Skip to main content
Top
Published in: European Journal of Trauma and Emergency Surgery 6/2015

01-12-2015 | Original Article

Decreased muscle strength is associated with impaired long-term functional outcome after intramedullary nailing of femoral shaft fracture

Authors: P. Larsen, R. Elsoe, T. Graven-Nielsen, U. Laessoe, S. Rasmussen

Published in: European Journal of Trauma and Emergency Surgery | Issue 6/2015

Login to get access

Abstract

Purpose

To examine the long-term outcome after intramedullary nailing of femoral diaphysial fractures measured as disease-specific patient reported function, walking ability, muscle strength, pain and quality of life (QOL).

Methods

Cross-sectional study. Retrospective review and follow-up with clinical examination of 48 patients treated with intramedullary nailing after femoral shaft fracture between 2007 and 2010. The patients underwent a clinical examination and assessment of walking ability, maximal muscle strength during knee flexion and extension and hip abduction. Hip disability and Osteoarthritis Outcome Score (HOOS) and questionnaire evaluating QOL (Eq5D–5L) were completed by patients.

Results

Fourty-eight patients agreed to participate. Mean time for follow-up was 4.7 years. The mean HOOS scores were 84.9 (Pain), 86.6 (ADL), 85.0 (Symptoms), 72.6 (QOL), and 69.1 (Sport). The mean muscle strength of knee flexion with the injured leg (226.0 N) was significantly lower then knee flexion with the non-injured leg (259.5 N, P < 0.0001). Likewise for knee extension (335.2 vs 406.4 N, P < 0.001) and hip abduction (129.2 vs 156.0 N, P < 0.001). Significant association between HOOS and an increase in the difference in muscle strength were observed as well as between worse HOOS outcome and increasing body mass index.

