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Published in: Strahlentherapie und Onkologie 9/2018

01-09-2018 | Review Article

Neoadjuvant chemotherapy for breast cancer—background for the indication of locoregional treatment

Authors: David Krug, René Baumann, Wilfried Budach, Jürgen Dunst, Petra Feyer, Rainer Fietkau, Wulf Haase, Wolfgang Harms, Thomas Hehr, Marc D. Piroth, Felix Sedlmayer, Rainer Souchon, Frederik Wenz, Rolf Sauer, Breast Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO)

Published in: Strahlentherapie und Onkologie | Issue 9/2018

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Abstract

Neoadjuvant chemotherapy (NACT) has been widely adopted into the multidisciplinary management of breast cancer. The prognostic impact of treatment response has been clearly demonstrated. However, the impact of treatment response on the indication for adjuvant radiotherapy is unclear. This review summarizes important implications of NACT and treatment response on the risk of recurrence and locoregional multidisciplinary management from the standpoint of radiation oncology.
Literature
21.
go back to reference Schneeweiss A, Möbus V, Tesch H et al (2017) A randomised phase III trial comparing two dose-dense, dose-intensified approaches (ETC and PM(Cb)) for neoadjuvant treatment of patients with high-risk early breast cancer (GeparOcto). J Clin Oncol 35:abstr 518CrossRef Schneeweiss A, Möbus V, Tesch H et al (2017) A randomised phase III trial comparing two dose-dense, dose-intensified approaches (ETC and PM(Cb)) for neoadjuvant treatment of patients with high-risk early breast cancer (GeparOcto). J Clin Oncol 35:abstr 518CrossRef
37.
Metadata
Title
Neoadjuvant chemotherapy for breast cancer—background for the indication of locoregional treatment
Authors
David Krug
René Baumann
Wilfried Budach
Jürgen Dunst
Petra Feyer
Rainer Fietkau
Wulf Haase
Wolfgang Harms
Thomas Hehr
Marc D. Piroth
Felix Sedlmayer
Rainer Souchon
Frederik Wenz
Rolf Sauer
Breast Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO)
Publication date
01-09-2018
Publisher
Springer Berlin Heidelberg
Published in
Strahlentherapie und Onkologie / Issue 9/2018
Print ISSN: 0179-7158
Electronic ISSN: 1439-099X
DOI
https://doi.org/10.1007/s00066-018-1329-8

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