the 538 patients included, 8 (1.5%) and 10 (1.9%) were eligible for discharge according to the Brain Injury Guidelines and the Mild TBI Risk Score, respectively. Both guidelines had a sensitivity of 100%. The Brain Injury Guidelines had a specificity of 2.3% and the Mild TBI Risk Score had a specificity of 2.9%.

Conclusion

There was no difference between the two guidelines in sensitivity, specificity, or proportion of the cohort eligible for discharge. Specificity and proportion of cohort eligible for discharge were lower than each guideline’s original study. At present, neither guideline can be recommended for implementation in the current or similar settings.
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Literature
1.
go back to reference Dewan MC, et al. Estimating the global incidence of traumatic brain injury. J Neurosurg. 2019;130(4):1080–97.CrossRef Dewan MC, et al. Estimating the global incidence of traumatic brain injury. J Neurosurg. 2019;130(4):1080–97.CrossRef
2.
go back to reference Brazinova A, et al. Epidemiology of traumatic brain injury in europe: a living systematic review. J Neurotrauma. 2018;38(10):1411.CrossRefPubMed Brazinova A, et al. Epidemiology of traumatic brain injury in europe: a living systematic review. J Neurotrauma. 2018;38(10):1411.CrossRefPubMed
3.
go back to reference Tagliaferri F, Compagnone C, Korsic M, Servadei F, Kraus J. A systematic review of brain injury epidemiology in Europe. Acta Neurochir (Wien). 2006;148(3):255–67.CrossRefPubMed Tagliaferri F, Compagnone C, Korsic M, Servadei F, Kraus J. A systematic review of brain injury epidemiology in Europe. Acta Neurochir (Wien). 2006;148(3):255–67.CrossRefPubMed
4.
go back to reference National Center for Injury Prevention and Control (2003) Report to congress on mild traumatic brain injury in the united states: steps to prevent a serious public health problem National Center for Injury Prevention and Control (2003) Report to congress on mild traumatic brain injury in the united states: steps to prevent a serious public health problem
5.
go back to reference Teasdale G, Jennett B. Assessment of coma and impaired consciousness—a practical scale. Lancet. 1974;304(7872):81–4.CrossRef Teasdale G, Jennett B. Assessment of coma and impaired consciousness—a practical scale. Lancet. 1974;304(7872):81–4.CrossRef
6.
go back to reference Stiell IG, et al. The Canadian CT Head Rule for patients with minor head injury. Lancet. 2001;357(9266):1391–6.CrossRefPubMed Stiell IG, et al. The Canadian CT Head Rule for patients with minor head injury. Lancet. 2001;357(9266):1391–6.CrossRefPubMed
7.
go back to reference Haydel MJ, Preston CA, Mills TJ, Luber S, Blaudeau E, DeBlieux PM. Indications for computed tomography in patients with minor head injury. N Engl J Med. 2000;343(2):100–5.CrossRefPubMed Haydel MJ, Preston CA, Mills TJ, Luber S, Blaudeau E, DeBlieux PM. Indications for computed tomography in patients with minor head injury. N Engl J Med. 2000;343(2):100–5.CrossRefPubMed
8.
go back to reference Marincowitz C, Lecky FE, Townend W, Borakati A, Fabbri A, Sheldon TA. The risk of deterioration in GCS13–15 patients with traumatic brain injury identified by computed tomography imaging: a systematic review and meta-analysis. J Neurotrauma. 2018;35(5):703–18.CrossRefPubMedPubMedCentral Marincowitz C, Lecky FE, Townend W, Borakati A, Fabbri A, Sheldon TA. The risk of deterioration in GCS13–15 patients with traumatic brain injury identified by computed tomography imaging: a systematic review and meta-analysis. J Neurotrauma. 2018;35(5):703–18.CrossRefPubMedPubMedCentral
9.
go back to reference Nishijima DK, Sena MJ, Holmes JF. Identification of low-risk patients with traumatic brain injury and intracranial hemorrhage who do not need intensive care unit admission. J Trauma. 2011;70(6):101–7. Nishijima DK, Sena MJ, Holmes JF. Identification of low-risk patients with traumatic brain injury and intracranial hemorrhage who do not need intensive care unit admission. J Trauma. 2011;70(6):101–7.