Conclusion

This study showed that decreased muscle strength for knee flexion, knee extension and hip abduction was associated with worse long-term functional outcome measured with a disease-specific questionnaire (HOOS) after intramedullary nailing of femoral shaft fracture.
Literature
1.
go back to reference Helmy N, Jando VT, Lu T, et al. Muscle function and functional outcome following standard antegrade reamed intramedullary nailing of isolated femoral shaft fractures. J Orthop Trauma. 2008;22:10–5.CrossRefPubMed Helmy N, Jando VT, Lu T, et al. Muscle function and functional outcome following standard antegrade reamed intramedullary nailing of isolated femoral shaft fractures. J Orthop Trauma. 2008;22:10–5.CrossRefPubMed
2.
go back to reference Gugala Z, Qaisi YT, Hipp JA, Lindsey RW. Long-term functional implications of the iatrogenic rotational malalignment of healed diaphyseal femur fractures following intramedullary nailing. Clin Biomech (Bristol, Avon). 2011;26:274–7.CrossRef Gugala Z, Qaisi YT, Hipp JA, Lindsey RW. Long-term functional implications of the iatrogenic rotational malalignment of healed diaphyseal femur fractures following intramedullary nailing. Clin Biomech (Bristol, Avon). 2011;26:274–7.CrossRef
3.
go back to reference Ricci WM, Bellabarba C, Evanoff B, et al. Retrograde versus antegrade nailing of femoral shaft fractures. J Orthop Trauma. 2001;15:161–9.CrossRefPubMed Ricci WM, Bellabarba C, Evanoff B, et al. Retrograde versus antegrade nailing of femoral shaft fractures. J Orthop Trauma. 2001;15:161–9.CrossRefPubMed
4.
go back to reference Kapp W, Lindsey RW, Noble PC, et al. Long-term residual musculoskeletal deficits after femoral shaft fractures treated with intramedullary nailing. J Trauma. 2000;49:446–9.CrossRefPubMed Kapp W, Lindsey RW, Noble PC, et al. Long-term residual musculoskeletal deficits after femoral shaft fractures treated with intramedullary nailing. J Trauma. 2000;49:446–9.CrossRefPubMed
5.
go back to reference Deepak MK, Jain K, Rajamanya KA, et al. Functional outcome of diaphyseal fractures of femur managed by closed intramedullary interlocking nailing in adults. Ann Afr Med. 2012;11:52–7.CrossRefPubMed Deepak MK, Jain K, Rajamanya KA, et al. Functional outcome of diaphyseal fractures of femur managed by closed intramedullary interlocking nailing in adults. Ann Afr Med. 2012;11:52–7.CrossRefPubMed
6.
go back to reference Ozdemir B, Akesen B, Demirag B, et al. Long-term outcome of unreamed intramedullary nails in femur diaphyseal fractures. Ulus Travma Acil Cerrahi Derg. 2012;18:147–52.CrossRefPubMed Ozdemir B, Akesen B, Demirag B, et al. Long-term outcome of unreamed intramedullary nails in femur diaphyseal fractures. Ulus Travma Acil Cerrahi Derg. 2012;18:147–52.CrossRefPubMed
7.
go back to reference Brumback RJ, Toal TR Jr, Murphy-Zane MS, et al. Immediate weight-bearing after treatment of a comminuted fracture of the femoral shaft with a statically locked intramedullary nail. J Bone Joint Surg Am. 1999;81:1538–44.PubMed Brumback RJ, Toal TR Jr, Murphy-Zane MS, et al. Immediate weight-bearing after treatment of a comminuted fracture of the femoral shaft with a statically locked intramedullary nail. J Bone Joint Surg Am. 1999;81:1538–44.PubMed
8.
go back to reference Weiss RJ, Montgomery SM, Al Dabbagh Z, Jansson KA. National data of 6409 Swedish inpatients with femoral shaft fractures: stable incidence between 1998 and 2004. Injury. 2009;40:304–8. Weiss RJ, Montgomery SM, Al Dabbagh Z, Jansson KA. National data of 6409 Swedish inpatients with femoral shaft fractures: stable incidence between 1998 and 2004. Injury. 2009;40:304–8.
9.
go back to reference Enninghorst N, McDougall D, Evans JA. Population-based epidemiology of femur shaft fractures. J Trauma Acute Care Surg. 2013;74:1516–20.CrossRefPubMed Enninghorst N, McDougall D, Evans JA. Population-based epidemiology of femur shaft fractures. J Trauma Acute Care Surg. 2013;74:1516–20.CrossRefPubMed
10.
go back to reference Paterno MV, Archdeacon MT. Is there a standard rehabilitation protocol after femoral intramedullary nailing? J Orthop Trauma. 2009;23:S39–46.CrossRefPubMed Paterno MV, Archdeacon MT. Is there a standard rehabilitation protocol after femoral intramedullary nailing? J Orthop Trauma. 2009;23:S39–46.CrossRefPubMed
