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08-09-2022 | Enterostomy | Original Article

Selective local postoperative radiotherapy for T3–T4 N0 laryngeal cancer

Authors: Dr. Meltem Dağdelen, Merve Şahin, Tuba Kurt Çatal, Halil Cumhur Yıldırım, Songül Çavdar Karaçam, Kimia Çepni, Ömer Erol Uzel

Published in: Strahlentherapie und Onkologie | Issue 11/2022

Abstract

Purpose

We aimed to investigate the appropriate postoperative radiotherapy dose and selective volume in T3–4 N0 laryngeal cancer patients treated with either total or partial laryngectomy.

Methods

Patients who received radiotherapy for locally advanced (T3–T4) and pathologic node-negative (N0) squamous cell laryngeal cancer were retrospectively evaluated. Radiotherapy was applied to median 60 Gy (range 54–60 Gy) as selective local radiotherapy (±stoma). The local treatment areas included postoperative bed + laryngeal area for patients with a partial laryngectomy, and the postoperative bed only for patients with total laryngectomy.

Results

The median follow-up time was 59 months and 52 patients were included. The 2‑year, 5‑year, and 8‑year locoregional recurrence controls (LRC) were 95.6%. The 2‑year and 5‑year OS rates were 93.8% and 78.9%, respectively. The 5‑year OS for age < 60 years was 95.8%, for above 60 years 56.5%.

Conclusion

Our data suggest that local selective irradiation to the postoperative bed + stoma is enough in patients with T3–4 N0 laryngeal cancer without applying elective nodal irradiation.

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Title: Selective local postoperative radiotherapy for T3–T4 N0 laryngeal cancer
Authors: Dr. Meltem Dağdelen
Merve Şahin
Tuba Kurt Çatal
Halil Cumhur Yıldırım
Songül Çavdar Karaçam
Kimia Çepni
Ömer Erol Uzel
Publication date: 08-09-2022
Publisher: Springer Berlin Heidelberg
Keywords: Enterostomy
Laryngectomy
Enterostomy
Radiotherapy
Laryngeal Cancer
Laryngeal Cancer
Published in: Strahlentherapie und Onkologie / Issue 11/2022
Print ISSN: 0179-7158
Electronic ISSN: 1439-099X
DOI: https://doi.org/10.1007/s00066-022-01999-y

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Selective local postoperative radiotherapy for T3–T4 N0 laryngeal cancer

Abstract

Purpose

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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