10.
go back to reference Bee TK, et al. Necessity of repeat head CT and ICU monitoring in patients with minimal brain injury. J Trauma Inj Infect Crit Care. 2009;66(4):1015–8.CrossRef Bee TK, et al. Necessity of repeat head CT and ICU monitoring in patients with minimal brain injury. J Trauma Inj Infect Crit Care. 2009;66(4):1015–8.CrossRef
11.
go back to reference Stippler M, et al. Pathway-based reduction of repeat head computed tomography for patients with complicated mild traumatic brain injury: implementation and outcomes. Neurosurgery. 2021;88(4):773–8.CrossRefPubMedPubMedCentral Stippler M, et al. Pathway-based reduction of repeat head computed tomography for patients with complicated mild traumatic brain injury: implementation and outcomes. Neurosurgery. 2021;88(4):773–8.CrossRefPubMedPubMedCentral
12.
go back to reference Root BK, Kanter JH, Calnan DC, Reyes-Zaragosa M, Gill HS, Lanter PL. Emergency department observation of mild traumatic brain injury with minor radiographic findings: shorter stays, less expensive, and no increased risk compared to hospital admission. J Am Coll Emerg Physicians Open. 2020;1(4):609–17.CrossRefPubMedPubMedCentral Root BK, Kanter JH, Calnan DC, Reyes-Zaragosa M, Gill HS, Lanter PL. Emergency department observation of mild traumatic brain injury with minor radiographic findings: shorter stays, less expensive, and no increased risk compared to hospital admission. J Am Coll Emerg Physicians Open. 2020;1(4):609–17.CrossRefPubMedPubMedCentral
13.
go back to reference Joseph B, et al. The BIG (brain injury guidelines) project: defining the management of traumatic brain injury by acute care surgeons. J Trauma Acute Care Surg. 2014;76(4):965–9.CrossRefPubMed Joseph B, et al. The BIG (brain injury guidelines) project: defining the management of traumatic brain injury by acute care surgeons. J Trauma Acute Care Surg. 2014;76(4):965–9.CrossRefPubMed
14.
go back to reference Joseph B, et al. Prospective validation of the brain injury guidelines. J Trauma Acute Care Surg. 2014;77(6):984–8.CrossRefPubMed Joseph B, et al. Prospective validation of the brain injury guidelines. J Trauma Acute Care Surg. 2014;77(6):984–8.CrossRefPubMed
15.
go back to reference Marincowitz C, et al. Development of a clinical decision rule for the early safe discharge of patients with mild traumatic brain injury and findings on computed tomography brain scan: a retrospective cohort study. J Neurotrauma. 2020;37(2):324–33.CrossRefPubMed Marincowitz C, et al. Development of a clinical decision rule for the early safe discharge of patients with mild traumatic brain injury and findings on computed tomography brain scan: a retrospective cohort study. J Neurotrauma. 2020;37(2):324–33.CrossRefPubMed
16.
go back to reference Starmark JE, Stålhammar D, Holmgren E. The Reaction Level Scale (RLS 85)—manual and guidelines. Acta Neurochir (Wien). 1988;91(1–2):12–20.CrossRefPubMed Starmark JE, Stålhammar D, Holmgren E. The Reaction Level Scale (RLS 85)—manual and guidelines. Acta Neurochir (Wien). 1988;91(1–2):12–20.CrossRefPubMed
17.
go back to reference Vergouwe Y, Steyerberg EW, Eijkemans MJC, Habbema JDF. Substantial effective sample sizes were required for external validation studies of predictive logistic regression models. J Clin Epidemiol. 2005;58(5):475–83.CrossRefPubMed Vergouwe Y, Steyerberg EW, Eijkemans MJC, Habbema JDF. Substantial effective sample sizes were required for external validation studies of predictive logistic regression models. J Clin Epidemiol. 2005;58(5):475–83.CrossRefPubMed
18.