11.
go back to reference Paterno MV, Archdeacon MT, Ford KR, et al. Early rehabilitation following surgical fixation of a femoral shaft fracture. Phys Ther. 2006;86:558–72.PubMed Paterno MV, Archdeacon MT, Ford KR, et al. Early rehabilitation following surgical fixation of a femoral shaft fracture. Phys Ther. 2006;86:558–72.PubMed
12.
go back to reference Wolinsky P, Tejwani N, Richmond JH, et al. Controversies in intramedullary nailing of femoral shaft fractures. Instr Course Lect. 2002;51:291–303.PubMed Wolinsky P, Tejwani N, Richmond JH, et al. Controversies in intramedullary nailing of femoral shaft fractures. Instr Course Lect. 2002;51:291–303.PubMed
13.
go back to reference Ricci WM, Bellabarba C, Evanoff B, et al. Retrograde versus antegrade nailing of femoral shaft fractures. J Orthop Trauma. 2001;15:161–9.CrossRefPubMed Ricci WM, Bellabarba C, Evanoff B, et al. Retrograde versus antegrade nailing of femoral shaft fractures. J Orthop Trauma. 2001;15:161–9.CrossRefPubMed
14.
go back to reference Sanders DW, MacLeod M, Charyk-Stewart T, et al. Functional outcome and persistent disability after isolated fracture of the femur. Can J Surg. 2008;51:366–70.PubMedCentralPubMed Sanders DW, MacLeod M, Charyk-Stewart T, et al. Functional outcome and persistent disability after isolated fracture of the femur. Can J Surg. 2008;51:366–70.PubMedCentralPubMed
15.
go back to reference Butcher JL, MacKenzie EJ, Cushing B, et al. Long-term outcomes after lower extremity trauma. J Trauma. 1996;41:4–9.CrossRefPubMed Butcher JL, MacKenzie EJ, Cushing B, et al. Long-term outcomes after lower extremity trauma. J Trauma. 1996;41:4–9.CrossRefPubMed
16.
go back to reference el Moumni M, Voogd EH, ten Duis HJ, Wendt KW. Long-term functional outcome following intramedullary nailing of femoral shaft fractures. Injury. 2012;43:1154–8.CrossRefPubMed el Moumni M, Voogd EH, ten Duis HJ, Wendt KW. Long-term functional outcome following intramedullary nailing of femoral shaft fractures. Injury. 2012;43:1154–8.CrossRefPubMed
17.
go back to reference Paterno MV, Archdeacon MT. Is there a standard rehabilitation protocol after femoral intramedullary nailing? J Orthop Trauma. 2009;23:S39–46.CrossRefPubMed Paterno MV, Archdeacon MT. Is there a standard rehabilitation protocol after femoral intramedullary nailing? J Orthop Trauma. 2009;23:S39–46.CrossRefPubMed
18.
go back to reference Archdeacon M, Ford KR, Wyrick J, et al. A prospective functional outcome and motion analysis evaluation of the hip abductors after femur fracture and antegrade nailing. J Orthop Trauma. 2008;22:3–9.CrossRefPubMed Archdeacon M, Ford KR, Wyrick J, et al. A prospective functional outcome and motion analysis evaluation of the hip abductors after femur fracture and antegrade nailing. J Orthop Trauma. 2008;22:3–9.CrossRefPubMed
19.
go back to reference Ostrum RF, Agarwal A, Lakatos R, Poka A. Prospective comparison of retrograde and antegrade femoral intramedullary nailing. J Orthop Trauma. 2000;14:496–501.CrossRefPubMed Ostrum RF, Agarwal A, Lakatos R, Poka A. Prospective comparison of retrograde and antegrade femoral intramedullary nailing. J Orthop Trauma. 2000;14:496–501.CrossRefPubMed
20.
go back to reference Karaman O, Ayhan E, Kesmezacar H, et al. Rotational malalignment after closed intramedullary nailing of femoral shaft fractures and its influence on daily life. Eur J Orthop Surg Traumatol. 2014;24(7):1243–7.CrossRefPubMed Karaman O, Ayhan E, Kesmezacar H, et al. Rotational malalignment after closed intramedullary nailing of femoral shaft fractures and its influence on daily life. Eur J Orthop Surg Traumatol. 2014;24(7):1243–7.CrossRefPubMed
21.
go back to reference Skou ST, Graven-Nielsen T, Rasmussen S, et al. Widespread sensitization in patients with chronic pain after revision total knee arthroplasty. Pain. 2013;154:1588–94.CrossRefPubMed Skou ST, Graven-Nielsen T, Rasmussen S, et al. Widespread sensitization in patients with chronic pain after revision total knee arthroplasty. Pain. 2013;154:1588–94.CrossRefPubMed
22.
go back to reference Graven-Nielsen T, Wodehouse T, Langford RM, et al. Normalization of widespread hyperesthesia and facilitated spatial summation of deep-tissue pain in knee osteoarthritis patients after knee replacement. Arthritis Rheum. 2012;64:2907–16.CrossRefPubMed Graven-Nielsen T, Wodehouse T, Langford RM, et al. Normalization of widespread hyperesthesia and facilitated spatial summation of deep-tissue pain in knee osteoarthritis patients after knee replacement. Arthritis Rheum. 2012;64:2907–16.CrossRefPubMed
23.
go back to reference Marsh JL, Slongo TF, Agel J, et al. Fracture and Dislocation Classification Compendium—2007: orthopadic trauma assocoation classification, database and outcome committee. J Orthop Trauma. 2007;1–133. Marsh JL, Slongo TF, Agel J, et al. Fracture and Dislocation Classification Compendium—2007: orthopadic trauma assocoation classification, database and outcome committee. J Orthop Trauma. 2007;1–133.
26.
go back to reference Wittrup-Jensen KU, Lauridsen J, Gudex C, Pedersen KM. Generation of a danish TTO value set for EQ-5D health states. Scand J Public Health. 2009;37:459–66.CrossRefPubMed Wittrup-Jensen KU, Lauridsen J, Gudex C, Pedersen KM. Generation of a danish TTO value set for EQ-5D health states. Scand J Public Health. 2009;37:459–66.CrossRefPubMed
27.
go back to reference Rathleff CR, Baird WN, Olesen JL, et al. Hip and knee strength is not affected in 12–16-year-old adolescents with patellofemoral pain—a cross-sectional population-based study. PLoS One. 2013;8:e79153.PubMedCentralCrossRefPubMed Rathleff CR, Baird WN, Olesen JL, et al. Hip and knee strength is not affected in 12–16-year-old adolescents with patellofemoral pain—a cross-sectional population-based study. PLoS One. 2013;8:e79153.PubMedCentralCrossRefPubMed
28.
go back to reference Rikli RE, Jones CJ. Development and validity of a functional fitness test for community-residing older adults. J Aging Phys Act. 1999;7:127–59. Rikli RE, Jones CJ. Development and validity of a functional fitness test for community-residing older adults. J Aging Phys Act. 1999;7:127–59.
29.
go back to reference Parmar V, Shyam Kumar AJ, Harper WM. Reliability of the GAITRite walkway system for the quantification of temporo-spatial parameters of gait in young and older people. Gait Posture. 2006;23:523 (author reply 524–5). Parmar V, Shyam Kumar AJ, Harper WM. Reliability of the GAITRite walkway system for the quantification of temporo-spatial parameters of gait in young and older people. Gait Posture. 2006;23:523 (author reply 524–5).
30.
go back to reference Kuys SS, Brauer SG, Ada L. Test-retest reliability of the GAITRite system in people with stroke undergoing rehabilitation. Disabil Rehabil. 2011;33:1848–53.CrossRefPubMed Kuys SS, Brauer SG, Ada L. Test-retest reliability of the GAITRite system in people with stroke undergoing rehabilitation. Disabil Rehabil. 2011;33:1848–53.CrossRefPubMed
31.
go back to reference McDonough AL, Batavia M, Chen FC, et al. The validity and reliability of the GAITRite system’s measurements: a preliminary evaluation. Arch Phys Med Rehabil. 2001;82:419–25.CrossRefPubMed McDonough AL, Batavia M, Chen FC, et al. The validity and reliability of the GAITRite system’s measurements: a preliminary evaluation. Arch Phys Med Rehabil. 2001;82:419–25.CrossRefPubMed
32.
go back to reference Graven-Nielsen T, Arendt-Nielsen L. Assessment of mechanisms in localized and widespread musculoskeletal pain. Nat Rev Rheumatol. 2010;6:599–606.CrossRefPubMed Graven-Nielsen T, Arendt-Nielsen L. Assessment of mechanisms in localized and widespread musculoskeletal pain. Nat Rev Rheumatol. 2010;6:599–606.CrossRefPubMed
33.
go back to reference Helmy N, Jando VT, Lu T. Muscle function and functional outcome following standard antegrade reamed intramedullary nailing of isolated femoral shaft fractures. J Orthop Trauma. 2008;22:10–5.CrossRefPubMed Helmy N, Jando VT, Lu T. Muscle function and functional outcome following standard antegrade reamed intramedullary nailing of isolated femoral shaft fractures. J Orthop Trauma. 2008;22:10–5.CrossRefPubMed
34.