go back to reference Collins GS, Ogundimu EO, Altman DG. Sample size considerations for the external validation of a multivariable prognostic model: a resampling study. Stat Med. 2016;35(2):214–26.CrossRefPubMed Collins GS, Ogundimu EO, Altman DG. Sample size considerations for the external validation of a multivariable prognostic model: a resampling study. Stat Med. 2016;35(2):214–26.CrossRefPubMed
19.
go back to reference Huynh T, Jacobs DG, Dix S, Sing RF, Miles WS, Thomason MH. Utility of neurosurgical consultation for mild traumatic brain injury. Am Surg. 2006;72(12):1162–5.CrossRefPubMed Huynh T, Jacobs DG, Dix S, Sing RF, Miles WS, Thomason MH. Utility of neurosurgical consultation for mild traumatic brain injury. Am Surg. 2006;72(12):1162–5.CrossRefPubMed
20.
go back to reference Joseph B, et al. The acute care surgery model: managing traumatic brain injury without an inpatient neurosurgical consultation. J Trauma Acute Care Surg. 2013;75(1):102–5.CrossRefPubMed Joseph B, et al. The acute care surgery model: managing traumatic brain injury without an inpatient neurosurgical consultation. J Trauma Acute Care Surg. 2013;75(1):102–5.CrossRefPubMed
21.
go back to reference Lewis PR, et al. Routine neurosurgical consultation is not necessary in mild blunt traumatic brain injury. J Trauma Acute Care Surg. 2017;82(4):776–80.CrossRefPubMed Lewis PR, et al. Routine neurosurgical consultation is not necessary in mild blunt traumatic brain injury. J Trauma Acute Care Surg. 2017;82(4):776–80.CrossRefPubMed
22.
go back to reference Dolatabadi AA, et al. Interpretation of computed tomography of the head: Emergency physicians versus radiologists. Trauma Mon. 2013;18(2):86–9.CrossRef Dolatabadi AA, et al. Interpretation of computed tomography of the head: Emergency physicians versus radiologists. Trauma Mon. 2013;18(2):86–9.CrossRef
23.
go back to reference Lee B, Whitehead MT. Radiology reports: what YOU think you’re saying and what THEY think you’re saying. Curr Probl Diagn Radiol. 2017;46(3):186–95.CrossRefPubMed Lee B, Whitehead MT. Radiology reports: what YOU think you’re saying and what THEY think you’re saying. Curr Probl Diagn Radiol. 2017;46(3):186–95.CrossRefPubMed
24.
go back to reference Plumb AAO, Grieve FM, Khan SH. Survey of hospital clinicians’ preferences regarding the format of radiology reports. Clin Radiol. 2009;64(4):386–94.CrossRefPubMed Plumb AAO, Grieve FM, Khan SH. Survey of hospital clinicians’ preferences regarding the format of radiology reports. Clin Radiol. 2009;64(4):386–94.CrossRefPubMed
26.
go back to reference Schwartz LH, Panicek DM, Berk AR, Li Y, Hricak H. Improving communication of diagnostic radiology findings through structured reporting. Radiology. 2011;260(1):174–81.CrossRefPubMedPubMedCentral Schwartz LH, Panicek DM, Berk AR, Li Y, Hricak H. Improving communication of diagnostic radiology findings through structured reporting. Radiology. 2011;260(1):174–81.CrossRefPubMedPubMedCentral
Metadata
Title
Comparison of the predictive value of two international guidelines for safe discharge of patients with mild traumatic brain injuries and associated intracranial pathology
Authors
Sebastian Vestlund
Sebastian Tryggmo
Tomas Vedin
Per-Anders Larsson
Marcus Edelhamre
Publication date
03-12-2021
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Trauma and Emergency Surgery / Issue 6/2022
Print ISSN: 1863-9933
Electronic ISSN: 1863-9941
DOI
https://doi.org/10.1007/s00068-021-01842-6

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