go back to reference Sorensen J, Davidsen M, Gudex C, et al. Danish EQ-5D population norms. Scand J Public Health. 2009;37:467–74.CrossRefPubMed Sorensen J, Davidsen M, Gudex C, et al. Danish EQ-5D population norms. Scand J Public Health. 2009;37:467–74.CrossRefPubMed
35.
go back to reference Ostrum RF, Agarwal A, Lakatos R, Poka A. Prospective comparison of retrograde and antegrade femoral intramedullary nailing. J Orthop Trauma. 2000;14:496–501.CrossRefPubMed Ostrum RF, Agarwal A, Lakatos R, Poka A. Prospective comparison of retrograde and antegrade femoral intramedullary nailing. J Orthop Trauma. 2000;14:496–501.CrossRefPubMed
36.
go back to reference Bain GI, Zacest AC, Paterson DC, et al. Abduction strength following intramedullary nailing of the femur. J Orthop Trauma. 1997;11:93–7.CrossRefPubMed Bain GI, Zacest AC, Paterson DC, et al. Abduction strength following intramedullary nailing of the femur. J Orthop Trauma. 1997;11:93–7.CrossRefPubMed
37.
go back to reference Ostrum RF, Agarwal A, Lakatos R, Poka A. Prospective comparison of retrograde and antegrade femoral intramedullary nailing. J Orthop Trauma. 2000;14:496–501.CrossRefPubMed Ostrum RF, Agarwal A, Lakatos R, Poka A. Prospective comparison of retrograde and antegrade femoral intramedullary nailing. J Orthop Trauma. 2000;14:496–501.CrossRefPubMed
38.
go back to reference Kapp W, Lindsey RW, Noble PC, et al. Long-term residual musculoskeletal deficits after femoral shaft fractures treated with intramedullary nailing. J Trauma. 2000;49:446–9.CrossRefPubMed Kapp W, Lindsey RW, Noble PC, et al. Long-term residual musculoskeletal deficits after femoral shaft fractures treated with intramedullary nailing. J Trauma. 2000;49:446–9.CrossRefPubMed
39.
go back to reference Hennrikus WL, Kasser JR, Rand F, et al. The function of the quadriceps muscle after a fracture of the femur in patients who are less than seventeen years old. J Bone Joint Surg Am. 1993;75:508–13.PubMed Hennrikus WL, Kasser JR, Rand F, et al. The function of the quadriceps muscle after a fracture of the femur in patients who are less than seventeen years old. J Bone Joint Surg Am. 1993;75:508–13.PubMed
40.
go back to reference Sanders DW, MacLeod M, Charyk-Stewart T, et al. Functional outcome and persistent disability after isolated fracture of the femur. Can J Surg. 2008;51:366–70.PubMedCentralPubMed Sanders DW, MacLeod M, Charyk-Stewart T, et al. Functional outcome and persistent disability after isolated fracture of the femur. Can J Surg. 2008;51:366–70.PubMedCentralPubMed
41.
go back to reference Riley JL, Robinson ME, Wise EA, et al. Sex differences in the perception of noxious experimental stimuli: a meta-analysis. Pain. 1998;74:181–7.CrossRefPubMed Riley JL, Robinson ME, Wise EA, et al. Sex differences in the perception of noxious experimental stimuli: a meta-analysis. Pain. 1998;74:181–7.CrossRefPubMed
42.
go back to reference Graven-Nielsen T, Arendt-Nielsen L. Gender differences in response to pain. Ugeskr Laeger. 2007;169:2425–7.PubMed Graven-Nielsen T, Arendt-Nielsen L. Gender differences in response to pain. Ugeskr Laeger. 2007;169:2425–7.PubMed
43.
go back to reference Tucker MC, Schwappach JR, Leighton RK, et al. Results of femoral intramedullary nailing in patients who are obese versus those who are not obese: a prospective multicenter comparison study. J Orthop Trauma. 2007;21:523–9.CrossRefPubMed Tucker MC, Schwappach JR, Leighton RK, et al. Results of femoral intramedullary nailing in patients who are obese versus those who are not obese: a prospective multicenter comparison study. J Orthop Trauma. 2007;21:523–9.CrossRefPubMed
Metadata
Title
Decreased muscle strength is associated with impaired long-term functional outcome after intramedullary nailing of femoral shaft fracture
Authors
P. Larsen
R. Elsoe
T. Graven-Nielsen
U. Laessoe
S. Rasmussen
Publication date
01-12-2015
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Trauma and Emergency Surgery / Issue 6/2015
Print ISSN: 1863-9933
Electronic ISSN: 1863-9941
DOI
https://doi.org/10.1007/s00068-014-0488-2

Other articles of this Issue 6/2015

European Journal of Trauma and Emergency Surgery 6/2015 Go to the issue

ESTES News 6.2015

ESTES News 6.2015